Verbal and Visuospatial Working Memory Performance During the CO2 Challenge Model of Anxiety.
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| Title: | Verbal and Visuospatial Working Memory Performance During the CO |
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| Authors: | Dunger, Warren (AUTHOR), Edwards, Marc (AUTHOR), Board, Alex (AUTHOR), Garner, Matthew (AUTHOR) |
| Source: | Human Psychopharmacology: Clinical & Experimental. Jul2026, Vol. 41 Issue 4, p1-9. 9p. |
| Abstract: | Objective: Anxiety influences working memory performance, but the effects on clinical neuropsychological assessments of working memory are not well known. Methods: We examined the effect of anxiety, induced using the 7.5% carbon dioxide model of anxiety on standardized clinical neuropsychological tests of working memory and executive function in a single‐blind, placebo‐controlled, randomized, crossover within‐subjects design. Results: The CO2‐challenge reduced spatial working memory performance and verbal working memory performance accuracy when task demands were high. The CO2‐challenge increased effort and reduced processing efficiency across all verbal and spatial working memory tasks. Conclusions: The CO2‐challenge resulted in significant reductions in working memory performance and processing efficiency. These results encourage the routine assessment of anxiety when administering and interpreting neuropsychological measures of working memory function in clinical practice. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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