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Correlation of liver dysfunction biological markers to the mood status of alcohol-dependent individuals.

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Title: Correlation of liver dysfunction biological markers to the mood status of alcohol-dependent individuals.
Authors: Liappas, Ioannis A. (AUTHOR), Piperi, Christina (AUTHOR), Malitas, Petros N. (AUTHOR), Tzavellas, Elias O. (AUTHOR), Liappas, Alexandros I. (AUTHOR), Boufidou, Fotini (AUTHOR), Kalofoutis, Christos A. (AUTHOR), Bagos, Pandelis (AUTHOR), Rabavilas, Andreas (AUTHOR), Kalofoutis, Anastasios (AUTHOR)
Source: International Journal of Psychiatry in Clinical Practice. Sep2006, Vol. 10 Issue 3, p166-173. 8p. 3 Charts.
Subjects: Affective disorders, Alcohol drinking, Alcoholism, Liver failure, Detoxification (Alternative medicine), Anxiety
Abstract: Objective: Alcohol intake is a major cause of liver cirrhosis as well as chronic liver disease, and commonly coexists with mood disorders such as depression and anxiety. The aim of the present study was to investigate the possible correlation between liver dysfunction related to alcohol intake with anxiety and depressive-like symptomatology prior to and after the detoxification period. Methods: One hundred alcohol abusing/dependent subjects (81 males and 19 females) were treated on an inpatient basis according to a standard detoxification protocol and measurements of serum levels of hepatic enzymes (ASAT, ALAT, γGT), and measures of anxiety (HARS), depression (HDRS) and global functioning (GAS) were also obtained at baseline and at weekly intervals over a period of 4 weeks. Results: Increased levels of hepatic enzymes were observed upon admission that were significantly reduced ( P [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Psychiatry in Clinical Practice is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Correlation of liver dysfunction biological markers to the mood status of alcohol-dependent individuals.
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  Data: <searchLink fieldCode="AR" term="%22Liappas%2C+Ioannis+A%2E%22">Liappas, Ioannis A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Piperi%2C+Christina%22">Piperi, Christina</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Malitas%2C+Petros+N%2E%22">Malitas, Petros N.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tzavellas%2C+Elias+O%2E%22">Tzavellas, Elias O.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liappas%2C+Alexandros+I%2E%22">Liappas, Alexandros I.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Boufidou%2C+Fotini%22">Boufidou, Fotini</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kalofoutis%2C+Christos+A%2E%22">Kalofoutis, Christos A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bagos%2C+Pandelis%22">Bagos, Pandelis</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rabavilas%2C+Andreas%22">Rabavilas, Andreas</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kalofoutis%2C+Anastasios%22">Kalofoutis, Anastasios</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Psychiatry+in+Clinical+Practice%22">International Journal of Psychiatry in Clinical Practice</searchLink>. Sep2006, Vol. 10 Issue 3, p166-173. 8p. 3 Charts.
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  Data: <searchLink fieldCode="DE" term="%22Affective+disorders%22">Affective disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Alcohol+drinking%22">Alcohol drinking</searchLink><br /><searchLink fieldCode="DE" term="%22Alcoholism%22">Alcoholism</searchLink><br /><searchLink fieldCode="DE" term="%22Liver+failure%22">Liver failure</searchLink><br /><searchLink fieldCode="DE" term="%22Detoxification+%28Alternative+medicine%29%22">Detoxification (Alternative medicine)</searchLink><br /><searchLink fieldCode="DE" term="%22Anxiety%22">Anxiety</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Objective: Alcohol intake is a major cause of liver cirrhosis as well as chronic liver disease, and commonly coexists with mood disorders such as depression and anxiety. The aim of the present study was to investigate the possible correlation between liver dysfunction related to alcohol intake with anxiety and depressive-like symptomatology prior to and after the detoxification period. Methods: One hundred alcohol abusing/dependent subjects (81 males and 19 females) were treated on an inpatient basis according to a standard detoxification protocol and measurements of serum levels of hepatic enzymes (ASAT, ALAT, γGT), and measures of anxiety (HARS), depression (HDRS) and global functioning (GAS) were also obtained at baseline and at weekly intervals over a period of 4 weeks. Results: Increased levels of hepatic enzymes were observed upon admission that were significantly reduced ( P [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Group: Ab
  Data: <i>Copyright of International Journal of Psychiatry in Clinical Practice is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=22138891
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        Value: 10.1080/13651500600633287
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      – SubjectFull: Anxiety
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      – TitleFull: Correlation of liver dysfunction biological markers to the mood status of alcohol-dependent individuals.
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              M: 09
              Text: Sep2006
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