View in EDS HTML Full Text PDF Full Text

The impact of initial depression and anxiety levels on symptom severity change during psychological treatment for common mental disorders: a systematic review.

Saved in:
Bibliographic Details
Title: The impact of initial depression and anxiety levels on symptom severity change during psychological treatment for common mental disorders: a systematic review.
Authors: Kamardina, Anna (AUTHOR), Saunders, Rob (AUTHOR), Broglia, Emma (AUTHOR)
Source: Journal of Mental Health. Jun2026, Vol. 35 Issue 3, p354-374. 21p.
Subjects: Anxiety treatment, Mental illness treatment, Psychotherapy, Pearson correlation (Statistics), Suicidal ideation, Unemployment, Severity of illness index, Meta-analysis, Descriptive statistics, Systematic reviews, MEDLINE, Medical databases, Online information services, Data analysis software, Confidence intervals, Interpersonal relations, Mental depression, Psychology information storage & retrieval systems, Regression analysis, Adults
Geographic Terms: United Kingdom
Abstract: Background: Depression and anxiety are highly comorbid conditions, which may impact treatment response. Aims: We intended to examine how depression and anxiety symptoms change during psychological interventions for adults and how the initial severity is associated with distinct trajectory classes. Methods: We identified papers examining longitudinal changes in depression and anxiety. Trajectory classes were grouped into responders, improvers and non-improvers. Narrative synthesis, alongside meta-analysis, was applied to explore the number and nature of classes, their associations with study characteristics and predictors of trajectory class membership. This study was pre-registered on International Prospective Register of Systematic Reviews (PROSPERO) (CRD42023393155), and the authors followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance. Results: We identified 18 papers, including 22 models with two to six classes. Responding and non-improving classes prevailed. Meta-regression revealed no characteristics associated with the proportion of these classes. Initial depression and anxiety levels predicted trajectory class membership for each other, but not always non-response. Unemployment, suicidality, social functioning impairment, treatment type and medication use predicted following non-responding trajectory. Conclusion: Our findings highlight the complex relationship between initial anxiety and depression severity and their changes during psychological interventions. They provide practitioners with insights into factors associated with non-response patterns of symptom change. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Mental Health is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 194088908
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The impact of initial depression and anxiety levels on symptom severity change during psychological treatment for common mental disorders: a systematic review.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Kamardina%2C+Anna%22">Kamardina, Anna</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Saunders%2C+Rob%22">Saunders, Rob</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Broglia%2C+Emma%22">Broglia, Emma</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Journal+of+Mental+Health%22">Journal of Mental Health</searchLink>. Jun2026, Vol. 35 Issue 3, p354-374. 21p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Anxiety+treatment%22">Anxiety treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+illness+treatment%22">Mental illness treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Psychotherapy%22">Psychotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Pearson+correlation+%28Statistics%29%22">Pearson correlation (Statistics)</searchLink><br /><searchLink fieldCode="DE" term="%22Suicidal+ideation%22">Suicidal ideation</searchLink><br /><searchLink fieldCode="DE" term="%22Unemployment%22">Unemployment</searchLink><br /><searchLink fieldCode="DE" term="%22Severity+of+illness+index%22">Severity of illness index</searchLink><br /><searchLink fieldCode="DE" term="%22Meta-analysis%22">Meta-analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Systematic+reviews%22">Systematic reviews</searchLink><br /><searchLink fieldCode="DE" term="%22MEDLINE%22">MEDLINE</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+databases%22">Medical databases</searchLink><br /><searchLink fieldCode="DE" term="%22Online+information+services%22">Online information services</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis+software%22">Data analysis software</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Interpersonal+relations%22">Interpersonal relations</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Psychology+information+storage+%26+retrieval+systems%22">Psychology information storage & retrieval systems</searchLink><br /><searchLink fieldCode="DE" term="%22Regression+analysis%22">Regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Adults%22">Adults</searchLink>
– Name: SubjectGeographic
  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22United+Kingdom%22">United Kingdom</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Depression and anxiety are highly comorbid conditions, which may impact treatment response. Aims: We intended to examine how depression and anxiety symptoms change during psychological interventions for adults and how the initial severity is associated with distinct trajectory classes. Methods: We identified papers examining longitudinal changes in depression and anxiety. Trajectory classes were grouped into responders, improvers and non-improvers. Narrative synthesis, alongside meta-analysis, was applied to explore the number and nature of classes, their associations with study characteristics and predictors of trajectory class membership. This study was pre-registered on International Prospective Register of Systematic Reviews (PROSPERO) (CRD42023393155), and the authors followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance. Results: We identified 18 papers, including 22 models with two to six classes. Responding and non-improving classes prevailed. Meta-regression revealed no characteristics associated with the proportion of these classes. Initial depression and anxiety levels predicted trajectory class membership for each other, but not always non-response. Unemployment, suicidality, social functioning impairment, treatment type and medication use predicted following non-responding trajectory. Conclusion: Our findings highlight the complex relationship between initial anxiety and depression severity and their changes during psychological interventions. They provide practitioners with insights into factors associated with non-response patterns of symptom change. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Mental Health is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=194088908
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/09638237.2026.2622085
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 21
        StartPage: 354
    Subjects:
      – SubjectFull: Anxiety treatment
        Type: general
      – SubjectFull: Mental illness treatment
        Type: general
      – SubjectFull: Psychotherapy
        Type: general
      – SubjectFull: Pearson correlation (Statistics)
        Type: general
      – SubjectFull: Suicidal ideation
        Type: general
      – SubjectFull: Unemployment
        Type: general
      – SubjectFull: Severity of illness index
        Type: general
      – SubjectFull: Meta-analysis
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Systematic reviews
        Type: general
      – SubjectFull: MEDLINE
        Type: general
      – SubjectFull: Medical databases
        Type: general
      – SubjectFull: Online information services
        Type: general
      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Interpersonal relations
        Type: general
      – SubjectFull: Mental depression
        Type: general
      – SubjectFull: Psychology information storage & retrieval systems
        Type: general
      – SubjectFull: Regression analysis
        Type: general
      – SubjectFull: Adults
        Type: general
      – SubjectFull: United Kingdom
        Type: general
    Titles:
      – TitleFull: The impact of initial depression and anxiety levels on symptom severity change during psychological treatment for common mental disorders: a systematic review.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Kamardina, Anna
      – PersonEntity:
          Name:
            NameFull: Saunders, Rob
      – PersonEntity:
          Name:
            NameFull: Broglia, Emma
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: Jun2026
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 09638237
          Numbering:
            – Type: volume
              Value: 35
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Journal of Mental Health
              Type: main
ResultId 1