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Mediators of Change in Cognitive Behavioral and Mindfulness-Based Online-Interventions for Hypoactive Sexual Desire Dysfunction in Women.

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Title: Mediators of Change in Cognitive Behavioral and Mindfulness-Based Online-Interventions for Hypoactive Sexual Desire Dysfunction in Women.
Authors: Velten, Julia (AUTHOR), Hirschfeld, Gerrit (AUTHOR), Margraf, Jürgen (AUTHOR)
Source: Journal of Sex Research. Oct2026, Vol. 63 Issue 8, p1395-1408. 14p.
Subjects: Hypoactive sexual desire disorder, Self-compassion, Patients, Cognitive therapy, Psychotherapy, Rumination (Cognition), Mathematical variables, Mindfulness-based cognitive therapy
Abstract: Low sexual desire is a common sexual problem among women. When it is accompanied by significant personal distress, it may be diagnosed as hypoactive sexual desire dysfunction (HSDD). Both cognitive behavioral therapy (CBT) and mindfulness-based therapy (MBT) are effective treatments for HSDD when delivered in person or online. In this randomized controlled treatment study, CBT and MBT consisted of eight guided self-help modules delivered online, and participants completed measures at pretreatment and after 3, 6, and 12 months. Nine variables were examined as potential mediators of treatment outcomes (i.e., sexual desire and sexual distress), namely mindfulness, self-compassion, rumination, body connection, self-consciousness, relationship satisfaction, sexual communication, depression, and anxiety. In total, 212 women diagnosed with HSDD were randomized to either CBT or MBT (Mage = 36.3, SD = 10.2). Improvements in self-compassion, rumination, body connection, and self-consciousness partially mediated treatment outcomes in at least one of the treatment groups. Mediation effects were mostly small, explaining up to 15% of the total effects. No systematic differences in mediation pathways between CBT and MBT were found. These findings emphasize the importance of emotion regulation, metacognitive processes, and embodiment for the effective treatment of HSDD. Future research should refine treatment components to enhance efficacy and ensure that psychological interventions adequately address common concerns among women with HSDD. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Sex Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Mediators of Change in Cognitive Behavioral and Mindfulness-Based Online-Interventions for Hypoactive Sexual Desire Dysfunction in Women.
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  Data: <searchLink fieldCode="AR" term="%22Velten%2C+Julia%22">Velten, Julia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hirschfeld%2C+Gerrit%22">Hirschfeld, Gerrit</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Margraf%2C+Jürgen%22">Margraf, Jürgen</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Sex+Research%22">Journal of Sex Research</searchLink>. Oct2026, Vol. 63 Issue 8, p1395-1408. 14p.
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  Data: <searchLink fieldCode="DE" term="%22Hypoactive+sexual+desire+disorder%22">Hypoactive sexual desire disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Self-compassion%22">Self-compassion</searchLink><br /><searchLink fieldCode="DE" term="%22Patients%22">Patients</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+therapy%22">Cognitive therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Psychotherapy%22">Psychotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Rumination+%28Cognition%29%22">Rumination (Cognition)</searchLink><br /><searchLink fieldCode="DE" term="%22Mathematical+variables%22">Mathematical variables</searchLink><br /><searchLink fieldCode="DE" term="%22Mindfulness-based+cognitive+therapy%22">Mindfulness-based cognitive therapy</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Low sexual desire is a common sexual problem among women. When it is accompanied by significant personal distress, it may be diagnosed as hypoactive sexual desire dysfunction (HSDD). Both cognitive behavioral therapy (CBT) and mindfulness-based therapy (MBT) are effective treatments for HSDD when delivered in person or online. In this randomized controlled treatment study, CBT and MBT consisted of eight guided self-help modules delivered online, and participants completed measures at pretreatment and after 3, 6, and 12 months. Nine variables were examined as potential mediators of treatment outcomes (i.e., sexual desire and sexual distress), namely mindfulness, self-compassion, rumination, body connection, self-consciousness, relationship satisfaction, sexual communication, depression, and anxiety. In total, 212 women diagnosed with HSDD were randomized to either CBT or MBT (Mage = 36.3, SD = 10.2). Improvements in self-compassion, rumination, body connection, and self-consciousness partially mediated treatment outcomes in at least one of the treatment groups. Mediation effects were mostly small, explaining up to 15% of the total effects. No systematic differences in mediation pathways between CBT and MBT were found. These findings emphasize the importance of emotion regulation, metacognitive processes, and embodiment for the effective treatment of HSDD. Future research should refine treatment components to enhance efficacy and ensure that psychological interventions adequately address common concerns among women with HSDD. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Journal of Sex Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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        Value: 10.1080/00224499.2025.2585522
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      – Code: eng
        Text: English
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        PageCount: 14
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        Type: general
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      – SubjectFull: Psychotherapy
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      – SubjectFull: Mathematical variables
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      – SubjectFull: Mindfulness-based cognitive therapy
        Type: general
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      – TitleFull: Mediators of Change in Cognitive Behavioral and Mindfulness-Based Online-Interventions for Hypoactive Sexual Desire Dysfunction in Women.
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            NameFull: Velten, Julia
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            NameFull: Hirschfeld, Gerrit
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            NameFull: Margraf, Jürgen
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              M: 10
              Text: Oct2026
              Type: published
              Y: 2026
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