Peripheral large nerve fibre function in patients with chronic plaque psoriasis.

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Title: Peripheral large nerve fibre function in patients with chronic plaque psoriasis.
Authors: Chroni, E., Georgiou, S., Polychronopoulos, P., Sagriotis, A., Monastirli, A., Pasmatzi, E., Tsambaos, D.
Source: European Journal of Neurology. Jan2007, Vol. 14 Issue 1, p18-20. 3p. 1 Chart.
Subjects: Psoriasis, Peripheral neuropathy, Neurologic examination, Neural conduction, Neuropathy, Neurophysiology, Patients
Abstract: Accumulating evidence suggests the involvement of neurogenic inflammation in the pathogenesis of psoriasis. Moreover, the concomitant occurrence of peripheral neuropathy has been reported in several psoriatic patients. Thus, the aim of the present study was to answer the question whether an impairment of peripheral large nerve fibre function may exist in psoriasis. Thirty-two patients with severe and generalized chronic plaque psoriasis and 32 sex- and age-matched healthy controls were evaluated by detailed clinical neurological and standard neurophysiological examination. The latter included motor nerve conduction study of one nerve in the upper and one in the lower extremities and sensory nerve conduction study of one nerve in the upper and two in the lower extremities. Neurological examination failed to demonstrate any clinical evidence of large fibre neuropathy. Furthermore, all values of the examined neurophysiological parameters were within normal limits; comparisons of the corresponding mean values in the patient and the control group showed no statistically significant differences. These findings demonstrate no measurable abnormalities of the peripheral large nerve fibres in psoriatic patients and therefore an association of psoriasis with peripheral large fibre neuropathy cannot be suggested. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Peripheral large nerve fibre function in patients with chronic plaque psoriasis.
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  Data: <searchLink fieldCode="AR" term="%22Chroni%2C+E%2E%22">Chroni, E.</searchLink><br /><searchLink fieldCode="AR" term="%22Georgiou%2C+S%2E%22">Georgiou, S.</searchLink><br /><searchLink fieldCode="AR" term="%22Polychronopoulos%2C+P%2E%22">Polychronopoulos, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Sagriotis%2C+A%2E%22">Sagriotis, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Monastirli%2C+A%2E%22">Monastirli, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Pasmatzi%2C+E%2E%22">Pasmatzi, E.</searchLink><br /><searchLink fieldCode="AR" term="%22Tsambaos%2C+D%2E%22">Tsambaos, D.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neurology%22">European Journal of Neurology</searchLink>. Jan2007, Vol. 14 Issue 1, p18-20. 3p. 1 Chart.
– Name: Subject
  Label: Subjects
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  Data: <searchLink fieldCode="DE" term="%22Psoriasis%22">Psoriasis</searchLink><br /><searchLink fieldCode="DE" term="%22Peripheral+neuropathy%22">Peripheral neuropathy</searchLink><br /><searchLink fieldCode="DE" term="%22Neurologic+examination%22">Neurologic examination</searchLink><br /><searchLink fieldCode="DE" term="%22Neural+conduction%22">Neural conduction</searchLink><br /><searchLink fieldCode="DE" term="%22Neuropathy%22">Neuropathy</searchLink><br /><searchLink fieldCode="DE" term="%22Neurophysiology%22">Neurophysiology</searchLink><br /><searchLink fieldCode="DE" term="%22Patients%22">Patients</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Accumulating evidence suggests the involvement of neurogenic inflammation in the pathogenesis of psoriasis. Moreover, the concomitant occurrence of peripheral neuropathy has been reported in several psoriatic patients. Thus, the aim of the present study was to answer the question whether an impairment of peripheral large nerve fibre function may exist in psoriasis. Thirty-two patients with severe and generalized chronic plaque psoriasis and 32 sex- and age-matched healthy controls were evaluated by detailed clinical neurological and standard neurophysiological examination. The latter included motor nerve conduction study of one nerve in the upper and one in the lower extremities and sensory nerve conduction study of one nerve in the upper and two in the lower extremities. Neurological examination failed to demonstrate any clinical evidence of large fibre neuropathy. Furthermore, all values of the examined neurophysiological parameters were within normal limits; comparisons of the corresponding mean values in the patient and the control group showed no statistically significant differences. These findings demonstrate no measurable abnormalities of the peripheral large nerve fibres in psoriatic patients and therefore an association of psoriasis with peripheral large fibre neuropathy cannot be suggested. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1111/j.1468-1331.2006.01522.x
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      – Code: eng
        Text: English
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        PageCount: 3
        StartPage: 18
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      – SubjectFull: Psoriasis
        Type: general
      – SubjectFull: Peripheral neuropathy
        Type: general
      – SubjectFull: Neurologic examination
        Type: general
      – SubjectFull: Neural conduction
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      – SubjectFull: Neuropathy
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      – SubjectFull: Neurophysiology
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      – SubjectFull: Patients
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      – TitleFull: Peripheral large nerve fibre function in patients with chronic plaque psoriasis.
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            NameFull: Chroni, E.
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            NameFull: Georgiou, S.
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            NameFull: Sagriotis, A.
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            NameFull: Monastirli, A.
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            NameFull: Pasmatzi, E.
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              Text: Jan2007
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              Y: 2007
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