View in EDS PDF Full Text

Thyrotrophin in the pars tuberalis triggers photoperiodic response.

Saved in:
Bibliographic Details
Title: Thyrotrophin in the pars tuberalis triggers photoperiodic response.
Authors: Nakao, Nobuhiro, Ono, Hiroko, Yamamura, Takashi, Anraku, Tsubasa, Takagi, Tsuyoshi, Higashi, Kumiko, Yasuo, Shinobu, Katou, Yasuhiro, Kageyama, Saburo, Uno, Yumiko, Kasukawa, Takeya, Iigo, Masayuki, Sharp, Peter J., Iwasawa, Atsushi, Suzuki, Yutaka, Sugano, Sumio, Niimi, Teruyuki, Mizutani, Makoto, Namikawa, Takao, Ebihara, Shizufumi
Source: Nature. 3/20/2008, Vol. 452 Issue 7185, p317-322. 6p. 5 Graphs.
Subjects: Hypothalamus, Japanese quail, Animal breeding, Thyroid hormones, Gene expression, Pituitary hormones, Endocrine glands, Genetic regulation, Thyrotropin, Cyclic adenylic acid
Abstract: Molecular mechanisms regulating animal seasonal breeding in response to changing photoperiod are not well understood. Rapid induction of gene expression of thyroid-hormone-activating enzyme (type 2 deiodinase, DIO2) in the mediobasal hypothalamus (MBH) of the Japanese quail (Coturnix japonica) is the earliest event yet recorded in the photoperiodic signal transduction pathway. Here we show cascades of gene expression in the quail MBH associated with the initiation of photoinduced secretion of luteinizing hormone. We identified two waves of gene expression. The first was initiated about 14 h after dawn of the first long day and included increased thyrotrophin (TSH) β-subunit expression in the pars tuberalis; the second occurred approximately 4 h later and included increased expression of DIO2. Intracerebroventricular (ICV) administration of TSH to short-day quail stimulated gonadal growth and expression of DIO2 which was shown to be mediated through a TSH receptor–cyclic AMP (cAMP) signalling pathway. Increased TSH in the pars tuberalis therefore seems to trigger long-day photoinduced seasonal breeding. [ABSTRACT FROM AUTHOR]
Copyright of Nature is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 31343712
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Thyrotrophin in the pars tuberalis triggers photoperiodic response.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Nakao%2C+Nobuhiro%22">Nakao, Nobuhiro</searchLink><br /><searchLink fieldCode="AR" term="%22Ono%2C+Hiroko%22">Ono, Hiroko</searchLink><br /><searchLink fieldCode="AR" term="%22Yamamura%2C+Takashi%22">Yamamura, Takashi</searchLink><br /><searchLink fieldCode="AR" term="%22Anraku%2C+Tsubasa%22">Anraku, Tsubasa</searchLink><br /><searchLink fieldCode="AR" term="%22Takagi%2C+Tsuyoshi%22">Takagi, Tsuyoshi</searchLink><br /><searchLink fieldCode="AR" term="%22Higashi%2C+Kumiko%22">Higashi, Kumiko</searchLink><br /><searchLink fieldCode="AR" term="%22Yasuo%2C+Shinobu%22">Yasuo, Shinobu</searchLink><br /><searchLink fieldCode="AR" term="%22Katou%2C+Yasuhiro%22">Katou, Yasuhiro</searchLink><br /><searchLink fieldCode="AR" term="%22Kageyama%2C+Saburo%22">Kageyama, Saburo</searchLink><br /><searchLink fieldCode="AR" term="%22Uno%2C+Yumiko%22">Uno, Yumiko</searchLink><br /><searchLink fieldCode="AR" term="%22Kasukawa%2C+Takeya%22">Kasukawa, Takeya</searchLink><br /><searchLink fieldCode="AR" term="%22Iigo%2C+Masayuki%22">Iigo, Masayuki</searchLink><br /><searchLink fieldCode="AR" term="%22Sharp%2C+Peter+J%2E%22">Sharp, Peter J.</searchLink><br /><searchLink fieldCode="AR" term="%22Iwasawa%2C+Atsushi%22">Iwasawa, Atsushi</searchLink><br /><searchLink fieldCode="AR" term="%22Suzuki%2C+Yutaka%22">Suzuki, Yutaka</searchLink><br /><searchLink fieldCode="AR" term="%22Sugano%2C+Sumio%22">Sugano, Sumio</searchLink><br /><searchLink fieldCode="AR" term="%22Niimi%2C+Teruyuki%22">Niimi, Teruyuki</searchLink><br /><searchLink fieldCode="AR" term="%22Mizutani%2C+Makoto%22">Mizutani, Makoto</searchLink><br /><searchLink fieldCode="AR" term="%22Namikawa%2C+Takao%22">Namikawa, Takao</searchLink><br /><searchLink fieldCode="AR" term="%22Ebihara%2C+Shizufumi%22">Ebihara, Shizufumi</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Nature%22">Nature</searchLink>. 3/20/2008, Vol. 452 Issue 7185, p317-322. 6p. 5 Graphs.