The persistence of depression score.

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Title: The persistence of depression score.
Authors: Spijker, J. (AUTHOR), De Graaf, R. (AUTHOR), Ormel, J. (AUTHOR), Nolen, W. A. (AUTHOR), Grobbee, D. E. (AUTHOR), Burger, H. (AUTHOR)
Source: Acta Psychiatrica Scandinavica. Dec2006, Vol. 114 Issue 6, p411-416. 6p. 4 Charts, 1 Graph.
Subjects: Mental depression, Age groups, Prognosis, Health risk assessment, Social support
Abstract: Objective: To construct a score that allows prediction of major depressive episode (MDE) persistence in individuals with MDE using determinants of persistence identified in previous research. Method: Data were derived from 250 subjects from the general population with new MDE according to DSM-III-R. These subjects were recruited from the Netherlands Mental Health Survey and Incidence Study (NEMESIS), using the Composite International Diagnostic Interview. Determinants for persistence were transformed into a practical risk score using proportional hazards models and bootstrapping techniques. Results: The risk of MDE persistence after 12 months was 23%. The score comprised measures of physical illness, social support, depression severity and recurrency, and duration of previous episodes. With increasing categories of these measures, the predicted risks increased from 7 to 40%. Conclusion: We constructed the Persistence of Depression Score (PDS) showing reasonable performance. The PDS could be of importance in clinical practice to support treatment decisions. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
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Abstract:Objective: To construct a score that allows prediction of major depressive episode (MDE) persistence in individuals with MDE using determinants of persistence identified in previous research. Method: Data were derived from 250 subjects from the general population with new MDE according to DSM-III-R. These subjects were recruited from the Netherlands Mental Health Survey and Incidence Study (NEMESIS), using the Composite International Diagnostic Interview. Determinants for persistence were transformed into a practical risk score using proportional hazards models and bootstrapping techniques. Results: The risk of MDE persistence after 12 months was 23%. The score comprised measures of physical illness, social support, depression severity and recurrency, and duration of previous episodes. With increasing categories of these measures, the predicted risks increased from 7 to 40%. Conclusion: We constructed the Persistence of Depression Score (PDS) showing reasonable performance. The PDS could be of importance in clinical practice to support treatment decisions. [ABSTRACT FROM AUTHOR]
ISSN:0001690X
DOI:10.1111/j.1600-0447.2006.00821.x