Post-mortem proton magnetic resonance spectrometric measures of brain regions in patients with a pathological diagnosis of Alzheimer's disease and multi-infarct dementia.
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| Title: | Post-mortem proton magnetic resonance spectrometric measures of brain regions in patients with a pathological diagnosis of Alzheimer's disease and multi-infarct dementia. |
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| Authors: | Besson, John A.O., Best, Philip V., Skinner, E. Roy, Besson, J A (AUTHOR), Best, P V (AUTHOR), Skinner, E R (AUTHOR) |
| Source: | British Journal of Psychiatry. Feb92, Vol. 160, p187-190. 4p. 2 Charts. |
| Subjects: | Magnetic resonance imaging, Spectrum analysis, Alzheimer's disease, Dementia, Diagnosis, Brain, Comparative studies, Research methodology, Medical cooperation, Nuclear magnetic resonance spectroscopy, Research, Evaluation research, In vitro studies, Multi-infarct dementia |
| Abstract: | In-vitro spectrometric measures were made of spin-lattice (T1) and spin-spin (T2) relaxation times of samples of grey and white matter from the brains of 15 patients with a pathological diagnosis of Alzheimer's disease, 5 with multi-infarct dementia, and 11 non-demented subjects. Relaxation times were significantly greater in the parietal white matter and temporal white matter of patients with Alzheimer's disease compared with that of the other subjects. This was associated with an increase in tissue water content. These findings confirm measures obtained in some imaging studies. [ABSTRACT FROM AUTHOR] |
| Copyright of British Journal of Psychiatry is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 24871021 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Post-mortem proton magnetic resonance spectrometric measures of brain regions in patients with a pathological diagnosis of Alzheimer's disease and multi-infarct dementia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Besson%2C+John+A%2EO%2E%22">Besson, John A.O.</searchLink><br /><searchLink fieldCode="AR" term="%22Best%2C+Philip+V%2E%22">Best, Philip V.</searchLink><br /><searchLink fieldCode="AR" term="%22Skinner%2C+E%2E+Roy%22">Skinner, E. Roy</searchLink><br /><searchLink fieldCode="AR" term="%22Besson%2C+J+A%22">Besson, J A</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Best%2C+P+V%22">Best, P V</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Skinner%2C+E+R%22">Skinner, E R</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22British+Journal+of+Psychiatry%22">British Journal of Psychiatry</searchLink>. Feb92, Vol. 160, p187-190. 4p. 2 Charts. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Spectrum+analysis%22">Spectrum analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Alzheimer's+disease%22">Alzheimer's disease</searchLink><br /><searchLink fieldCode="DE" term="%22Dementia%22">Dementia</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnosis%22">Diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Brain%22">Brain</searchLink><br /><searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br /><searchLink fieldCode="DE" term="%22Research+methodology%22">Research methodology</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+cooperation%22">Medical cooperation</searchLink><br /><searchLink fieldCode="DE" term="%22Nuclear+magnetic+resonance+spectroscopy%22">Nuclear magnetic resonance spectroscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Research%22">Research</searchLink><br /><searchLink fieldCode="DE" term="%22Evaluation+research%22">Evaluation research</searchLink><br /><searchLink fieldCode="DE" term="%22In+vitro+studies%22">In vitro studies</searchLink><br /><searchLink fieldCode="DE" term="%22Multi-infarct+dementia%22">Multi-infarct dementia</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: In-vitro spectrometric measures were made of spin-lattice (T1) and spin-spin (T2) relaxation times of samples of grey and white matter from the brains of 15 patients with a pathological diagnosis of Alzheimer's disease, 5 with multi-infarct dementia, and 11 non-demented subjects. Relaxation times were significantly greater in the parietal white matter and temporal white matter of patients with Alzheimer's disease compared with that of the other subjects. This was associated with an increase in tissue water content. These findings confirm measures obtained in some imaging studies. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of British Journal of Psychiatry is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1192/bjp.160.2.187 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 4 StartPage: 187 Subjects: – SubjectFull: Magnetic resonance imaging Type: general – SubjectFull: Spectrum analysis Type: general – SubjectFull: Alzheimer's disease Type: general – SubjectFull: Dementia Type: general – SubjectFull: Diagnosis Type: general – SubjectFull: Brain Type: general – SubjectFull: Comparative studies Type: general – SubjectFull: Research methodology Type: general – SubjectFull: Medical cooperation Type: general – SubjectFull: Nuclear magnetic resonance spectroscopy Type: general – SubjectFull: Research Type: general – SubjectFull: Evaluation research Type: general – SubjectFull: In vitro studies Type: general – SubjectFull: Multi-infarct dementia Type: general Titles: – TitleFull: Post-mortem proton magnetic resonance spectrometric measures of brain regions in patients with a pathological diagnosis of Alzheimer's disease and multi-infarct dementia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Besson, John A.O. – PersonEntity: Name: NameFull: Best, Philip V. – PersonEntity: Name: NameFull: Skinner, E. Roy – PersonEntity: Name: NameFull: Besson, J A – PersonEntity: Name: NameFull: Best, P V – PersonEntity: Name: NameFull: Skinner, E R IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: Feb92 Type: published Y: 1992 Identifiers: – Type: issn-print Value: 00071250 Numbering: – Type: volume Value: 160 Titles: – TitleFull: British Journal of Psychiatry Type: main |
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