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Hypothalamus%22">Hypothalamus</searchLink><br /><searchLink fieldCode="DE" term="%22Japanese+quail%22">Japanese quail</searchLink><br /><searchLink fieldCode="DE" term="%22Animal+breeding%22">Animal breeding</searchLink><br /><searchLink fieldCode="DE" term="%22Thyroid+hormones%22">Thyroid hormones</searchLink><br /><searchLink fieldCode="DE" term="%22Gene+expression%22">Gene expression</searchLink><br /><searchLink fieldCode="DE" term="%22Pituitary+hormones%22">Pituitary hormones</searchLink><br /><searchLink fieldCode="DE" term="%22Endocrine+glands%22">Endocrine glands</searchLink><br /><searchLink fieldCode="DE" term="%22Genetic+regulation%22">Genetic regulation</searchLink><br /><searchLink fieldCode="DE" term="%22Thyrotropin%22">Thyrotropin</searchLink><br /><searchLink fieldCode="DE" term="%22Cyclic+adenylic+acid%22">Cyclic adenylic acid</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Molecular mechanisms regulating animal seasonal breeding in response to changing photoperiod are not well understood. Rapid induction of gene expression of thyroid-hormone-activating enzyme (type 2 deiodinase, DIO2) in the mediobasal hypothalamus (MBH) of the Japanese quail (Coturnix japonica) is the earliest event yet recorded in the photoperiodic signal transduction pathway. Here we show cascades of gene expression in the quail MBH associated with the initiation of photoinduced secretion of luteinizing hormone. We identified two waves of gene expression. The first was initiated about 14 h after dawn of the first long day and included increased thyrotrophin (TSH) β-subunit expression in the pars tuberalis; the second occurred approximately 4 h later and included increased expression of DIO2. Intracerebroventricular (ICV) administration of TSH to short-day quail stimulated gonadal growth and expression of DIO2 which was shown to be mediated through a TSH receptor–cyclic AMP (cAMP) signalling pathway. Increased TSH in the pars tuberalis therefore seems to trigger long-day photoinduced seasonal breeding. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Nature is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=31343712
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/nature06738
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 6
        StartPage: 317
    Subjects:
      – SubjectFull: Hypothalamus
        Type: general
      – SubjectFull: Japanese quail
        Type: general
      – SubjectFull: Animal breeding
        Type: general
      – SubjectFull: Thyroid hormones
        Type: general
      – SubjectFull: Gene expression
        Type: general
      – SubjectFull: Pituitary hormones
        Type: general
      – SubjectFull: Endocrine glands
        Type: general
      – SubjectFull: Genetic regulation
        Type: general
      – SubjectFull: Thyrotropin
        Type: general
      – SubjectFull: Cyclic adenylic acid
        Type: general
    Titles:
      – TitleFull: Thyrotrophin in the pars tuberalis triggers photoperiodic response.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Nakao, Nobuhiro
      – PersonEntity:
          Name:
            NameFull: Ono, Hiroko
      – PersonEntity:
          Name:
            NameFull: Yamamura, Takashi
      – PersonEntity:
          Name:
            NameFull: Anraku, Tsubasa
      – PersonEntity:
          Name:
            NameFull: Takagi, Tsuyoshi
      – PersonEntity:
          Name:
            NameFull: Higashi, Kumiko
      – PersonEntity:
          Name:
            NameFull: Yasuo, Shinobu
      – PersonEntity:
          Name:
            NameFull: Katou, Yasuhiro
      – PersonEntity:
          Name:
            NameFull: Kageyama, Saburo
      – PersonEntity:
          Name:
            NameFull: Uno, Yumiko
      – PersonEntity:
          Name:
            NameFull: Kasukawa, Takeya
      – PersonEntity:
          Name:
            NameFull: Iigo, Masayuki
      – PersonEntity:
          Name:
            NameFull: Sharp, Peter J.
      – PersonEntity:
          Name:
            NameFull: Iwasawa, Atsushi
      – PersonEntity:
          Name:
            NameFull: Suzuki, Yutaka
      – PersonEntity:
          Name:
            NameFull: Sugano, Sumio
      – PersonEntity:
          Name:
            NameFull: Niimi, Teruyuki
      – PersonEntity:
          Name:
            NameFull: Mizutani, Makoto
      – PersonEntity:
          Name:
            NameFull: Namikawa, Takao
      – PersonEntity:
          Name:
            NameFull: Ebihara, Shizufumi
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 20
              M: 03
              Text: 3/20/2008
              Type: published
              Y: 2008
          Identifiers:
            – Type: issn-print
              Value: 00280836
          Numbering:
            – Type: volume
              Value: 452
            – Type: issue
              Value: 7185
          Titles:
            – TitleFull: Nature
              Type: main
ResultId 1