Early admission to stroke unit influences clinical outcome.

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Title: Early admission to stroke unit influences clinical outcome.
Authors: Silvestrelli, G., Parnetti, L., Paciaroni, M., Caso, V., Corea, F., Vitali, R., Capocchi, G., Agnelli, G.
Source: European Journal of Neurology. Mar2006, Vol. 13 Issue 3, p250-255. 6p. 5 Charts, 1 Graph.
Subjects: Cerebrovascular disease patients, Thrombolytic therapy, Endocarditis, Ventricular aneurysms, Hypokinesia, Etiology of diseases, Echocardiography, Myocardial infarction
Abstract: An improvement in patient arrival time to stroke unit (SU) is recommended, since earlier stroke management seems to improve ‘per se’ functional outcome. The objective of this study was to determine if early admission influences the outcome, reduces disability and mortality at discharge and three months later independent of tlirombolytic treatment. Consecutive acute stroke patients admitted to SU between January 1st 2000 and December 31st 2003 were studied in order to analyze the actual role of acute management independent specific pharmacological treatment, we excluded subjects who underwent rt-PA. 35.8% of 2,041 consecutive stroke patients arrived within 3 hours; 62.4% within 6 hours; 37.6% arrived later. Approximately 80% of the <6 hour patients presented a National Institutes of Health Stroke Scale (NIHSS) >4 and modified Rankin Scale (mRS) score >2 in comparison with 60% of the >6 hour patients. In hospital (8.7%) and three-month (7.3%) mortality in <3 hour patients were not significantly different from what observed in >3 hour patients (6.8% and 6.1% respectively) while functional outcome after three months was better in <3 hour patients (NIHSS: 34.6 vs 15.2; mRS: 32.9% vs 16.8%). Old age, history of TIA, cardioembolic etiology, severity of neurological deficit and hemorrhagic stroke type all led to earlier arrival time. Admission within 3 hours ‘per se’ improves outcome and reduced disability at three months. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Early admission to stroke unit influences clinical outcome.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Silvestrelli%2C+G%2E%22&quot;&gt;Silvestrelli, G.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Parnetti%2C+L%2E%22&quot;&gt;Parnetti, L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Paciaroni%2C+M%2E%22&quot;&gt;Paciaroni, M.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Caso%2C+V%2E%22&quot;&gt;Caso, V.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Corea%2C+F%2E%22&quot;&gt;Corea, F.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Vitali%2C+R%2E%22&quot;&gt;Vitali, R.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Capocchi%2C+G%2E%22&quot;&gt;Capocchi, G.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Agnelli%2C+G%2E%22&quot;&gt;Agnelli, G.&lt;/searchLink&gt;
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22European+Journal+of+Neurology%22&quot;&gt;European Journal of Neurology&lt;/searchLink&gt;. Mar2006, Vol. 13 Issue 3, p250-255. 6p. 5 Charts, 1 Graph.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cerebrovascular+disease+patients%22&quot;&gt;Cerebrovascular disease patients&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Thrombolytic+therapy%22&quot;&gt;Thrombolytic therapy&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Endocarditis%22&quot;&gt;Endocarditis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Ventricular+aneurysms%22&quot;&gt;Ventricular aneurysms&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Hypokinesia%22&quot;&gt;Hypokinesia&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Etiology+of+diseases%22&quot;&gt;Etiology of diseases&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Echocardiography%22&quot;&gt;Echocardiography&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Myocardial+infarction%22&quot;&gt;Myocardial infarction&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: An improvement in patient arrival time to stroke unit (SU) is recommended, since earlier stroke management seems to improve ‘per se’ functional outcome. The objective of this study was to determine if early admission influences the outcome, reduces disability and mortality at discharge and three months later independent of tlirombolytic treatment. Consecutive acute stroke patients admitted to SU between January 1st 2000 and December 31st 2003 were studied in order to analyze the actual role of acute management independent specific pharmacological treatment, we excluded subjects who underwent rt-PA. 35.8% of 2,041 consecutive stroke patients arrived within 3 hours; 62.4% within 6 hours; 37.6% arrived later. Approximately 80% of the &lt;6 hour patients presented a National Institutes of Health Stroke Scale (NIHSS) &gt;4 and modified Rankin Scale (mRS) score &gt;2 in comparison with 60% of the &gt;6 hour patients. In hospital (8.7%) and three-month (7.3%) mortality in &lt;3 hour patients were not significantly different from what observed in &gt;3 hour patients (6.8% and 6.1% respectively) while functional outcome after three months was better in &lt;3 hour patients (NIHSS: 34.6 vs 15.2; mRS: 32.9% vs 16.8%). Old age, history of TIA, cardioembolic etiology, severity of neurological deficit and hemorrhagic stroke type all led to earlier arrival time. Admission within 3 hours ‘per se’ improves outcome and reduced disability at three months. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1111/j.1468-1331.2006.01187.x
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 6
        StartPage: 250
    Subjects:
      – SubjectFull: Cerebrovascular disease patients
        Type: general
      – SubjectFull: Thrombolytic therapy
        Type: general
      – SubjectFull: Endocarditis
        Type: general
      – SubjectFull: Ventricular aneurysms
        Type: general
      – SubjectFull: Hypokinesia
        Type: general
      – SubjectFull: Etiology of diseases
        Type: general
      – SubjectFull: Echocardiography
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      – SubjectFull: Myocardial infarction
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      – TitleFull: Early admission to stroke unit influences clinical outcome.
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            NameFull: Silvestrelli, G.
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            NameFull: Parnetti, L.
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            NameFull: Paciaroni, M.
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            NameFull: Caso, V.
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            NameFull: Corea, F.
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            NameFull: Capocchi, G.
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              Text: Mar2006
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