Challenges in rehabilitation of oncological defect of the mandible – A comprehensive review.

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Title: Challenges in rehabilitation of oncological defect of the mandible – A comprehensive review.
Authors: Manoj, Neelima (AUTHOR), Chidambaranathan, Ahila Singaravel (AUTHOR), Balasubramanium, Muthukumar (AUTHOR)
Source: Journal of Oral Research & Review. Jul-Dec2026, Vol. 18 Issue 2, p214-220. 7p.
Subjects: Prosthodontics, Free flaps, Jaw diseases, Cosmetic dentistry, Mandible surgery, Osseointegrated dental implants
Abstract: Prosthetic rehabilitation following mandibulectomy presents unique challenges due to the complexity of restoring both form and function in the affected region. An electronic search was conducted across four databases PubMed, Google Scholar, Cochrane Library, and Science Direct in the English language from January 1995 to June 2024 using the key terms mandibulectomy OR hemi-mandibulectomy OR Cantor and Curtis OR Panel OR Guiding flange AND denture OR prosthetic AND flap OR surgery OR prosthetic rehabilitation. In addition, a hand search was performed in the institutional library on Journal of Prosthetic Dentistry , Journal of Indian Prosthodontic Society , Journal of Prosthodontics , International Journal of Prosthodontics and Indian Journal of Prosthodontic Research. This review concluded that the loss of mandibular continuity impacts mastication, speech, esthetics, and psychological well-being. Successful rehabilitation requires careful consideration of the extent of resection, soft-tissue support, and the presence of residual structures. Advances in surgical techniques, such as free flap reconstructions and the integration of osseo-integrated implants, have enhanced outcomes but also introduced technical intricacies. Patient-specific factors, such as systemic health and postoperative complications, further influence the prosthetic approach. Rehabilitation of mandibular defect started with correction of deviations and restores the esthetics which improves the quality of life of patient. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Oral Research & Review is the property of Wolters Kluwer India Pvt Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Challenges in rehabilitation of oncological defect of the mandible – A comprehensive review.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Manoj%2C+Neelima%22">Manoj, Neelima</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chidambaranathan%2C+Ahila+Singaravel%22">Chidambaranathan, Ahila Singaravel</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Balasubramanium%2C+Muthukumar%22">Balasubramanium, Muthukumar</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Oral+Research+%26+Review%22">Journal of Oral Research & Review</searchLink>. Jul-Dec2026, Vol. 18 Issue 2, p214-220. 7p.
– Name: Subject
  Label: Subjects
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  Data: <searchLink fieldCode="DE" term="%22Prosthodontics%22">Prosthodontics</searchLink><br /><searchLink fieldCode="DE" term="%22Free+flaps%22">Free flaps</searchLink><br /><searchLink fieldCode="DE" term="%22Jaw+diseases%22">Jaw diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Cosmetic+dentistry%22">Cosmetic dentistry</searchLink><br /><searchLink fieldCode="DE" term="%22Mandible+surgery%22">Mandible surgery</searchLink><br /><searchLink fieldCode="DE" term="%22Osseointegrated+dental+implants%22">Osseointegrated dental implants</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Prosthetic rehabilitation following mandibulectomy presents unique challenges due to the complexity of restoring both form and function in the affected region. An electronic search was conducted across four databases PubMed, Google Scholar, Cochrane Library, and Science Direct in the English language from January 1995 to June 2024 using the key terms mandibulectomy OR hemi-mandibulectomy OR Cantor and Curtis OR Panel OR Guiding flange AND denture OR prosthetic AND flap OR surgery OR prosthetic rehabilitation. In addition, a hand search was performed in the institutional library on Journal of Prosthetic Dentistry , Journal of Indian Prosthodontic Society , Journal of Prosthodontics , International Journal of Prosthodontics and Indian Journal of Prosthodontic Research. This review concluded that the loss of mandibular continuity impacts mastication, speech, esthetics, and psychological well-being. Successful rehabilitation requires careful consideration of the extent of resection, soft-tissue support, and the presence of residual structures. Advances in surgical techniques, such as free flap reconstructions and the integration of osseo-integrated implants, have enhanced outcomes but also introduced technical intricacies. Patient-specific factors, such as systemic health and postoperative complications, further influence the prosthetic approach. Rehabilitation of mandibular defect started with correction of deviations and restores the esthetics which improves the quality of life of patient. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Oral Research & Review is the property of Wolters Kluwer India Pvt Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=195473420
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.4103/jorr.jorr_36_25
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      – Code: eng
        Text: English
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      – SubjectFull: Prosthodontics
        Type: general
      – SubjectFull: Free flaps
        Type: general
      – SubjectFull: Jaw diseases
        Type: general
      – SubjectFull: Cosmetic dentistry
        Type: general
      – SubjectFull: Mandible surgery
        Type: general
      – SubjectFull: Osseointegrated dental implants
        Type: general
    Titles:
      – TitleFull: Challenges in rehabilitation of oncological defect of the mandible – A comprehensive review.
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            NameFull: Manoj, Neelima
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            NameFull: Chidambaranathan, Ahila Singaravel
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            NameFull: Balasubramanium, Muthukumar
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          Dates:
            – D: 01
              M: 07
              Text: Jul-Dec2026
              Type: published
              Y: 2026
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            – TitleFull: Journal of Oral Research & Review
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