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Sociodemographic Factors Associated with Opioid Agonist Treatment Receipt and Retention at an Integrated Safety-Net Health System.

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Title: Sociodemographic Factors Associated with Opioid Agonist Treatment Receipt and Retention at an Integrated Safety-Net Health System.
Authors: Tillman, Alexandra R. (AUTHOR), Braun, Hannan M. (AUTHOR), Christine, Paul J. (AUTHOR), Denzer, Brittany (AUTHOR), Loh, Ryan (AUTHOR), Bender, Brooke (AUTHOR), Bacon, Emily (AUTHOR)
Source: Substance Use & Misuse. 2026, Vol. 61 Issue 13, p2264-2272. 9p.
Subjects: Methadone treatment programs, Clinical drug trials, Substance abuse, Patient compliance, Dual diagnosis, Mathematical variables, Therapeutics, Health status indicators, Safety-net health care providers, African Americans, Multiple regression analysis, Mental illness, Central nervous system stimulants, Continuum of care, Descriptive statistics, Age distribution, Retrospective studies, Attitude (Psychology), Race, Alcohol-induced disorders, Odds ratio, Narcotics, Physician practice patterns, Medical records, Acquisition of data, Research, Sociodemographic factors, Opioid epidemic, Health equity, Comparative studies, Confidence intervals, Buprenorphine, Patients' attitudes, Patient participation, Integrated health care delivery, Drug abusers, Comorbidity
Geographic Terms: Colorado
Abstract: Introduction: Sociodemographic differences in opioid use disorder (OUD) treatment engagement have implications for population health. Continuum of care models can guide the opioid epidemic response by identifying differences in treatment patterns. We evaluated one such model at an integrated, safety-net health system in Denver, Colorado and examined the association of patient characteristics with opioid agonist treatment (OAT) receipt and retention. Methods: We identified a cohort of patients with OUD from 2023 to 2024 from electronic health records. We used multivariable regression to estimate the association of sociodemographic and health factors with OAT receipt and 90-day retention. Results: Of 8,954 patients with OUD, 40% received OAT and 40% of those were retained on OAT at 90 days. Non-Hispanic Black patients and those with co-occurring alcohol use disorder had a lower likelihood of OAT receipt (Risk Ratio [RR] vs non-Hispanic White 0.68, 95% CI: 0.62-0.76; RR vs no alcohol use disorder: 0.88, 95% CI: 0.83-0.32). Patients without insurance and young adults aged 18-24 years had a lower likelihood of OAT receipt and retention. Those with co-occurring mental health conditions had a higher likelihood of OAT receipt and retention. Co-occurring stimulant use disorder, age 55+, and medical comorbidities had differential associations between OAT receipt and retention. Conclusions: Associations between patient characteristics and OAT receipt and retention suggest three patterns: cumulative disadvantage with factors associated with both lower treatment and retention; uneven disadvantage for factors associated with either decreased treatment or retention; and inverse associations wherein factors showed benefit in one stage but disadvantage in the other. [ABSTRACT FROM AUTHOR]
Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Sociodemographic Factors Associated with Opioid Agonist Treatment Receipt and Retention at an Integrated Safety-Net Health System.
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  Data: <searchLink fieldCode="JN" term="%22Substance+Use+%26+Misuse%22">Substance Use & Misuse</searchLink>. 2026, Vol. 61 Issue 13, p2264-2272. 9p.
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  Data: Introduction: Sociodemographic differences in opioid use disorder (OUD) treatment engagement have implications for population health. Continuum of care models can guide the opioid epidemic response by identifying differences in treatment patterns. We evaluated one such model at an integrated, safety-net health system in Denver, Colorado and examined the association of patient characteristics with opioid agonist treatment (OAT) receipt and retention. Methods: We identified a cohort of patients with OUD from 2023 to 2024 from electronic health records. We used multivariable regression to estimate the association of sociodemographic and health factors with OAT receipt and 90-day retention. Results: Of 8,954 patients with OUD, 40% received OAT and 40% of those were retained on OAT at 90 days. Non-Hispanic Black patients and those with co-occurring alcohol use disorder had a lower likelihood of OAT receipt (Risk Ratio [RR] vs non-Hispanic White 0.68, 95% CI: 0.62-0.76; RR vs no alcohol use disorder: 0.88, 95% CI: 0.83-0.32). Patients without insurance and young adults aged 18-24 years had a lower likelihood of OAT receipt and retention. Those with co-occurring mental health conditions had a higher likelihood of OAT receipt and retention. Co-occurring stimulant use disorder, age 55+, and medical comorbidities had differential associations between OAT receipt and retention. Conclusions: Associations between patient characteristics and OAT receipt and retention suggest three patterns: cumulative disadvantage with factors associated with both lower treatment and retention; uneven disadvantage for factors associated with either decreased treatment or retention; and inverse associations wherein factors showed benefit in one stage but disadvantage in the other. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1080/10826084.2026.2651447
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      – Code: eng
        Text: English
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      – SubjectFull: Methadone treatment programs
        Type: general
      – SubjectFull: Clinical drug trials
        Type: general
      – SubjectFull: Substance abuse
        Type: general
      – SubjectFull: Patient compliance
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      – SubjectFull: Colorado
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      – TitleFull: Sociodemographic Factors Associated with Opioid Agonist Treatment Receipt and Retention at an Integrated Safety-Net Health System.
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