Rushton bodies in inflamed cysts: Histologic evidence supporting dual-origin hypothesis – A report of two cases.

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Title: Rushton bodies in inflamed cysts: Histologic evidence supporting dual-origin hypothesis – A report of two cases.
Authors: Divya, Bose (AUTHOR), Krishnan, Rajkumar (AUTHOR), Annasamy, Ramesh Kumar (AUTHOR), Sundararajan, Kavina (AUTHOR), Manoj, Akshay (AUTHOR)
Source: Journal of Oral Research & Review. Jul-Dec2026, Vol. 18 Issue 2, p205-208. 4p.
Subjects: Radicular cyst, Inflammation, Histology, Hypothesis, Odontogenic cysts
Abstract: Rushton bodies (RBs) are eosinophilic, hyaline structures often seen in odontogenic cysts; however, their origin remains a subject of debate. This report documents the histologic presence of RBs in two distinct cystic lesions – a radicular cyst and an odontogenic keratocyst (OKC) – both exhibiting varying degrees of inflammation. In the radicular cyst, RBs were predominantly located near areas of hemorrhage and chronic inflammation. In contrast, RBs within the OKC were closely associated with the epithelial lining. These differential patterns suggest that RB formation may arise from both epithelial secretions and blood-derived components, modulated by the local inflammatory microenvironment. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
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Abstract:Rushton bodies (RBs) are eosinophilic, hyaline structures often seen in odontogenic cysts; however, their origin remains a subject of debate. This report documents the histologic presence of RBs in two distinct cystic lesions – a radicular cyst and an odontogenic keratocyst (OKC) – both exhibiting varying degrees of inflammation. In the radicular cyst, RBs were predominantly located near areas of hemorrhage and chronic inflammation. In contrast, RBs within the OKC were closely associated with the epithelial lining. These differential patterns suggest that RB formation may arise from both epithelial secretions and blood-derived components, modulated by the local inflammatory microenvironment. [ABSTRACT FROM AUTHOR]
ISSN:22494987
DOI:10.4103/jorr.jorr_190_25