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Analysis of Depression and Anxiety in Patients With Tinnitus: A Focus on Specific Age Groups and Sex‐Related Differences.

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Title: Analysis of Depression and Anxiety in Patients With Tinnitus: A Focus on Specific Age Groups and Sex‐Related Differences.
Authors: Zhou, Jing (AUTHOR), Liu, Yuehong (AUTHOR), Xie, Hongbo (AUTHOR), Yang, Siyi (AUTHOR), Jiang, Yun (AUTHOR), Han, Zhao (AUTHOR), Manthey, Marie Kristin (AUTHOR)
Source: Depression & Anxiety (1091-4269). 5/12/2026, Vol. 2026, p1-8. 8p.
Subjects: Tinnitus, Anxiety, Psychological tests, Gender differences (Psychology), Quality of life, Age groups, Mental depression, Insomnia
Abstract: Objective: To investigate the relationships between anxiety, depression, and insomnia and tinnitus severity among high‐functioning employed adults, stratified by age and gender, and to describe age‐ and gender‐specific patterns of prevalence and symptom burden in order to support a biopsychosocial framework for understanding tinnitus onset, progression, and clinical management. Methods: An analysis was performed on data from 745 patients with chronic subjective tinnitus, aged 25–60 years, to assess levels of anxiety (HADS‐A), depression (HADS‐D), insomnia (ISI), and the perceived severity of tinnitus (THI and VAS). Results: The findings showed that anxiety was significantly correlated with the tinnitus Handicap Inventory in younger patients, particularly in men (r = 0.611, p < 0.001) and women (r = 0.577, p < 0.001) aged 25–40 years. In women aged 51–60 years, depression demonstrated the strongest association with tinnitus (r = 0.545, p < 0.001). In the overall cohort, insomnia exhibited a weak but statistically significant correlation with tinnitus (r ≤ 0.3). Additionally, women were more likely to link tinnitus loudness to reduced quality of life, especially in the 25–40 (r = 0.722, p < 0.01) and 51–60 (r = 0.689, p < 0.01) age groups. Conclusion: The findings indicate that anxiety in younger patients is closely related to tinnitus, whereas depressive symptoms are more prominent among middle‐aged and older women. These variations indicate that patients with tinnitus may present different psychological profiles across gender and age groups. Future research may further explore the underlying pathophysiological mechanisms of tinnitus and examine its progression through long‐term follow‐up to improve understanding of its clinical heterogeneity. [ABSTRACT FROM AUTHOR]
Copyright of Depression & Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Analysis of Depression and Anxiety in Patients With Tinnitus: A Focus on Specific Age Groups and Sex‐Related Differences.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Zhou%2C+Jing%22&quot;&gt;Zhou, Jing&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Liu%2C+Yuehong%22&quot;&gt;Liu, Yuehong&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Xie%2C+Hongbo%22&quot;&gt;Xie, Hongbo&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Yang%2C+Siyi%22&quot;&gt;Yang, Siyi&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Jiang%2C+Yun%22&quot;&gt;Jiang, Yun&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Han%2C+Zhao%22&quot;&gt;Han, Zhao&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Manthey%2C+Marie+Kristin%22&quot;&gt;Manthey, Marie Kristin&lt;/searchLink&gt; (AUTHOR)
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– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective: To investigate the relationships between anxiety, depression, and insomnia and tinnitus severity among high‐functioning employed adults, stratified by age and gender, and to describe age‐ and gender‐specific patterns of prevalence and symptom burden in order to support a biopsychosocial framework for understanding tinnitus onset, progression, and clinical management. Methods: An analysis was performed on data from 745 patients with chronic subjective tinnitus, aged 25–60 years, to assess levels of anxiety (HADS‐A), depression (HADS‐D), insomnia (ISI), and the perceived severity of tinnitus (THI and VAS). Results: The findings showed that anxiety was significantly correlated with the tinnitus Handicap Inventory in younger patients, particularly in men (r = 0.611, p &lt; 0.001) and women (r = 0.577, p &lt; 0.001) aged 25–40 years. In women aged 51–60 years, depression demonstrated the strongest association with tinnitus (r = 0.545, p &lt; 0.001). In the overall cohort, insomnia exhibited a weak but statistically significant correlation with tinnitus (r ≤ 0.3). Additionally, women were more likely to link tinnitus loudness to reduced quality of life, especially in the 25–40 (r = 0.722, p &lt; 0.01) and 51–60 (r = 0.689, p &lt; 0.01) age groups. Conclusion: The findings indicate that anxiety in younger patients is closely related to tinnitus, whereas depressive symptoms are more prominent among middle‐aged and older women. These variations indicate that patients with tinnitus may present different psychological profiles across gender and age groups. Future research may further explore the underlying pathophysiological mechanisms of tinnitus and examine its progression through long‐term follow‐up to improve understanding of its clinical heterogeneity. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Depression &amp; Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1155/da/9170627
    Languages:
      – Code: eng
        Text: English
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        PageCount: 8
        StartPage: 1
    Subjects:
      – SubjectFull: Tinnitus
        Type: general
      – SubjectFull: Anxiety
        Type: general
      – SubjectFull: Psychological tests
        Type: general
      – SubjectFull: Gender differences (Psychology)
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      – SubjectFull: Quality of life
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      – SubjectFull: Age groups
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      – SubjectFull: Mental depression
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      – SubjectFull: Insomnia
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            NameFull: Zhou, Jing
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              Text: 5/12/2026
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              Value: 2026
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