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Concurrent Polysubstance Use Profiles in Young Nightlife Attendees in Argentina: Harm Reduction Strategies and Their Impact on Negative Consequences.

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Title: Concurrent Polysubstance Use Profiles in Young Nightlife Attendees in Argentina: Harm Reduction Strategies and Their Impact on Negative Consequences.
Authors: Musso, Emilia (AUTHOR), Vera, Belén V. (AUTHOR), Caneto, Florencia (AUTHOR), Godoy, Juan C. (AUTHOR), Fernández Calderón, Fermín (AUTHOR)
Source: Substance Use & Misuse. 2026, Vol. 61 Issue 10, p1581-1592. 12p.
Subjects: Substance abuse, Cross-sectional method, Cocaine, Recreation, Methamphetamine, Research funding, Ecstasy (Drug), Multiple regression analysis, Structural equation modeling, Amphetamines, Descriptive statistics, Chi-squared test, Harm reduction, Surveys, Social skills, Research methodology, Drug abuse, One-way analysis of variance, Alcoholism, Cannabis (Genus), Data analysis software, Psychiatric drugs, Disease complications
Geographic Terms: Argentina
Abstract: Background: Polysubstance use is common in nightlife settings and has been linked to a variety of negative outcomes. Harm reduction strategies (HRS), which aim to reduce harms, may differ across consumption patterns. This paper identifies polysubstance use classes among young attendees of recreational settings, examines their HRS use, and explores associations with negative outcomes by use pattern. Methods: 596 Argentinean polysubstance users aged 18–35 who attended recreational settings completed a survey assessing substance use, HRS use, and consequences experienced. Latent Class Analysis identified polysubstance use patterns. Hierarchical multiple regression was used to assess associations between HRS use and the experimentation of negative consequences within classes. Results: Three classes of concurrent polysubstance use were identified: Low, Moderate, and Severe. Participants in the Moderate and Severe Polysubstance Use classes employed a greater number of HRS but also experienced psychological and social negative consequences more frequently. Within the different polysubstance use classes, significant association between the use of certain harm reduction strategies and a lower likelihood of reporting substance-related harms was found. Conclusions: Our study enhances understanding of the relationship between HRS and substance-related consequences across polysubstance use profiles. This should inform harm reduction messages for young people who use multiple drugs. [ABSTRACT FROM AUTHOR]
Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Concurrent Polysubstance Use Profiles in Young Nightlife Attendees in Argentina: Harm Reduction Strategies and Their Impact on Negative Consequences.
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  Data: <searchLink fieldCode="AR" term="%22Musso%2C+Emilia%22">Musso, Emilia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Vera%2C+Belén+V%2E%22">Vera, Belén V.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Caneto%2C+Florencia%22">Caneto, Florencia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Godoy%2C+Juan+C%2E%22">Godoy, Juan C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fernández+Calderón%2C+Fermín%22">Fernández Calderón, Fermín</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Substance+Use+%26+Misuse%22">Substance Use & Misuse</searchLink>. 2026, Vol. 61 Issue 10, p1581-1592. 12p.
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  Data: <searchLink fieldCode="DE" term="%22Substance+abuse%22">Substance abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Cross-sectional+method%22">Cross-sectional method</searchLink><br /><searchLink fieldCode="DE" term="%22Cocaine%22">Cocaine</searchLink><br /><searchLink fieldCode="DE" term="%22Recreation%22">Recreation</searchLink><br /><searchLink fieldCode="DE" term="%22Methamphetamine%22">Methamphetamine</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Ecstasy+%28Drug%29%22">Ecstasy (Drug)</searchLink><br /><searchLink fieldCode="DE" term="%22Multiple+regression+analysis%22">Multiple regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Structural+equation+modeling%22">Structural equation modeling</searchLink><br /><searchLink fieldCode="DE" term="%22Amphetamines%22">Amphetamines</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Chi-squared+test%22">Chi-squared test</searchLink><br /><searchLink fieldCode="DE" term="%22Harm+reduction%22">Harm reduction</searchLink><br /><searchLink fieldCode="DE" term="%22Surveys%22">Surveys</searchLink><br /><searchLink fieldCode="DE" term="%22Social+skills%22">Social skills</searchLink><br /><searchLink fieldCode="DE" term="%22Research+methodology%22">Research methodology</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+abuse%22">Drug abuse</searchLink><br /><searchLink fieldCode="DE" term="%22One-way+analysis+of+variance%22">One-way analysis of variance</searchLink><br /><searchLink fieldCode="DE" term="%22Alcoholism%22">Alcoholism</searchLink><br /><searchLink fieldCode="DE" term="%22Cannabis+%28Genus%29%22">Cannabis (Genus)</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis+software%22">Data analysis software</searchLink><br /><searchLink fieldCode="DE" term="%22Psychiatric+drugs%22">Psychiatric drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+complications%22">Disease complications</searchLink>
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  Label: Geographic Terms
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  Data: <searchLink fieldCode="DE" term="%22Argentina%22">Argentina</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Polysubstance use is common in nightlife settings and has been linked to a variety of negative outcomes. Harm reduction strategies (HRS), which aim to reduce harms, may differ across consumption patterns. This paper identifies polysubstance use classes among young attendees of recreational settings, examines their HRS use, and explores associations with negative outcomes by use pattern. Methods: 596 Argentinean polysubstance users aged 18–35 who attended recreational settings completed a survey assessing substance use, HRS use, and consequences experienced. Latent Class Analysis identified polysubstance use patterns. Hierarchical multiple regression was used to assess associations between HRS use and the experimentation of negative consequences within classes. Results: Three classes of concurrent polysubstance use were identified: Low, Moderate, and Severe. Participants in the Moderate and Severe Polysubstance Use classes employed a greater number of HRS but also experienced psychological and social negative consequences more frequently. Within the different polysubstance use classes, significant association between the use of certain harm reduction strategies and a lower likelihood of reporting substance-related harms was found. Conclusions: Our study enhances understanding of the relationship between HRS and substance-related consequences across polysubstance use profiles. This should inform harm reduction messages for young people who use multiple drugs. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=194999430
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/10826084.2026.2613715
    Languages:
      – Code: eng
        Text: English
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      Pagination:
        PageCount: 12
        StartPage: 1581
    Subjects:
      – SubjectFull: Substance abuse
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Cocaine
        Type: general
      – SubjectFull: Recreation
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      – SubjectFull: Methamphetamine
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      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Ecstasy (Drug)
        Type: general
      – SubjectFull: Multiple regression analysis
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      – SubjectFull: Structural equation modeling
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      – SubjectFull: Amphetamines
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      – SubjectFull: Descriptive statistics
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      – SubjectFull: Chi-squared test
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      – SubjectFull: Harm reduction
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      – SubjectFull: Argentina
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      – TitleFull: Concurrent Polysubstance Use Profiles in Young Nightlife Attendees in Argentina: Harm Reduction Strategies and Their Impact on Negative Consequences.
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              Text: 2026
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