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How Does Fertility Stress Influence Depressive Symptoms in Female Partners of Infertile Couples in China? A Parallel Mediation Analysis of Infertility Stigma and Family Function.

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Title: How Does Fertility Stress Influence Depressive Symptoms in Female Partners of Infertile Couples in China? A Parallel Mediation Analysis of Infertility Stigma and Family Function.
Authors: Li, Yingqi (AUTHOR), Wang, Ying (AUTHOR), Wang, Meihong (AUTHOR), Yang, Hua (AUTHOR), Qiu, Lei (AUTHOR), Manthey, Marie Kristin (AUTHOR)
Source: Depression & Anxiety (1091-4269). 6/27/2026, Vol. 2026, p1-12. 12p.
Subjects: Infertility, Psychological stress, East Asians, Social stigma, Mental depression, Spouses, Mediation (Statistics), Family health
Geographic Terms: China
Abstract: Objective: This study aims to explore the impact of fertility stress on depressive symptoms, with a focus on analyzing the potential mediating effects of infertility stigma and family function in this process. Methods: A cross‐sectional design was employed in which 1294 female partners of infertile couples were recruited from two tertiary‐grade A hospitals in Hainan Province, China. Fertility stress, depressive symptoms, infertility stigma, and family function were assessed with validated self‐report questionnaires. Structural equation modeling (SEM) was used to estimate the direct effect of fertility stress and the parallel mediating effects of infertility stigma and family function. Results: The prevalence rate of depressive symptoms was 26.35%. The direct effect model indicated a significant positive association between fertility stress and depressive symptoms (β = 0.260, p < 0.001). The parallel mediation model revealed that infertility stigma (β = 0.176, p < 0.001) and family function (β = 0.052, p < 0.001) exerted full mediating effects. Specifically, fertility stress indirectly increased depressive symptoms by exacerbating infertility stigma; concurrently, low levels of family function exacerbated the negative impact of fertility stress on mental health. Conclusion: Fertility stress not only directly affects depressive symptoms, but also indirectly exacerbates depressive symptoms by intensifying infertility stigma and impairing family function. This study provides a new perspective for understanding the mental health mechanism in female partners of infertile couples, emphasizing that psychological interventions need to simultaneously focus on reducing infertility stigma and improving family function, which may offer a basis for informing relevant clinical practices and public health policies. [ABSTRACT FROM AUTHOR]
Copyright of Depression & Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: How Does Fertility Stress Influence Depressive Symptoms in Female Partners of Infertile Couples in China? A Parallel Mediation Analysis of Infertility Stigma and Family Function.
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– Name: Abstract
  Label: Abstract
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  Data: Objective: This study aims to explore the impact of fertility stress on depressive symptoms, with a focus on analyzing the potential mediating effects of infertility stigma and family function in this process. Methods: A cross‐sectional design was employed in which 1294 female partners of infertile couples were recruited from two tertiary‐grade A hospitals in Hainan Province, China. Fertility stress, depressive symptoms, infertility stigma, and family function were assessed with validated self‐report questionnaires. Structural equation modeling (SEM) was used to estimate the direct effect of fertility stress and the parallel mediating effects of infertility stigma and family function. Results: The prevalence rate of depressive symptoms was 26.35%. The direct effect model indicated a significant positive association between fertility stress and depressive symptoms (β = 0.260, p &lt; 0.001). The parallel mediation model revealed that infertility stigma (β = 0.176, p &lt; 0.001) and family function (β = 0.052, p &lt; 0.001) exerted full mediating effects. Specifically, fertility stress indirectly increased depressive symptoms by exacerbating infertility stigma; concurrently, low levels of family function exacerbated the negative impact of fertility stress on mental health. Conclusion: Fertility stress not only directly affects depressive symptoms, but also indirectly exacerbates depressive symptoms by intensifying infertility stigma and impairing family function. This study provides a new perspective for understanding the mental health mechanism in female partners of infertile couples, emphasizing that psychological interventions need to simultaneously focus on reducing infertility stigma and improving family function, which may offer a basis for informing relevant clinical practices and public health policies. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Depression &amp; Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1155/da/5703300
    Languages:
      – Code: eng
        Text: English
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      Pagination:
        PageCount: 12
        StartPage: 1
    Subjects:
      – SubjectFull: Infertility
        Type: general
      – SubjectFull: Psychological stress
        Type: general
      – SubjectFull: East Asians
        Type: general
      – SubjectFull: Social stigma
        Type: general
      – SubjectFull: Mental depression
        Type: general
      – SubjectFull: Spouses
        Type: general
      – SubjectFull: Mediation (Statistics)
        Type: general
      – SubjectFull: Family health
        Type: general
      – SubjectFull: China
        Type: general
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      – TitleFull: How Does Fertility Stress Influence Depressive Symptoms in Female Partners of Infertile Couples in China? A Parallel Mediation Analysis of Infertility Stigma and Family Function.
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              Text: 6/27/2026
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