Symptom burden in cancer survivorship: insights from a survivorship program’s patient-reported outcomes database.
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| Title: | Symptom burden in cancer survivorship: insights from a survivorship program’s patient-reported outcomes database. |
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| Authors: | Tlusty, Gisele C. (AUTHOR), Choi, Eunju (AUTHOR), Alsbrook, Karen (AUTHOR), Gilmore, Katherine R. (AUTHOR), Rollins, Johnny (AUTHOR), Dains, Joyce (AUTHOR), Fadol, Anecita (AUTHOR), Roth, Michael E. (AUTHOR), Hacker, Eileen D. (AUTHOR) |
| Source: | Quality of Life Research. Aug2026, Vol. 35 Issue 8, p1-12. 12p. |
| Abstract: | Purpose: This study aimed to examine the symptom burden reported by survivors treated in survivorship clinics by describing the severity of symptoms and symptom interference with life activities, comparing symptom severity by sex, and identifying predictors of the three most prevalent moderate to severe symptoms. Methods: This secondary data analysis examined patient-reported symptom burden data using the MD Anderson Symptom Inventory collected for clinical purposes from January to December 2023. Sex differences in symptom burden were compared using t-tests. Multivariate logistic regressions identified predictors of the three most prevalent moderate to severe symptoms. Results: Among 2550 survivors (mean age 61.9 ± 12.1 years; 69.9% female, 36.4% breast cancer), the average time in survivorship care was 4.04 ± 4.00 years. Over 75% of survivors reported experiencing ≥ 1 symptom, and 45% reported ≥ 1 moderate-severe symptom. The three most prevalent moderate to severe symptoms were fatigue (25%), sleep disturbance (24%), and problems remembering (15%). Compared with males, females reported significantly more symptoms (p < 0.05) and more moderate to severe symptoms (p < 0.01). Female survivors and those under the age of 65 were more likely to report moderate to severe fatigue, sleep disturbance, and problems remembering (all p < 0.01). Conclusion: The high prevalence of persistent symptoms among cancer survivors in this sample supports the need for routine symptom assessments in survivorship care. Age and sex are important considerations in tailoring supportive interventions. As the population of cancer survivors grows, understanding symptom burden across diagnoses is critical to inform effective supportive care strategies. [ABSTRACT FROM AUTHOR] |
| Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 194738290 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Symptom burden in cancer survivorship: insights from a survivorship program’s patient-reported outcomes database. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Tlusty%2C+Gisele+C%2E%22">Tlusty, Gisele C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Choi%2C+Eunju%22">Choi, Eunju</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Alsbrook%2C+Karen%22">Alsbrook, Karen</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gilmore%2C+Katherine+R%2E%22">Gilmore, Katherine R.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rollins%2C+Johnny%22">Rollins, Johnny</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Dains%2C+Joyce%22">Dains, Joyce</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fadol%2C+Anecita%22">Fadol, Anecita</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Roth%2C+Michael+E%2E%22">Roth, Michael E.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hacker%2C+Eileen+D%2E%22">Hacker, Eileen D.</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Quality+of+Life+Research%22">Quality of Life Research</searchLink>. Aug2026, Vol. 35 Issue 8, p1-12. 12p. – Name: Abstract Label: Abstract Group: Ab Data: Purpose: This study aimed to examine the symptom burden reported by survivors treated in survivorship clinics by describing the severity of symptoms and symptom interference with life activities, comparing symptom severity by sex, and identifying predictors of the three most prevalent moderate to severe symptoms. Methods: This secondary data analysis examined patient-reported symptom burden data using the MD Anderson Symptom Inventory collected for clinical purposes from January to December 2023. Sex differences in symptom burden were compared using t-tests. Multivariate logistic regressions identified predictors of the three most prevalent moderate to severe symptoms. Results: Among 2550 survivors (mean age 61.9 ± 12.1 years; 69.9% female, 36.4% breast cancer), the average time in survivorship care was 4.04 ± 4.00 years. Over 75% of survivors reported experiencing ≥ 1 symptom, and 45% reported ≥ 1 moderate-severe symptom. The three most prevalent moderate to severe symptoms were fatigue (25%), sleep disturbance (24%), and problems remembering (15%). Compared with males, females reported significantly more symptoms (p < 0.05) and more moderate to severe symptoms (p < 0.01). Female survivors and those under the age of 65 were more likely to report moderate to severe fatigue, sleep disturbance, and problems remembering (all p < 0.01). Conclusion: The high prevalence of persistent symptoms among cancer survivors in this sample supports the need for routine symptom assessments in survivorship care. Age and sex are important considerations in tailoring supportive interventions. As the population of cancer survivors grows, understanding symptom burden across diagnoses is critical to inform effective supportive care strategies. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s11136-026-04321-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 12 StartPage: 1 Titles: – TitleFull: Symptom burden in cancer survivorship: insights from a survivorship program’s patient-reported outcomes database. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tlusty, Gisele C. – PersonEntity: Name: NameFull: Choi, Eunju – PersonEntity: Name: NameFull: Alsbrook, Karen – PersonEntity: Name: NameFull: Gilmore, Katherine R. – PersonEntity: Name: NameFull: Rollins, Johnny – PersonEntity: Name: NameFull: Dains, Joyce – PersonEntity: Name: NameFull: Fadol, Anecita – PersonEntity: Name: NameFull: Roth, Michael E. – PersonEntity: Name: NameFull: Hacker, Eileen D. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: Aug2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 09629343 Numbering: – Type: volume Value: 35 – Type: issue Value: 8 Titles: – TitleFull: Quality of Life Research Type: main |
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