Sentinel lymph node biopsy as an alternative to wait and see policy in patients with small T1 oral cavity squamous cell carcinoma.

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Title: Sentinel lymph node biopsy as an alternative to wait and see policy in patients with small T1 oral cavity squamous cell carcinoma.
Authors: Keski-säntti, >Harri (AUTHOR), Kontio, Risto (AUTHOR), Leivo, Ilmo (AUTHOR), Törnwall, Jyrki (AUTHOR), Mätzke, Sorjo (AUTHOR), Mäkitie, Antti A. (AUTHOR), Atula, Timo (AUTHOR)
Source: Acta Oto-Laryngologica. Jan2008, Vol. 128 Issue 1, p98-102. 5p. 2 Color Photographs.
Subjects: Lymph nodes, Biopsy, Squamous cell carcinoma, Medical protocols, Cancer patients, Metastasis
Abstract: Conclusion. Although sentinel lymph node (SLN) biopsy is not yet validated for clinical use to replace elective neck dissection in patients with oral squamous cell carcinoma, it can be recommended for patients who do not fulfil the criteria for elective neck treatment according to current treatment protocols. Objective. To examine the benefits of SLN biopsy in oral cancer patients who have a small risk for occult metastasis and therefore are not considered candidates for elective neck treatment. Patients and methods. Thirteen consecutive patients with a small T1 oral cavity squamous cell carcinoma, clinically staged N0, and who did not meet the indications for elective neck treatment, underwent SLN biopsy. The SLNs were cut at 1-2 mm intervals and stained with haematoxylin and eosin and cytokeratin AE1/AE3. Results. Histopathological examination of SLNs revealed micrometastases in two patients. A selective neck dissection was performed on these patients and no further metastases were encountered. All patients had a minimum follow-up of 12 months and no cervical or other recurrences were encountered. [ABSTRACT FROM AUTHOR]
Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
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  Data: Sentinel lymph node biopsy as an alternative to wait and see policy in patients with small T1 oral cavity squamous cell carcinoma.
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  Data: <searchLink fieldCode="AR" term="%22Keski-säntti%2C+>Harri%22">Keski-säntti, >Harri</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kontio%2C+Risto%22">Kontio, Risto</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Leivo%2C+Ilmo%22">Leivo, Ilmo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Törnwall%2C+Jyrki%22">Törnwall, Jyrki</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mätzke%2C+Sorjo%22">Mätzke, Sorjo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mäkitie%2C+Antti+A%2E%22">Mäkitie, Antti A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Atula%2C+Timo%22">Atula, Timo</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Acta+Oto-Laryngologica%22">Acta Oto-Laryngologica</searchLink>. Jan2008, Vol. 128 Issue 1, p98-102. 5p. 2 Color Photographs.
– Name: Subject
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  Data: <searchLink fieldCode="DE" term="%22Lymph+nodes%22">Lymph nodes</searchLink><br /><searchLink fieldCode="DE" term="%22Biopsy%22">Biopsy</searchLink><br /><searchLink fieldCode="DE" term="%22Squamous+cell+carcinoma%22">Squamous cell carcinoma</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+protocols%22">Medical protocols</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+patients%22">Cancer patients</searchLink><br /><searchLink fieldCode="DE" term="%22Metastasis%22">Metastasis</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Conclusion. Although sentinel lymph node (SLN) biopsy is not yet validated for clinical use to replace elective neck dissection in patients with oral squamous cell carcinoma, it can be recommended for patients who do not fulfil the criteria for elective neck treatment according to current treatment protocols. Objective. To examine the benefits of SLN biopsy in oral cancer patients who have a small risk for occult metastasis and therefore are not considered candidates for elective neck treatment. Patients and methods. Thirteen consecutive patients with a small T1 oral cavity squamous cell carcinoma, clinically staged N0, and who did not meet the indications for elective neck treatment, underwent SLN biopsy. The SLNs were cut at 1-2 mm intervals and stained with haematoxylin and eosin and cytokeratin AE1/AE3. Results. Histopathological examination of SLNs revealed micrometastases in two patients. A selective neck dissection was performed on these patients and no further metastases were encountered. All patients had a minimum follow-up of 12 months and no cervical or other recurrences were encountered. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1080/00016480701362002
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      – Code: eng
        Text: English
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      – SubjectFull: Lymph nodes
        Type: general
      – SubjectFull: Biopsy
        Type: general
      – SubjectFull: Squamous cell carcinoma
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      – SubjectFull: Medical protocols
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      – SubjectFull: Metastasis
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              Text: Jan2008
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              Y: 2008
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