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Sick Leave and Drug Use After Endovascular Versus Surgical Treatment of Unruptured Intracranial Aneurysms: A Nationwide Registry‐Based Study.

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Title: Sick Leave and Drug Use After Endovascular Versus Surgical Treatment of Unruptured Intracranial Aneurysms: A Nationwide Registry‐Based Study.
Authors: Thurin, Erik (AUTHOR), de Dios, Eddie (AUTHOR), Solheim, Ole (AUTHOR), Skoglund, Thomas (AUTHOR), Salvesen, Øyvind (AUTHOR), Jakola, Asgeir S. (AUTHOR), Chauhan, Anjali (AUTHOR)
Source: Acta Neurologica Scandinavica. 7/8/2026, Vol. 2026, p1-11. 11p.
Subjects: Sick leave, Drug utilization, Endovascular surgery, Antidepressants, Intracranial aneurysms, Surgery, Sedatives, Pain medicine
Abstract: Background: Both endovascular and surgical treatments are often reasonable alternatives in the treatment of unruptured intracranial aneurysms (UIAs). Studies on how these alternatives affect the well‐being of patients beyond rebleeding and mortality are surprisingly scarce. We therefore aimed to study the rate of sick leave and use of antidepressant, sedative, and pain‐relieving medication following surgical or endovascular treatment of UIA. Methods: After identifying all 1659 patients treated endovascularly (n = 1021) or surgically (n = 638) for UIAs in the period from 2010 to 2020, we linked several population‐based registries using SQL software to determine the use of medications and sick leave. The index date was defined as the day of treatment. Findings: At 1 month after treatment, sick leave compensation was less frequent (p < 0.001) in the endovascularly treated group (55.2%) compared with the surgically treated group (82.5%), but 2 years after the intervention, there was no meaningful difference between groups. Use of opioids was higher during the first month in the surgically treated group. Use of antidepressants and sedatives did not differ significantly. Interpretation: Sick leave was more common in patients treated for UIAs than age‐matched controls, both 2 years before and 2 years after treatment. Endovascularly treated patients with UIAs have a lower rate of sick leave during the first months after treatment and a lower rate of opioid use during the first month after treatment, compared with surgically treated patients. [ABSTRACT FROM AUTHOR]
Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Label: Title
  Group: Ti
  Data: Sick Leave and Drug Use After Endovascular Versus Surgical Treatment of Unruptured Intracranial Aneurysms: A Nationwide Registry‐Based Study.
– Name: Author
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Thurin%2C+Erik%22&quot;&gt;Thurin, Erik&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22de+Dios%2C+Eddie%22&quot;&gt;de Dios, Eddie&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Solheim%2C+Ole%22&quot;&gt;Solheim, Ole&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Skoglund%2C+Thomas%22&quot;&gt;Skoglund, Thomas&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Salvesen%2C+&#216;yvind%22&quot;&gt;Salvesen, &#216;yvind&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Jakola%2C+Asgeir+S%2E%22&quot;&gt;Jakola, Asgeir S.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Chauhan%2C+Anjali%22&quot;&gt;Chauhan, Anjali&lt;/searchLink&gt; (AUTHOR)
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Acta+Neurologica+Scandinavica%22&quot;&gt;Acta Neurologica Scandinavica&lt;/searchLink&gt;. 7/8/2026, Vol. 2026, p1-11. 11p.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Sick+leave%22&quot;&gt;Sick leave&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Drug+utilization%22&quot;&gt;Drug utilization&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Endovascular+surgery%22&quot;&gt;Endovascular surgery&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Antidepressants%22&quot;&gt;Antidepressants&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Intracranial+aneurysms%22&quot;&gt;Intracranial aneurysms&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Surgery%22&quot;&gt;Surgery&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Sedatives%22&quot;&gt;Sedatives&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Pain+medicine%22&quot;&gt;Pain medicine&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Both endovascular and surgical treatments are often reasonable alternatives in the treatment of unruptured intracranial aneurysms (UIAs). Studies on how these alternatives affect the well‐being of patients beyond rebleeding and mortality are surprisingly scarce. We therefore aimed to study the rate of sick leave and use of antidepressant, sedative, and pain‐relieving medication following surgical or endovascular treatment of UIA. Methods: After identifying all 1659 patients treated endovascularly (n = 1021) or surgically (n = 638) for UIAs in the period from 2010 to 2020, we linked several population‐based registries using SQL software to determine the use of medications and sick leave. The index date was defined as the day of treatment. Findings: At 1 month after treatment, sick leave compensation was less frequent (p &lt; 0.001) in the endovascularly treated group (55.2%) compared with the surgically treated group (82.5%), but 2 years after the intervention, there was no meaningful difference between groups. Use of opioids was higher during the first month in the surgically treated group. Use of antidepressants and sedatives did not differ significantly. Interpretation: Sick leave was more common in patients treated for UIAs than age‐matched controls, both 2 years before and 2 years after treatment. Endovascularly treated patients with UIAs have a lower rate of sick leave during the first months after treatment and a lower rate of opioid use during the first month after treatment, compared with surgically treated patients. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: &lt;i&gt;Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1155/ane/6565839
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 11
        StartPage: 1
    Subjects:
      – SubjectFull: Sick leave
        Type: general
      – SubjectFull: Drug utilization
        Type: general
      – SubjectFull: Endovascular surgery
        Type: general
      – SubjectFull: Antidepressants
        Type: general
      – SubjectFull: Intracranial aneurysms
        Type: general
      – SubjectFull: Surgery
        Type: general
      – SubjectFull: Sedatives
        Type: general
      – SubjectFull: Pain medicine
        Type: general
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      – TitleFull: Sick Leave and Drug Use After Endovascular Versus Surgical Treatment of Unruptured Intracranial Aneurysms: A Nationwide Registry‐Based Study.
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              Text: 7/8/2026
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              Y: 2026
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