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Weight gain in bipolar disorder: pharmacological treatment as a contributing factor.

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Title: Weight gain in bipolar disorder: pharmacological treatment as a contributing factor.
Authors: Torrent, C. (AUTHOR), Amann, B. (AUTHOR), Sánchez‐Moreno, J. (AUTHOR), Colom, F. (AUTHOR), Reinares, M. (AUTHOR), Comes, M. (AUTHOR), Rosa, A. R. (AUTHOR), Scott, J. (AUTHOR), Vieta, E. (AUTHOR)
Source: Acta Psychiatrica Scandinavica. Jul2008, Vol. 118 Issue 1, p4-18. 15p. 1 Chart.
Subjects: Psychiatry, Body weight, Bipolar disorder, Obesity, Weight gain, Antipsychotic agents
Abstract: Objective: The aim of this paper was to review the association of most commonly used psychopharmacological drugs with weight gain in bipolar disorder. Method: Information was retrieved from a PubMed/Medline literature search reviewing weight gain in pharmacological studies in bipolar disorder. Results: Obesity and overweight in bipolar disorder are partly related to prescribed drugs with a strong effect of clozapine and olanzapine. Lesser but still relevant weight gain is caused by quetiapine, risperidone, lithium, valproate, gabapentin and by some antidepressants. Ziprasidone, aripiprazole, carbamazepine and lamotrigine do not seem to cause significant overweight. Conclusion: Careful monitoring of weight changes in patients before and after drug prescription should be implemented in the clinical routine and drugs which potentially cause weight gain should be avoided in overweight patients with bipolar disorder. Furthermore, eating habits and daily activities should be targeted as they may also have a significant impact on overall health and weight-related issues. [ABSTRACT FROM AUTHOR]
Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Weight gain in bipolar disorder: pharmacological treatment as a contributing factor.
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  Data: <searchLink fieldCode="AR" term="%22Torrent%2C+C%2E%22">Torrent, C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Amann%2C+B%2E%22">Amann, B.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sánchez‐Moreno%2C+J%2E%22">Sánchez‐Moreno, J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Colom%2C+F%2E%22">Colom, F.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Reinares%2C+M%2E%22">Reinares, M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Comes%2C+M%2E%22">Comes, M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rosa%2C+A%2E+R%2E%22">Rosa, A. R.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Scott%2C+J%2E%22">Scott, J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Vieta%2C+E%2E%22">Vieta, E.</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Acta+Psychiatrica+Scandinavica%22">Acta Psychiatrica Scandinavica</searchLink>. Jul2008, Vol. 118 Issue 1, p4-18. 15p. 1 Chart.
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  Data: <searchLink fieldCode="DE" term="%22Psychiatry%22">Psychiatry</searchLink><br /><searchLink fieldCode="DE" term="%22Body+weight%22">Body weight</searchLink><br /><searchLink fieldCode="DE" term="%22Bipolar+disorder%22">Bipolar disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Obesity%22">Obesity</searchLink><br /><searchLink fieldCode="DE" term="%22Weight+gain%22">Weight gain</searchLink><br /><searchLink fieldCode="DE" term="%22Antipsychotic+agents%22">Antipsychotic agents</searchLink>
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  Data: Objective: The aim of this paper was to review the association of most commonly used psychopharmacological drugs with weight gain in bipolar disorder. Method: Information was retrieved from a PubMed/Medline literature search reviewing weight gain in pharmacological studies in bipolar disorder. Results: Obesity and overweight in bipolar disorder are partly related to prescribed drugs with a strong effect of clozapine and olanzapine. Lesser but still relevant weight gain is caused by quetiapine, risperidone, lithium, valproate, gabapentin and by some antidepressants. Ziprasidone, aripiprazole, carbamazepine and lamotrigine do not seem to cause significant overweight. Conclusion: Careful monitoring of weight changes in patients before and after drug prescription should be implemented in the clinical routine and drugs which potentially cause weight gain should be avoided in overweight patients with bipolar disorder. Furthermore, eating habits and daily activities should be targeted as they may also have a significant impact on overall health and weight-related issues. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: Jul2008
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