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Sexual dysfunction in HIV-positive men is multi-factorial: A study of prevalence and associated factors.

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Title: Sexual dysfunction in HIV-positive men is multi-factorial: A study of prevalence and associated factors.
Authors: Asboe, D. (AUTHOR), Catalan, J. (AUTHOR), Mandalia, S. (AUTHOR), Dedes, N. (AUTHOR), Florence, E. (AUTHOR), Schrooten, W. (AUTHOR), Noestlinger, C. (AUTHOR), Colebunders, R. (AUTHOR)
Source: AIDS Care. Sep2007, Vol. 19 Issue 8, p955-965. 11p. 1 Chart, 2 Graphs.
Subjects: HIV-positive men, Sexual dysfunction, HIV-positive persons, Factor analysis, Disease prevalence, Epidemiology, Therapeutics, HIV infections, AIDS prevention
Geographic Terms: Europe
Abstract: To establish the prevalence of sexual dysfunction amongst HIV-positive men and to determine the factors associated with dysfunction we conducted a cross-sectional study in seven European HIV treatment centres. Data on medical history, antiretroviral treatment and laboratory results were collected by interview and case record review. Sexual function was evaluated by the participant self-completion of a questionnaire based on the International Index of Erectile Function (IIEF) 711/929. Seventy-seven percent of participants returned the questionnaire. Data from 668 (72%) respondents were included. Thirty-three percent (95%CI: 29.4-36.5%) had moderate/severe erectile dysfunction (EDF) and 24% (95%CI: 20.9-27.3%) had moderate to severe impairment of sexual desire. Variables significantly associated with EDF in multivariable analysis were older age (greater than 40 years), heterosexual status, non-alcohol drinking status, depression, antidepressants, psychotropic medications and duration of ARV therapy. Low sexual desire (LSD) was associated with older age (greater than 40 years), depression and black African ethnicity. We establish that EDF and LSD are common in both ARV naïve and ARV experienced, HIV-positive individuals. Erectile dysfunction was associated with long duration of ARV treatment, with a significantly increased risk of dysfunction in the quartile with the longest period of exposure. No significant association was seen with specific classes of anti-retrovirals. Older age, and depression were the variables most consistently associated with both EDF and LSD. [ABSTRACT FROM AUTHOR]
Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Sexual dysfunction in HIV-positive men is multi-factorial: A study of prevalence and associated factors.
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  Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Sep2007, Vol. 19 Issue 8, p955-965. 11p. 1 Chart, 2 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22HIV-positive+men%22">HIV-positive men</searchLink><br /><searchLink fieldCode="DE" term="%22Sexual+dysfunction%22">Sexual dysfunction</searchLink><br /><searchLink fieldCode="DE" term="%22HIV-positive+persons%22">HIV-positive persons</searchLink><br /><searchLink fieldCode="DE" term="%22Factor+analysis%22">Factor analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+prevalence%22">Disease prevalence</searchLink><br /><searchLink fieldCode="DE" term="%22Epidemiology%22">Epidemiology</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink><br /><searchLink fieldCode="DE" term="%22HIV+infections%22">HIV infections</searchLink><br /><searchLink fieldCode="DE" term="%22AIDS+prevention%22">AIDS prevention</searchLink>
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  Data: To establish the prevalence of sexual dysfunction amongst HIV-positive men and to determine the factors associated with dysfunction we conducted a cross-sectional study in seven European HIV treatment centres. Data on medical history, antiretroviral treatment and laboratory results were collected by interview and case record review. Sexual function was evaluated by the participant self-completion of a questionnaire based on the International Index of Erectile Function (IIEF) 711/929. Seventy-seven percent of participants returned the questionnaire. Data from 668 (72%) respondents were included. Thirty-three percent (95%CI: 29.4-36.5%) had moderate/severe erectile dysfunction (EDF) and 24% (95%CI: 20.9-27.3%) had moderate to severe impairment of sexual desire. Variables significantly associated with EDF in multivariable analysis were older age (greater than 40 years), heterosexual status, non-alcohol drinking status, depression, antidepressants, psychotropic medications and duration of ARV therapy. Low sexual desire (LSD) was associated with older age (greater than 40 years), depression and black African ethnicity. We establish that EDF and LSD are common in both ARV naïve and ARV experienced, HIV-positive individuals. Erectile dysfunction was associated with long duration of ARV treatment, with a significantly increased risk of dysfunction in the quartile with the longest period of exposure. No significant association was seen with specific classes of anti-retrovirals. Older age, and depression were the variables most consistently associated with both EDF and LSD. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1080/09540120701209847
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        Text: English
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      Pagination:
        PageCount: 11
        StartPage: 955
    Subjects:
      – SubjectFull: HIV-positive men
        Type: general
      – SubjectFull: Sexual dysfunction
        Type: general
      – SubjectFull: HIV-positive persons
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      – SubjectFull: Factor analysis
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      – SubjectFull: Disease prevalence
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      – SubjectFull: Epidemiology
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      – SubjectFull: Therapeutics
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      – SubjectFull: HIV infections
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      – SubjectFull: AIDS prevention
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      – SubjectFull: Europe
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              Text: Sep2007
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