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The Relation of White Matter Hyperintensities to Cognitive Performance in the Normal Old: Education Matters.

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Title: The Relation of White Matter Hyperintensities to Cognitive Performance in the Normal Old: Education Matters.
Authors: Nebes, Robert, Meltzer, Carolyn, Whyte, Ellen, Scanlon, Joelle, Halligan, Edythe, Saxton, Judith, Houck, Patricia, Boada, Fernando, DeKosky, Steven
Source: Aging, Neuropsychology & Cognition. Sep2006, Vol. 13 Issue 3/4, p326-340. 14p. 3 Charts.
Subjects: Aging, Cognitive ability, Short-term memory, Response inhibition, Neurological disorders, Older people
Abstract: This study examined whether the severity of cerebral white matter abnormalities (evident on MR images as white matter hyperintensities (WMH)) was related to the cognitive performance of 141 high-functioning older adults. The elderly showed the typical age decrement on measures of processing speed, working memory, and inhibition; however WMH severity was significantly related only to processing speed. The strength of this relationship was, however, influenced by the educational level of the participants, such that processing speed was more associated with WMH severity in less-educated than in well-educated participants. This is consistent with recent concepts of cognitive reserve, but does raise a question as to the underlying source of the cognitive decrement found in the sort of well-educated elders typically used in cognitive-aging studies. [ABSTRACT FROM AUTHOR]
Copyright of Aging, Neuropsychology & Cognition is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: The Relation of White Matter Hyperintensities to Cognitive Performance in the Normal Old: Education Matters.
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  Data: <searchLink fieldCode="AR" term="%22Nebes%2C+Robert%22">Nebes, Robert</searchLink><br /><searchLink fieldCode="AR" term="%22Meltzer%2C+Carolyn%22">Meltzer, Carolyn</searchLink><br /><searchLink fieldCode="AR" term="%22Whyte%2C+Ellen%22">Whyte, Ellen</searchLink><br /><searchLink fieldCode="AR" term="%22Scanlon%2C+Joelle%22">Scanlon, Joelle</searchLink><br /><searchLink fieldCode="AR" term="%22Halligan%2C+Edythe%22">Halligan, Edythe</searchLink><br /><searchLink fieldCode="AR" term="%22Saxton%2C+Judith%22">Saxton, Judith</searchLink><br /><searchLink fieldCode="AR" term="%22Houck%2C+Patricia%22">Houck, Patricia</searchLink><br /><searchLink fieldCode="AR" term="%22Boada%2C+Fernando%22">Boada, Fernando</searchLink><br /><searchLink fieldCode="AR" term="%22DeKosky%2C+Steven%22">DeKosky, Steven</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Aging%2C+Neuropsychology+%26+Cognition%22">Aging, Neuropsychology & Cognition</searchLink>. Sep2006, Vol. 13 Issue 3/4, p326-340. 14p. 3 Charts.
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  Data: <searchLink fieldCode="DE" term="%22Aging%22">Aging</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+ability%22">Cognitive ability</searchLink><br /><searchLink fieldCode="DE" term="%22Short-term+memory%22">Short-term memory</searchLink><br /><searchLink fieldCode="DE" term="%22Response+inhibition%22">Response inhibition</searchLink><br /><searchLink fieldCode="DE" term="%22Neurological+disorders%22">Neurological disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Older+people%22">Older people</searchLink>
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  Data: This study examined whether the severity of cerebral white matter abnormalities (evident on MR images as white matter hyperintensities (WMH)) was related to the cognitive performance of 141 high-functioning older adults. The elderly showed the typical age decrement on measures of processing speed, working memory, and inhibition; however WMH severity was significantly related only to processing speed. The strength of this relationship was, however, influenced by the educational level of the participants, such that processing speed was more associated with WMH severity in less-educated than in well-educated participants. This is consistent with recent concepts of cognitive reserve, but does raise a question as to the underlying source of the cognitive decrement found in the sort of well-educated elders typically used in cognitive-aging studies. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Aging, Neuropsychology & Cognition is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: Sep2006
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