Regional cerebral blood flow after recovery from anorexia or bulimia nervosa.

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Bibliographic Details
Title: Regional cerebral blood flow after recovery from anorexia or bulimia nervosa.
Authors: Frank, Guido K., Bailer, Ursula F., Meltzer, Carolyn C., Price, Julie C., Mathis, Chester A., Wagner, Angela, Becker, Carl, Kaye, Walter H.
Source: International Journal of Eating Disorders. Sep2007, Vol. 40 Issue 6, p488-492. 5p. 1 Chart, 1 Graph.
Subjects: Regional blood flow, Blood flow, Blood circulation, Anorexia nervosa, Bulimia, Medical radiography
Abstract: Objective: Abnormalities of regional cerebral blood flow (rCBF) have been found in individuals who are ill with anorexia (AN) or bulimia nervosa (BN). Little is known about whether rCBF normalizes after recovery from AN and BN. Method: Eighteen control women (CW), 10 recovered restricting type AN, 8 recovered AN with a binging history, and 9 recovered BN participants without a history of AN were studied using positron emission tomography and [15O]water in order to assess rCBF. Results: Partial volume corrected rCBF values in cortical and subcortical brain regions were similar between groups. Neither current body mass index nor age correlated with rCBF values. Conclusion: The results from this study indicate that rCBF normalizes with long-term recovery. Thus, altered rCBF is unlikely to confound functional imaging studies in AN or BN after recovery. © 2007 by Wiley Periodicals, Inc. Int J Eat Disord 2007. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
Description
Abstract:Objective: Abnormalities of regional cerebral blood flow (rCBF) have been found in individuals who are ill with anorexia (AN) or bulimia nervosa (BN). Little is known about whether rCBF normalizes after recovery from AN and BN. Method: Eighteen control women (CW), 10 recovered restricting type AN, 8 recovered AN with a binging history, and 9 recovered BN participants without a history of AN were studied using positron emission tomography and [15O]water in order to assess rCBF. Results: Partial volume corrected rCBF values in cortical and subcortical brain regions were similar between groups. Neither current body mass index nor age correlated with rCBF values. Conclusion: The results from this study indicate that rCBF normalizes with long-term recovery. Thus, altered rCBF is unlikely to confound functional imaging studies in AN or BN after recovery. © 2007 by Wiley Periodicals, Inc. Int J Eat Disord 2007. [ABSTRACT FROM AUTHOR]
ISSN:02763478
DOI:10.1002/eat.20395