Illness perception and health-related quality of life in multiple sclerosis.
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| Title: | Illness perception and health-related quality of life in multiple sclerosis. |
|---|---|
| Authors: | Spain, L. A., Tubridy, N., Kilpatrick, T. J., Adams, S. J., Holmes, A. C. N. |
| Source: | Acta Neurologica Scandinavica. Nov2007, Vol. 116 Issue 5, p293-299. 7p. 3 Charts, 1 Graph. |
| Subjects: | Multiple sclerosis, Quality of life, Mental health, Agitation (Psychology), Physiology |
| Geographic Terms: | Australia |
| Abstract: | Aims – A number of physical and psychological factors have been shown to affect health-related quality of life (HRQoL) in patients with multiple sclerosis (MS). Among these, the role of illness perceptions has not been established as an independent factor. This study, the first of its kind in an Australian population, aimed to use a large sample to determine the relative importance of individual factors to each domain of HRQoL, in particular the role of illness perception. Materials and methods – 580 patients with confirmed MS were assessed cross sectionally in a designated research clinic to determine the relative impact of physical factors (illness severity, duration, age, fatigue and pain) and psychological factors (mood, cognition and illness representations) on each domain of the SF-36. Results – Categorical regression analysis showed that a combination of physical and psychological factors predicted 38–71% of variance in HRQoL. Illness perception was shown to have an independent effect on HRQoL in MS. The Extended Disability Status Scale was a significant determinant in all domains except for mental health. Depression was less prevalent than anxiety, but had a greater effect on function. Conclusion – Illness perception is an independent factor contributing to HRQoL in people with MS. Individual domains of HRQoL are associated with different patterns of physical and psychological factors. In the domains of role and social function, activities most highly valued by patients with MS, depression, anxiety, fatigue and illness perceptions are key determinants, all of which have the potential to be improved through specific interventions. [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 26937261 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Illness perception and health-related quality of life in multiple sclerosis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Spain%2C+L%2E+A%2E%22">Spain, L. A.</searchLink><br /><searchLink fieldCode="AR" term="%22Tubridy%2C+N%2E%22">Tubridy, N.</searchLink><br /><searchLink fieldCode="AR" term="%22Kilpatrick%2C+T%2E+J%2E%22">Kilpatrick, T. J.</searchLink><br /><searchLink fieldCode="AR" term="%22Adams%2C+S%2E+J%2E%22">Adams, S. J.</searchLink><br /><searchLink fieldCode="AR" term="%22Holmes%2C+A%2E+C%2E+N%2E%22">Holmes, A. C. N.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Acta+Neurologica+Scandinavica%22">Acta Neurologica Scandinavica</searchLink>. Nov2007, Vol. 116 Issue 5, p293-299. 7p. 3 Charts, 1 Graph. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Multiple+sclerosis%22">Multiple sclerosis</searchLink><br /><searchLink fieldCode="DE" term="%22Quality+of+life%22">Quality of life</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+health%22">Mental health</searchLink><br /><searchLink fieldCode="DE" term="%22Agitation+%28Psychology%29%22">Agitation (Psychology)</searchLink><br /><searchLink fieldCode="DE" term="%22Physiology%22">Physiology</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Australia%22">Australia</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Aims – A number of physical and psychological factors have been shown to affect health-related quality of life (HRQoL) in patients with multiple sclerosis (MS). Among these, the role of illness perceptions has not been established as an independent factor. This study, the first of its kind in an Australian population, aimed to use a large sample to determine the relative importance of individual factors to each domain of HRQoL, in particular the role of illness perception. Materials and methods – 580 patients with confirmed MS were assessed cross sectionally in a designated research clinic to determine the relative impact of physical factors (illness severity, duration, age, fatigue and pain) and psychological factors (mood, cognition and illness representations) on each domain of the SF-36. Results – Categorical regression analysis showed that a combination of physical and psychological factors predicted 38–71% of variance in HRQoL. Illness perception was shown to have an independent effect on HRQoL in MS. The Extended Disability Status Scale was a significant determinant in all domains except for mental health. Depression was less prevalent than anxiety, but had a greater effect on function. Conclusion – Illness perception is an independent factor contributing to HRQoL in people with MS. Individual domains of HRQoL are associated with different patterns of physical and psychological factors. In the domains of role and social function, activities most highly valued by patients with MS, depression, anxiety, fatigue and illness perceptions are key determinants, all of which have the potential to be improved through specific interventions. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/j.1600-0404.2007.00895.x Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 293 Subjects: – SubjectFull: Multiple sclerosis Type: general – SubjectFull: Quality of life Type: general – SubjectFull: Mental health Type: general – SubjectFull: Agitation (Psychology) Type: general – SubjectFull: Physiology Type: general – SubjectFull: Australia Type: general Titles: – TitleFull: Illness perception and health-related quality of life in multiple sclerosis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Spain, L. A. – PersonEntity: Name: NameFull: Tubridy, N. – PersonEntity: Name: NameFull: Kilpatrick, T. J. – PersonEntity: Name: NameFull: Adams, S. J. – PersonEntity: Name: NameFull: Holmes, A. C. N. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: Nov2007 Type: published Y: 2007 Identifiers: – Type: issn-print Value: 00016314 Numbering: – Type: volume Value: 116 – Type: issue Value: 5 Titles: – TitleFull: Acta Neurologica Scandinavica Type: main |
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