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Lower Extremity Motor Function and Disability in Mild Cognitive Impairment.

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Title: Lower Extremity Motor Function and Disability in Mild Cognitive Impairment.
Authors: Boyle, P. A. (AUTHOR), Wilson, R. S. (AUTHOR), Buchman, A. S. (AUTHOR), Aggarwal, N. T. (AUTHOR), Tang, Y. (AUTHOR), Arvanitakis, Z. (AUTHOR), Kelly, J. (AUTHOR), Bennett, D. A. (AUTHOR)
Source: Experimental Aging Research. Jul-Sep2007, Vol. 33 Issue 3, p355-371. 17p. 2 Charts, 2 Graphs.
Subjects: Leg, Cognition disorders, Diseases in older people, Movement disorders, Memory, Age groups
Abstract: Recent findings suggest that lower extremity motor dysfunction may be a feature of mild cognitive impairment (MCI), but little is known about the nature and significance of lower extremity motor dysfunction in MCI. The aim of this study was to examine the extent to which MCI is associated with impaired gait, balance, and strength and to examine the relation of lower extremity function to disability among persons with MCI in the Rush Memory and Aging Project, a clinical-pathologic study of common chronic conditions of old age. In a series of analyses adjusted for age, sex, and education, individuals with MCI exhibited more impaired gait and balance than individuals without cognitive impairment. Because vascular factors can contribute to lower extremity motor dysfunction, the authors repeated the initial analyses including terms for vascular risk factors and vascular disease, and the associations between MCI and lower extremity motor dysfunction persisted. Moreover, among those with MCI, impairments in gait and balance were associated with an increased likelihood of disability. These findings suggest that lower extremity motor dysfunction is common and contributes to disability in MCI, but lower extremity motor dysfunction in MCI does not appear to be explained by the vascular factors examined in this study. [ABSTRACT FROM AUTHOR]
Copyright of Experimental Aging Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Lower Extremity Motor Function and Disability in Mild Cognitive Impairment.
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  Data: <searchLink fieldCode="AR" term="%22Boyle%2C+P%2E+A%2E%22">Boyle, P. A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wilson%2C+R%2E+S%2E%22">Wilson, R. S.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Buchman%2C+A%2E+S%2E%22">Buchman, A. S.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Aggarwal%2C+N%2E+T%2E%22">Aggarwal, N. T.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tang%2C+Y%2E%22">Tang, Y.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Arvanitakis%2C+Z%2E%22">Arvanitakis, Z.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kelly%2C+J%2E%22">Kelly, J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bennett%2C+D%2E+A%2E%22">Bennett, D. A.</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Experimental+Aging+Research%22">Experimental Aging Research</searchLink>. Jul-Sep2007, Vol. 33 Issue 3, p355-371. 17p. 2 Charts, 2 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Leg%22">Leg</searchLink><br /><searchLink fieldCode="DE" term="%22Cognition+disorders%22">Cognition disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Diseases+in+older+people%22">Diseases in older people</searchLink><br /><searchLink fieldCode="DE" term="%22Movement+disorders%22">Movement disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Memory%22">Memory</searchLink><br /><searchLink fieldCode="DE" term="%22Age+groups%22">Age groups</searchLink>
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  Data: Recent findings suggest that lower extremity motor dysfunction may be a feature of mild cognitive impairment (MCI), but little is known about the nature and significance of lower extremity motor dysfunction in MCI. The aim of this study was to examine the extent to which MCI is associated with impaired gait, balance, and strength and to examine the relation of lower extremity function to disability among persons with MCI in the Rush Memory and Aging Project, a clinical-pathologic study of common chronic conditions of old age. In a series of analyses adjusted for age, sex, and education, individuals with MCI exhibited more impaired gait and balance than individuals without cognitive impairment. Because vascular factors can contribute to lower extremity motor dysfunction, the authors repeated the initial analyses including terms for vascular risk factors and vascular disease, and the associations between MCI and lower extremity motor dysfunction persisted. Moreover, among those with MCI, impairments in gait and balance were associated with an increased likelihood of disability. These findings suggest that lower extremity motor dysfunction is common and contributes to disability in MCI, but lower extremity motor dysfunction in MCI does not appear to be explained by the vascular factors examined in this study. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Experimental Aging Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – SubjectFull: Leg
        Type: general
      – SubjectFull: Cognition disorders
        Type: general
      – SubjectFull: Diseases in older people
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      – SubjectFull: Movement disorders
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      – SubjectFull: Memory
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      – SubjectFull: Age groups
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      – TitleFull: Lower Extremity Motor Function and Disability in Mild Cognitive Impairment.
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              Text: Jul-Sep2007
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              Y: 2007
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