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Rushton bodies in inflamed cysts: Histologic evidence supporting dual-origin hypothesis – A report of two cases.

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Title: Rushton bodies in inflamed cysts: Histologic evidence supporting dual-origin hypothesis – A report of two cases.
Authors: Divya, Bose (AUTHOR), Krishnan, Rajkumar (AUTHOR), Annasamy, Ramesh Kumar (AUTHOR), Sundararajan, Kavina (AUTHOR), Manoj, Akshay (AUTHOR)
Source: Journal of Oral Research & Review. Jul-Dec2026, Vol. 18 Issue 2, p205-208. 4p.
Subjects: Radicular cyst, Inflammation, Histology, Hypothesis, Odontogenic cysts
Abstract: Rushton bodies (RBs) are eosinophilic, hyaline structures often seen in odontogenic cysts; however, their origin remains a subject of debate. This report documents the histologic presence of RBs in two distinct cystic lesions – a radicular cyst and an odontogenic keratocyst (OKC) – both exhibiting varying degrees of inflammation. In the radicular cyst, RBs were predominantly located near areas of hemorrhage and chronic inflammation. In contrast, RBs within the OKC were closely associated with the epithelial lining. These differential patterns suggest that RB formation may arise from both epithelial secretions and blood-derived components, modulated by the local inflammatory microenvironment. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Oral Research & Review is the property of Wolters Kluwer India Pvt Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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PubType: Academic Journal
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  Label: Title
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  Data: Rushton bodies in inflamed cysts: Histologic evidence supporting dual-origin hypothesis – A report of two cases.
– Name: Author
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  Data: <searchLink fieldCode="AR" term="%22Divya%2C+Bose%22">Divya, Bose</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Krishnan%2C+Rajkumar%22">Krishnan, Rajkumar</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Annasamy%2C+Ramesh+Kumar%22">Annasamy, Ramesh Kumar</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sundararajan%2C+Kavina%22">Sundararajan, Kavina</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Manoj%2C+Akshay%22">Manoj, Akshay</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Oral+Research+%26+Review%22">Journal of Oral Research & Review</searchLink>. Jul-Dec2026, Vol. 18 Issue 2, p205-208. 4p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Radicular+cyst%22">Radicular cyst</searchLink><br /><searchLink fieldCode="DE" term="%22Inflammation%22">Inflammation</searchLink><br /><searchLink fieldCode="DE" term="%22Histology%22">Histology</searchLink><br /><searchLink fieldCode="DE" term="%22Hypothesis%22">Hypothesis</searchLink><br /><searchLink fieldCode="DE" term="%22Odontogenic+cysts%22">Odontogenic cysts</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Rushton bodies (RBs) are eosinophilic, hyaline structures often seen in odontogenic cysts; however, their origin remains a subject of debate. This report documents the histologic presence of RBs in two distinct cystic lesions – a radicular cyst and an odontogenic keratocyst (OKC) – both exhibiting varying degrees of inflammation. In the radicular cyst, RBs were predominantly located near areas of hemorrhage and chronic inflammation. In contrast, RBs within the OKC were closely associated with the epithelial lining. These differential patterns suggest that RB formation may arise from both epithelial secretions and blood-derived components, modulated by the local inflammatory microenvironment. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Oral Research & Review is the property of Wolters Kluwer India Pvt Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.4103/jorr.jorr_190_25
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 4
        StartPage: 205
    Subjects:
      – SubjectFull: Radicular cyst
        Type: general
      – SubjectFull: Inflammation
        Type: general
      – SubjectFull: Histology
        Type: general
      – SubjectFull: Hypothesis
        Type: general
      – SubjectFull: Odontogenic cysts
        Type: general
    Titles:
      – TitleFull: Rushton bodies in inflamed cysts: Histologic evidence supporting dual-origin hypothesis – A report of two cases.
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            NameFull: Divya, Bose
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            NameFull: Krishnan, Rajkumar
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            NameFull: Annasamy, Ramesh Kumar
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            NameFull: Sundararajan, Kavina
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            NameFull: Manoj, Akshay
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          Dates:
            – D: 01
              M: 07
              Text: Jul-Dec2026
              Type: published
              Y: 2026
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            – TitleFull: Journal of Oral Research & Review
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