The Roles of Family Functioning, Attachment Status, Emotion Regulation Skills and Traumatic Experiences in Adolescents with Substance Use Disorder and Their Potential Effects on Polysubstance Use.

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Title: The Roles of Family Functioning, Attachment Status, Emotion Regulation Skills and Traumatic Experiences in Adolescents with Substance Use Disorder and Their Potential Effects on Polysubstance Use.
Authors: İmrek, Yasemin (AUTHOR), Tufan, Ali Evren (AUTHOR)
Source: Substance Use & Misuse. 2026, Vol. 61 Issue 10, p1777-1788. 12p.
Subjects: Substance abuse risk factors, Cross-sectional method, Self-evaluation, Parents, Blood testing, Data analysis, T-test (Statistics), Child abuse, Alexithymia, Affinity groups, Attachment behavior, Statistical sampling, Fisher exact test, Probability theory, Logistic regression analysis, Questionnaires, Family relations, Multivariate analysis, Chi-squared test, Mann Whitney U Test, Urinalysis, Statistics, Factor analysis, Data analysis software, Disease complications, Adolescence
Abstract: Background: Polysubstance use during adolescence represents a severe form of substance use disorder (SUD) and is associated with poorer clinical outcomes. Although family functioning, attachment insecurity, emotion regulation difficulties, and childhood trauma have each been linked to adolescent substance use, their relative contributions to polysubstance use remain unclear. Objectives: This study aimed to examine the associations between family functioning, attachment, emotion regulation (ER) difficulties, and childhood trauma in adolescents with SUD, with a focus on their roles in polysubstance use. We hypothesized that ER difficulties would independently predict polysubstance use after controlling for other variables and explored mediation (via attachment) and moderation (via peer attachment) effects. Methods: This cross-sectional study included 54 adolescents receiving inpatient treatment for SUD. Validated self-report measures assessed family functioning, attachment to parents and peers, emotion regulation difficulties, and childhood traumatic experiences. Polysubstance use was defined as the intentional use of two or more substances meeting diagnostic criteria within the past year. Associations were examined using partial correlations with false discovery rate correction and hierarchical logistic regression. Exploratory mediation and moderation analyses were conducted. Results: Emotion regulation difficulties survived as the only variable reaching threshold in exploratory analyses, although estimates were imprecise and should be interpreted cautiously. While healthier family functioning initially appeared protective, this association was attenuated when childhood trauma was included in the models. Family dysfunction was associated with insecure parental attachment and higher levels of emotional and physical abuse and neglect. Attachment variables neither independently predicted polysubstance use nor mediated or moderated the observed associations. Conclusions: Emotion regulation difficulties may be associated with polysubstance use in adolescents with SUD. Trauma exposure may undermine family-level protective effects, possibly pointing to the need for trauma-informed, emotion regulation–focused interventions in adolescent addiction treatment. [ABSTRACT FROM AUTHOR]
Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: The Roles of Family Functioning, Attachment Status, Emotion Regulation Skills and Traumatic Experiences in Adolescents with Substance Use Disorder and Their Potential Effects on Polysubstance Use.
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  Data: <searchLink fieldCode="AR" term="%22İmrek%2C+Yasemin%22">İmrek, Yasemin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tufan%2C+Ali+Evren%22">Tufan, Ali Evren</searchLink> (AUTHOR)
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– Name: Abstract
  Label: Abstract
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  Data: Background: Polysubstance use during adolescence represents a severe form of substance use disorder (SUD) and is associated with poorer clinical outcomes. Although family functioning, attachment insecurity, emotion regulation difficulties, and childhood trauma have each been linked to adolescent substance use, their relative contributions to polysubstance use remain unclear. Objectives: This study aimed to examine the associations between family functioning, attachment, emotion regulation (ER) difficulties, and childhood trauma in adolescents with SUD, with a focus on their roles in polysubstance use. We hypothesized that ER difficulties would independently predict polysubstance use after controlling for other variables and explored mediation (via attachment) and moderation (via peer attachment) effects. Methods: This cross-sectional study included 54 adolescents receiving inpatient treatment for SUD. Validated self-report measures assessed family functioning, attachment to parents and peers, emotion regulation difficulties, and childhood traumatic experiences. Polysubstance use was defined as the intentional use of two or more substances meeting diagnostic criteria within the past year. Associations were examined using partial correlations with false discovery rate correction and hierarchical logistic regression. Exploratory mediation and moderation analyses were conducted. Results: Emotion regulation difficulties survived as the only variable reaching threshold in exploratory analyses, although estimates were imprecise and should be interpreted cautiously. While healthier family functioning initially appeared protective, this association was attenuated when childhood trauma was included in the models. Family dysfunction was associated with insecure parental attachment and higher levels of emotional and physical abuse and neglect. Attachment variables neither independently predicted polysubstance use nor mediated or moderated the observed associations. Conclusions: Emotion regulation difficulties may be associated with polysubstance use in adolescents with SUD. Trauma exposure may undermine family-level protective effects, possibly pointing to the need for trauma-informed, emotion regulation–focused interventions in adolescent addiction treatment. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/10826084.2026.2651446
    Languages:
      – Code: eng
        Text: English
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        PageCount: 12
        StartPage: 1777
    Subjects:
      – SubjectFull: Substance abuse risk factors
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Self-evaluation
        Type: general
      – SubjectFull: Parents
        Type: general
      – SubjectFull: Blood testing
        Type: general
      – SubjectFull: Data analysis
        Type: general
      – SubjectFull: T-test (Statistics)
        Type: general
      – SubjectFull: Child abuse
        Type: general
      – SubjectFull: Alexithymia
        Type: general
      – SubjectFull: Affinity groups
        Type: general
      – SubjectFull: Attachment behavior
        Type: general
      – SubjectFull: Statistical sampling
        Type: general
      – SubjectFull: Fisher exact test
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      – SubjectFull: Probability theory
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      – SubjectFull: Logistic regression analysis
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      – SubjectFull: Family relations
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      – SubjectFull: Multivariate analysis
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      – SubjectFull: Chi-squared test
        Type: general
      – SubjectFull: Mann Whitney U Test
        Type: general
      – SubjectFull: Urinalysis
        Type: general
      – SubjectFull: Statistics
        Type: general
      – SubjectFull: Factor analysis
        Type: general
      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: Disease complications
        Type: general
      – SubjectFull: Adolescence
        Type: general
    Titles:
      – TitleFull: The Roles of Family Functioning, Attachment Status, Emotion Regulation Skills and Traumatic Experiences in Adolescents with Substance Use Disorder and Their Potential Effects on Polysubstance Use.
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              Text: 2026
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