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Retrospective Assessment of Adjacent Fracture Risks in Vertebroplasty, Kyphoplasty, and Bone‐Tumor Radiofrequency Ablation.

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Title: Retrospective Assessment of Adjacent Fracture Risks in Vertebroplasty, Kyphoplasty, and Bone‐Tumor Radiofrequency Ablation.
Authors: Sheen, Soun (AUTHOR), Hasan, Prit (AUTHOR), Sun, Xiaowen (AUTHOR), Wang, Jian (AUTHOR), Tatsui, Claudio (AUTHOR), Nouri, Kent (AUTHOR), Javed, Saba (AUTHOR)
Source: Pain Practice. Jul2026, Vol. 26 Issue 6, p1-10. 10p.
Subjects: Kyphoplasty, Risk assessment, Vertebroplasty, Bone density, Kruskal-Wallis Test, Fisher exact test, Vertebral fractures, Bone tumors, Radio frequency therapy, Compression fractures, Retrospective studies, Chi-squared test, Descriptive statistics, Surgical complications, Longitudinal method, Log-rank test, Kaplan-Meier estimator, Catheter ablation, Data analysis software, Proportional hazards models, Disease risk factors
Abstract: Introduction: Percutaneous vertebral augmentation is widely used to provide symptom relief for patients with painful vertebral compression fractures (VCFs), but adjacent fractures remain a known complication. This retrospective study evaluated the risk of adjacent vertebral fractures following different percutaneous vertebral augmentation techniques. Methods: A total of 985 encounters from 878 patients who underwent vertebroplasty, kyphoplasty, or bone tumor radiofrequency ablation (BT‐RFA) with cement augmentation were included. The primary outcome was incidence of postprocedural adjacent fractures. Associations with demographic and clinical factors including age, sex, BMI, pathologic fractures, bone density, imaging guidance, and number of treated levels were assessed. Statistical analyses included a generalized linear mixed model and Cox proportional hazards models clustered by patient. Results: Adjacent fracture occurred in 17.8% of encounters. BT‐RFA was associated with a significantly lower risk of adjacent fractures compared with kyphoplasty (HR: 0.54, 95% CI:0.36–0.81; p = 0.003) and vertebroplasty (HR: 0.40, 95% CI: 0.27–0.60; p < 0.0001). Multilevel vertebral augmentations increased fracture risk by 1.42‐fold, while pathologic fractures lowered the odds of adjacent fracture. No significant associations were found for age, BMI, sex, cement extravasation, or bone density. Conclusion: BT‐RFA combined with cement augmentation significantly reduced the risk of adjacent fractures compared to kyphoplasty or vertebroplasty. [ABSTRACT FROM AUTHOR]
Copyright of Pain Practice is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Retrospective Assessment of Adjacent Fracture Risks in Vertebroplasty, Kyphoplasty, and Bone‐Tumor Radiofrequency Ablation.
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– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Introduction: Percutaneous vertebral augmentation is widely used to provide symptom relief for patients with painful vertebral compression fractures (VCFs), but adjacent fractures remain a known complication. This retrospective study evaluated the risk of adjacent vertebral fractures following different percutaneous vertebral augmentation techniques. Methods: A total of 985 encounters from 878 patients who underwent vertebroplasty, kyphoplasty, or bone tumor radiofrequency ablation (BT‐RFA) with cement augmentation were included. The primary outcome was incidence of postprocedural adjacent fractures. Associations with demographic and clinical factors including age, sex, BMI, pathologic fractures, bone density, imaging guidance, and number of treated levels were assessed. Statistical analyses included a generalized linear mixed model and Cox proportional hazards models clustered by patient. Results: Adjacent fracture occurred in 17.8% of encounters. BT‐RFA was associated with a significantly lower risk of adjacent fractures compared with kyphoplasty (HR: 0.54, 95% CI:0.36–0.81; p = 0.003) and vertebroplasty (HR: 0.40, 95% CI: 0.27–0.60; p &lt; 0.0001). Multilevel vertebral augmentations increased fracture risk by 1.42‐fold, while pathologic fractures lowered the odds of adjacent fracture. No significant associations were found for age, BMI, sex, cement extravasation, or bone density. Conclusion: BT‐RFA combined with cement augmentation significantly reduced the risk of adjacent fractures compared to kyphoplasty or vertebroplasty. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: &lt;i&gt;Copyright of Pain Practice is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=195154842
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/papr.70182
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 10
        StartPage: 1
    Subjects:
      – SubjectFull: Kyphoplasty
        Type: general
      – SubjectFull: Risk assessment
        Type: general
      – SubjectFull: Vertebroplasty
        Type: general
      – SubjectFull: Bone density
        Type: general
      – SubjectFull: Kruskal-Wallis Test
        Type: general
      – SubjectFull: Fisher exact test
        Type: general
      – SubjectFull: Vertebral fractures
        Type: general
      – SubjectFull: Bone tumors
        Type: general
      – SubjectFull: Radio frequency therapy
        Type: general
      – SubjectFull: Compression fractures
        Type: general
      – SubjectFull: Retrospective studies
        Type: general
      – SubjectFull: Chi-squared test
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Surgical complications
        Type: general
      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Log-rank test
        Type: general
      – SubjectFull: Kaplan-Meier estimator
        Type: general
      – SubjectFull: Catheter ablation
        Type: general
      – SubjectFull: Data analysis software
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      – SubjectFull: Proportional hazards models
        Type: general
      – SubjectFull: Disease risk factors
        Type: general
    Titles:
      – TitleFull: Retrospective Assessment of Adjacent Fracture Risks in Vertebroplasty, Kyphoplasty, and Bone‐Tumor Radiofrequency Ablation.
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            – D: 01
              M: 07
              Text: Jul2026
              Type: published
              Y: 2026
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