View in EDS PDF Full Text

Diffusion tensor imaging in patients with primary cervical dystonia and in patients with blepharospasm.

Saved in:
Bibliographic Details
Title: Diffusion tensor imaging in patients with primary cervical dystonia and in patients with blepharospasm.
Authors: Fabbrini, G., Pantano, P., Totaro, P., Calistri, V., Colosimo, C., Carmellini, M., Defazio, G., Berardelli, A.
Source: European Journal of Neurology. Feb2008, Vol. 15 Issue 2, p185-189. 5p. 2 Charts.
Subjects: Imaging compatibility of biomedical materials, Diffusion tensor imaging, Brain, Dystonia, Anisotropy
Abstract: Diffusion tensor imaging (DTI) analyses the movement of water molecules within the cerebral white matter thus providing information on ultrastructural brain changes. We studied 18 patients with cervical dystonia (CD), 16 with blepharospasm (BSP) and 35 years age-matched healthy controls. DTI data were obtained with a Philips 1.5 Tesla scanner and then processed to obtain maps of fractional anisotropy (FA) and mean diffusivity (MD). Twenty-three square regions of interest of uniform size were positioned on the FA maps and then automatically transferred to the MD maps. FA and MD values in the corpus callosum, left and right putamen, right caudate, left and right pre-frontal cortical area and left supplementary motor area in CD patients differed significantly from those in healthy controls. No significant regional differences were found between patients with BSP and healthy controls. In the CD group, age, duration and severity of dystonia did not correlate with regional FA/MD values, whereas the duration of botulinum toxin treatment correlated significantly with the MD value in the right-pre-frontal cortex. The abnormal DTI findings in patients with CD suggest the presence of brain ultrastructural changes in adult-onset primary CD. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 28530949
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Diffusion tensor imaging in patients with primary cervical dystonia and in patients with blepharospasm.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Fabbrini%2C+G%2E%22">Fabbrini, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Pantano%2C+P%2E%22">Pantano, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Totaro%2C+P%2E%22">Totaro, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Calistri%2C+V%2E%22">Calistri, V.</searchLink><br /><searchLink fieldCode="AR" term="%22Colosimo%2C+C%2E%22">Colosimo, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Carmellini%2C+M%2E%22">Carmellini, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Defazio%2C+G%2E%22">Defazio, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Berardelli%2C+A%2E%22">Berardelli, A.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neurology%22">European Journal of Neurology</searchLink>. Feb2008, Vol. 15 Issue 2, p185-189. 5p. 2 Charts.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Imaging+compatibility+of+biomedical+materials%22">Imaging compatibility of biomedical materials</searchLink><br /><searchLink fieldCode="DE" term="%22Diffusion+tensor+imaging%22">Diffusion tensor imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Brain%22">Brain</searchLink><br /><searchLink fieldCode="DE" term="%22Dystonia%22">Dystonia</searchLink><br /><searchLink fieldCode="DE" term="%22Anisotropy%22">Anisotropy</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Diffusion tensor imaging (DTI) analyses the movement of water molecules within the cerebral white matter thus providing information on ultrastructural brain changes. We studied 18 patients with cervical dystonia (CD), 16 with blepharospasm (BSP) and 35 years age-matched healthy controls. DTI data were obtained with a Philips 1.5 Tesla scanner and then processed to obtain maps of fractional anisotropy (FA) and mean diffusivity (MD). Twenty-three square regions of interest of uniform size were positioned on the FA maps and then automatically transferred to the MD maps. FA and MD values in the corpus callosum, left and right putamen, right caudate, left and right pre-frontal cortical area and left supplementary motor area in CD patients differed significantly from those in healthy controls. No significant regional differences were found between patients with BSP and healthy controls. In the CD group, age, duration and severity of dystonia did not correlate with regional FA/MD values, whereas the duration of botulinum toxin treatment correlated significantly with the MD value in the right-pre-frontal cortex. The abnormal DTI findings in patients with CD suggest the presence of brain ultrastructural changes in adult-onset primary CD. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=28530949
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/j.1468-1331.2007.02034.x
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 5
        StartPage: 185
    Subjects:
      – SubjectFull: Imaging compatibility of biomedical materials
        Type: general
      – SubjectFull: Diffusion tensor imaging
        Type: general
      – SubjectFull: Brain
        Type: general
      – SubjectFull: Dystonia
        Type: general
      – SubjectFull: Anisotropy
        Type: general
    Titles:
      – TitleFull: Diffusion tensor imaging in patients with primary cervical dystonia and in patients with blepharospasm.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Fabbrini, G.
      – PersonEntity:
          Name:
            NameFull: Pantano, P.
      – PersonEntity:
          Name:
            NameFull: Totaro, P.
      – PersonEntity:
          Name:
            NameFull: Calistri, V.
      – PersonEntity:
          Name:
            NameFull: Colosimo, C.
      – PersonEntity:
          Name:
            NameFull: Carmellini, M.
      – PersonEntity:
          Name:
            NameFull: Defazio, G.
      – PersonEntity:
          Name:
            NameFull: Berardelli, A.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: Feb2008
              Type: published
              Y: 2008
          Identifiers:
            – Type: issn-print
              Value: 13515101
          Numbering:
            – Type: volume
              Value: 15
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: European Journal of Neurology
              Type: main
ResultId 1