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Effect of celecoxib on restenosis after coronary angioplasty with a Taxus stent (COREA-TAXUS trial): an open-label randomised controlled study.

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Title: Effect of celecoxib on restenosis after coronary angioplasty with a Taxus stent (COREA-TAXUS trial): an open-label randomised controlled study.
Authors: Koo, Bon-Kwon, Kim, Yong-Seok, Park, Kyung-Woo, Yang, Han-Mo, Kwon, Dang-A, Chung, Jin-Wook, Hahn, Joo-Yong, Lee, Hae-Young, Park, Jin-Shik, Kang, Hyun-Jae, Cho, Yound-Seok, Youn, Tae-Jin, Chung, Woo-Young, Chae, In-Ho, Choi, Dong-Ju, Oh, Byung-Hee, Park, Young-Bae, Kim, Hyo-Soo
Source: Lancet. 8/18/2007, Vol. 370 Issue 9587, p567-574. 8p.
Subjects: Clinical trials, Celecoxib, Surgical stents, Myocardial infarction treatment, Paclitaxel, Medical research, Medical experimentation on humans, Coronary artery surgery, Therapeutics
Abstract: The article presents the results of a two-center clinical trial to determine whether taking the drug celecoxib can retard or prevent restenosis in patients who where implanted with paclitaxel-eluting stents during coronary angioplasty surgery. All patients received aspirin and clopidogrel daily, while half also received 400mg of celecoxib daily. After six months, stent luminal loss was lower in the group receiving celecoxib, with a lower incidence of secondary events including cardiac death or myocardial infarction due to a reduced need for revascularization of the target lesion. The authors conclude celecoxib is a safe treatment after stent implantation in patients with coronary artery disease that can reduce the need for revascularization of the target lesion.
Database: Psychology and Behavioral Sciences Collection
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  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 26295365
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Label: Title
  Group: Ti
  Data: Effect of celecoxib on restenosis after coronary angioplasty with a Taxus stent (COREA-TAXUS trial): an open-label randomised controlled study.
– Name: Author
  Label: Authors
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  Data: <searchLink fieldCode="AR" term="%22Koo%2C+Bon-Kwon%22">Koo, Bon-Kwon</searchLink><br /><searchLink fieldCode="AR" term="%22Kim%2C+Yong-Seok%22">Kim, Yong-Seok</searchLink><br /><searchLink fieldCode="AR" term="%22Park%2C+Kyung-Woo%22">Park, Kyung-Woo</searchLink><br /><searchLink fieldCode="AR" term="%22Yang%2C+Han-Mo%22">Yang, Han-Mo</searchLink><br /><searchLink fieldCode="AR" term="%22Kwon%2C+Dang-A%22">Kwon, Dang-A</searchLink><br /><searchLink fieldCode="AR" term="%22Chung%2C+Jin-Wook%22">Chung, Jin-Wook</searchLink><br /><searchLink fieldCode="AR" term="%22Hahn%2C+Joo-Yong%22">Hahn, Joo-Yong</searchLink><br /><searchLink fieldCode="AR" term="%22Lee%2C+Hae-Young%22">Lee, Hae-Young</searchLink><br /><searchLink fieldCode="AR" term="%22Park%2C+Jin-Shik%22">Park, Jin-Shik</searchLink><br /><searchLink fieldCode="AR" term="%22Kang%2C+Hyun-Jae%22">Kang, Hyun-Jae</searchLink><br /><searchLink fieldCode="AR" term="%22Cho%2C+Yound-Seok%22">Cho, Yound-Seok</searchLink><br /><searchLink fieldCode="AR" term="%22Youn%2C+Tae-Jin%22">Youn, Tae-Jin</searchLink><br /><searchLink fieldCode="AR" term="%22Chung%2C+Woo-Young%22">Chung, Woo-Young</searchLink><br /><searchLink fieldCode="AR" term="%22Chae%2C+In-Ho%22">Chae, In-Ho</searchLink><br /><searchLink fieldCode="AR" term="%22Choi%2C+Dong-Ju%22">Choi, Dong-Ju</searchLink><br /><searchLink fieldCode="AR" term="%22Oh%2C+Byung-Hee%22">Oh, Byung-Hee</searchLink><br /><searchLink fieldCode="AR" term="%22Park%2C+Young-Bae%22">Park, Young-Bae</searchLink><br /><searchLink fieldCode="AR" term="%22Kim%2C+Hyo-Soo%22">Kim, Hyo-Soo</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 8/18/2007, Vol. 370 Issue 9587, p567-574. 8p.
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  Data: <searchLink fieldCode="DE" term="%22Clinical+trials%22">Clinical trials</searchLink><br /><searchLink fieldCode="DE" term="%22Celecoxib%22">Celecoxib</searchLink><br /><searchLink fieldCode="DE" term="%22Surgical+stents%22">Surgical stents</searchLink><br /><searchLink fieldCode="DE" term="%22Myocardial+infarction+treatment%22">Myocardial infarction treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Paclitaxel%22">Paclitaxel</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+research%22">Medical research</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+experimentation+on+humans%22">Medical experimentation on humans</searchLink><br /><searchLink fieldCode="DE" term="%22Coronary+artery+surgery%22">Coronary artery surgery</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The article presents the results of a two-center clinical trial to determine whether taking the drug celecoxib can retard or prevent restenosis in patients who where implanted with paclitaxel-eluting stents during coronary angioplasty surgery. All patients received aspirin and clopidogrel daily, while half also received 400mg of celecoxib daily. After six months, stent luminal loss was lower in the group receiving celecoxib, with a lower incidence of secondary events including cardiac death or myocardial infarction due to a reduced need for revascularization of the target lesion. The authors conclude celecoxib is a safe treatment after stent implantation in patients with coronary artery disease that can reduce the need for revascularization of the target lesion.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=26295365
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/S0140-6736(07)61295-1
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      – Code: eng
        Text: English
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        PageCount: 8
        StartPage: 567
    Subjects:
      – SubjectFull: Clinical trials
        Type: general
      – SubjectFull: Celecoxib
        Type: general
      – SubjectFull: Surgical stents
        Type: general
      – SubjectFull: Myocardial infarction treatment
        Type: general
      – SubjectFull: Paclitaxel
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      – SubjectFull: Medical research
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      – SubjectFull: Medical experimentation on humans
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      – SubjectFull: Coronary artery surgery
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      – SubjectFull: Therapeutics
        Type: general
    Titles:
      – TitleFull: Effect of celecoxib on restenosis after coronary angioplasty with a Taxus stent (COREA-TAXUS trial): an open-label randomised controlled study.
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              Text: 8/18/2007
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