Arabic Language Autism Diagnostic Interview (ALADIN): A Validation Study.

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Title: Arabic Language Autism Diagnostic Interview (ALADIN): A Validation Study.
Authors: Nasir, Arwa K. (AUTHOR), Masri, Amira T. (AUTHOR), Shaheen, Saja (AUTHOR), Sayles, Harlan (AUTHOR), Nasir, Laeth (AUTHOR)
Source: Journal of Autism & Developmental Disorders. Aug2026, Vol. 56 Issue 8, p3253-3261. 9p.
Subjects: Diagnosis of autism, Research funding, Receiver operating characteristic curves, T-test (Statistics), Research methodology evaluation, Culture, Fisher exact test, Interviewing, Retrospective studies, Descriptive statistics, Experimental design, Arabs, Research methodology, Case-control method, Medical records, Acquisition of data, Asperger's syndrome, Data analysis software, Sensitivity & specificity (Statistics), Children
Geographic Terms: Jordan
Abstract: There is a gap in autism research from Low- and Middle-Income Countries (LMIC) where most children with autism live. This has contributed to a lack of culturally validated diagnostic instruments for autism and is a major barrier to early diagnosis, intervention, and research. The Arabic Language Autism Diagnostic Inventory (ALADIN) was developed based on the DSM-5 criteria and adapted to Arabic language and culture using primary source data. The aim of this study was to validate the Arabic Language Autism Diagnostic Inventory for the diagnostic evaluation of autism. A case–control study design was used to test the instrument for sensitivity and specificity for diagnosis of autism in children 2–5 years of age. Parents of 48 children with autism and 152 neurotypical children in Jordan completed the ALADIN. Demographic information from the participants in each group was summarized, and a Receiver Operating Curve (ROC) was fit to the data. A total score of 24 on the ALADIN had 77% sensitivity and 98% specificity for autism. The area under the curve (AUC) was 0.976, indicating strong performance in identifying children with autism. The ALADIN is the first instrument created specifically for Arab populations and is informed by cultural and linguistic data from the target population. Initial validation shows it has high diagnostic specificity for autism. Culturally informed instruments can improve access to early diagnosis and intervention and enhance autism research to improve care and outcomes in global populations. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Autism & Developmental Disorders is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Arabic Language Autism Diagnostic Interview (ALADIN): A Validation Study.
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  Data: <searchLink fieldCode="AR" term="%22Nasir%2C+Arwa+K%2E%22">Nasir, Arwa K.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Masri%2C+Amira+T%2E%22">Masri, Amira T.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Shaheen%2C+Saja%22">Shaheen, Saja</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sayles%2C+Harlan%22">Sayles, Harlan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nasir%2C+Laeth%22">Nasir, Laeth</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Autism+%26+Developmental+Disorders%22">Journal of Autism & Developmental Disorders</searchLink>. Aug2026, Vol. 56 Issue 8, p3253-3261. 9p.
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  Data: <searchLink fieldCode="DE" term="%22Diagnosis+of+autism%22">Diagnosis of autism</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Receiver+operating+characteristic+curves%22">Receiver operating characteristic curves</searchLink><br /><searchLink fieldCode="DE" term="%22T-test+%28Statistics%29%22">T-test (Statistics)</searchLink><br /><searchLink fieldCode="DE" term="%22Research+methodology+evaluation%22">Research methodology evaluation</searchLink><br /><searchLink fieldCode="DE" term="%22Culture%22">Culture</searchLink><br /><searchLink fieldCode="DE" term="%22Fisher+exact+test%22">Fisher exact test</searchLink><br /><searchLink fieldCode="DE" term="%22Interviewing%22">Interviewing</searchLink><br /><searchLink fieldCode="DE" term="%22Retrospective+studies%22">Retrospective studies</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Experimental+design%22">Experimental design</searchLink><br /><searchLink fieldCode="DE" term="%22Arabs%22">Arabs</searchLink><br /><searchLink fieldCode="DE" term="%22Research+methodology%22">Research methodology</searchLink><br /><searchLink fieldCode="DE" term="%22Case-control+method%22">Case-control method</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+records%22">Medical records</searchLink><br /><searchLink fieldCode="DE" term="%22Acquisition+of+data%22">Acquisition of data</searchLink><br /><searchLink fieldCode="DE" term="%22Asperger's+syndrome%22">Asperger's syndrome</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis+software%22">Data analysis software</searchLink><br /><searchLink fieldCode="DE" term="%22Sensitivity+%26+specificity+%28Statistics%29%22">Sensitivity & specificity (Statistics)</searchLink><br /><searchLink fieldCode="DE" term="%22Children%22">Children</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Jordan%22">Jordan</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: There is a gap in autism research from Low- and Middle-Income Countries (LMIC) where most children with autism live. This has contributed to a lack of culturally validated diagnostic instruments for autism and is a major barrier to early diagnosis, intervention, and research. The Arabic Language Autism Diagnostic Inventory (ALADIN) was developed based on the DSM-5 criteria and adapted to Arabic language and culture using primary source data. The aim of this study was to validate the Arabic Language Autism Diagnostic Inventory for the diagnostic evaluation of autism. A case–control study design was used to test the instrument for sensitivity and specificity for diagnosis of autism in children 2–5 years of age. Parents of 48 children with autism and 152 neurotypical children in Jordan completed the ALADIN. Demographic information from the participants in each group was summarized, and a Receiver Operating Curve (ROC) was fit to the data. A total score of 24 on the ALADIN had 77% sensitivity and 98% specificity for autism. The area under the curve (AUC) was 0.976, indicating strong performance in identifying children with autism. The ALADIN is the first instrument created specifically for Arab populations and is informed by cultural and linguistic data from the target population. Initial validation shows it has high diagnostic specificity for autism. Culturally informed instruments can improve access to early diagnosis and intervention and enhance autism research to improve care and outcomes in global populations. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Journal of Autism & Developmental Disorders is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1007/s10803-025-06797-w
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      – Code: eng
        Text: English
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        PageCount: 9
        StartPage: 3253
    Subjects:
      – SubjectFull: Diagnosis of autism
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Receiver operating characteristic curves
        Type: general
      – SubjectFull: T-test (Statistics)
        Type: general
      – SubjectFull: Research methodology evaluation
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      – SubjectFull: Culture
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      – SubjectFull: Fisher exact test
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      – SubjectFull: Interviewing
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      – SubjectFull: Retrospective studies
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Experimental design
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      – SubjectFull: Arabs
        Type: general
      – SubjectFull: Research methodology
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      – SubjectFull: Case-control method
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      – SubjectFull: Sensitivity & specificity (Statistics)
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      – SubjectFull: Children
        Type: general
      – SubjectFull: Jordan
        Type: general
    Titles:
      – TitleFull: Arabic Language Autism Diagnostic Interview (ALADIN): A Validation Study.
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            NameFull: Nasir, Arwa K.
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              M: 08
              Text: Aug2026
              Type: published
              Y: 2026
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