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Dental Caries of Individuals with Autism Spectrum Disorder (ASD): A Systematic Review and Meta-Analysis.

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Title: Dental Caries of Individuals with Autism Spectrum Disorder (ASD): A Systematic Review and Meta-Analysis.
Authors: da Motta, Thiago Peixoto (AUTHOR), da Mota, Débora Guedes (AUTHOR), Bitencourt, Fernando Valentim (AUTHOR), Jardim, Patrick Felix (AUTHOR), Abreu, Lucas Guimarães (AUTHOR), Zina, Lívia Guimarães (AUTHOR), de Abreu, Mauro Henrique Nogueira Guimarães (AUTHOR), Vargas-Ferreira, Fabiana (AUTHOR)
Source: Journal of Autism & Developmental Disorders. Jul2026, Vol. 56 Issue 7, p2735-2751. 17p.
Subjects: Asperger's syndrome in children, Risk assessment, Medical information storage & retrieval systems, Autism in children, Children with disabilities, Grey literature, Research funding, Meta-analysis, Disease prevalence, Descriptive statistics, Asperger's syndrome in adolescence, Systematic reviews, MEDLINE, Odds ratio, Inferential statistics, Dental caries, Data analysis software, Online information services, Confidence intervals, Autism in adolescence, Oral health, Disease risk factors
Abstract: This systematic review and meta-analysis aimed to assess and compare the prevalence of dental caries in children and adolescents with and without ASD and identify associated factors. Following the PRISMA guidelines, a comprehensive literature search was conducted across multiple databases, yielding 2,103 studies, from which 25 met inclusion criteria. The primary outcome measure was caries prevalence, analyzed through clinical assessments. Risk of bias was evaluated using an adapted Newcastle–Ottawa Scale. Statistical analysis was performed with Review Manager, using random-effects models to account for heterogeneity, which was assessed with I2. Meta-analyses revealed no significant differences between groups for most caries indicators, such as DMFT and dmft indices. However, the mean Caries Per Surface (DMFS) index was significantly higher in ASD patients, suggesting greater caries severity. Our study found a significant difference in dental caries severity between children and adolescents with Autism Spectrum Disorder (ASD) and those without ASD, through the DMFS index. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Autism & Developmental Disorders is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Dental Caries of Individuals with Autism Spectrum Disorder (ASD): A Systematic Review and Meta-Analysis.
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  Data: <searchLink fieldCode="AR" term="%22da+Motta%2C+Thiago+Peixoto%22">da Motta, Thiago Peixoto</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22da+Mota%2C+Débora+Guedes%22">da Mota, Débora Guedes</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bitencourt%2C+Fernando+Valentim%22">Bitencourt, Fernando Valentim</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jardim%2C+Patrick+Felix%22">Jardim, Patrick Felix</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Abreu%2C+Lucas+Guimarães%22">Abreu, Lucas Guimarães</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zina%2C+Lívia+Guimarães%22">Zina, Lívia Guimarães</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22de+Abreu%2C+Mauro+Henrique+Nogueira+Guimarães%22">de Abreu, Mauro Henrique Nogueira Guimarães</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Vargas-Ferreira%2C+Fabiana%22">Vargas-Ferreira, Fabiana</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Autism+%26+Developmental+Disorders%22">Journal of Autism & Developmental Disorders</searchLink>. Jul2026, Vol. 56 Issue 7, p2735-2751. 17p.
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– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: This systematic review and meta-analysis aimed to assess and compare the prevalence of dental caries in children and adolescents with and without ASD and identify associated factors. Following the PRISMA guidelines, a comprehensive literature search was conducted across multiple databases, yielding 2,103 studies, from which 25 met inclusion criteria. The primary outcome measure was caries prevalence, analyzed through clinical assessments. Risk of bias was evaluated using an adapted Newcastle–Ottawa Scale. Statistical analysis was performed with Review Manager, using random-effects models to account for heterogeneity, which was assessed with I2. Meta-analyses revealed no significant differences between groups for most caries indicators, such as DMFT and dmft indices. However, the mean Caries Per Surface (DMFS) index was significantly higher in ASD patients, suggesting greater caries severity. Our study found a significant difference in dental caries severity between children and adolescents with Autism Spectrum Disorder (ASD) and those without ASD, through the DMFS index. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Journal of Autism & Developmental Disorders is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1007/s10803-025-06754-7
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        Text: English
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        StartPage: 2735
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      – SubjectFull: Risk assessment
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      – SubjectFull: Medical information storage & retrieval systems
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