Nitrous oxide for applying local anesthesia in nasal operations: a randomized placebo-controlled single-blinded study.

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Title: Nitrous oxide for applying local anesthesia in nasal operations: a randomized placebo-controlled single-blinded study.
Authors: Starck, Marit (AUTHOR), Tarkkila, Pekka (AUTHOR), Mäkitie, Antti A. (AUTHOR), Ylikoski, Jukka S. (AUTHOR), Bäck, >Leif J.J. (AUTHOR)
Source: Acta Oto-Laryngologica. Jul2008, Vol. 128 Issue 7, p772-777. 6p. 1 Color Photograph, 1 Chart, 4 Graphs.
Subjects: Nitrous oxide, Paranasal sinus surgery, Local anesthesia, Inhalation anesthesia, Paranasal sinuses
Abstract: Conclusions. In our study setting nitrous oxide (N2O) did not show any clinical benefit in discomfort experienced when applying local anesthesia for nasal operations. Further studies with longer inhalation times are needed to elucidate the role of N2O in application of local anesthesia in nasal surgery. Objectives. N2O inhalation reduces the discomfort experienced in various medical procedures. The objective of this study was to assess the suitability of N2O inhalation before application of local anesthesia for nasal procedures in outpatient surgery. Patients and methods. This was a prospective, randomized, single-blinded, placebo-controlled study at the Helsinki University Central Hospital, Finland. Ninety patients were randomly divided into three groups. Group A inhaled 10 breaths of 50% N2O/50% O2 through a nasal mask with a Porter 2000 MXR scavenging system before application of local nasal anesthesia, group B inhaled room air through the same mask and group C received only local anesthesia. A visual analog scale was used to assess pain, nausea, and discomfort related to the application of nasal anesthesia. Results. The N2O inhalation was easy to perform and well tolerated. The N2O inhalation before applying local anesthesia for nasal operations did not show any significant additional benefit in reducing pain or discomfort. [ABSTRACT FROM AUTHOR]
Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Nitrous oxide for applying local anesthesia in nasal operations: a randomized placebo-controlled single-blinded study.
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  Data: <searchLink fieldCode="JN" term="%22Acta+Oto-Laryngologica%22">Acta Oto-Laryngologica</searchLink>. Jul2008, Vol. 128 Issue 7, p772-777. 6p. 1 Color Photograph, 1 Chart, 4 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Nitrous+oxide%22">Nitrous oxide</searchLink><br /><searchLink fieldCode="DE" term="%22Paranasal+sinus+surgery%22">Paranasal sinus surgery</searchLink><br /><searchLink fieldCode="DE" term="%22Local+anesthesia%22">Local anesthesia</searchLink><br /><searchLink fieldCode="DE" term="%22Inhalation+anesthesia%22">Inhalation anesthesia</searchLink><br /><searchLink fieldCode="DE" term="%22Paranasal+sinuses%22">Paranasal sinuses</searchLink>
– Name: Abstract
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  Data: Conclusions. In our study setting nitrous oxide (N2O) did not show any clinical benefit in discomfort experienced when applying local anesthesia for nasal operations. Further studies with longer inhalation times are needed to elucidate the role of N2O in application of local anesthesia in nasal surgery. Objectives. N2O inhalation reduces the discomfort experienced in various medical procedures. The objective of this study was to assess the suitability of N2O inhalation before application of local anesthesia for nasal procedures in outpatient surgery. Patients and methods. This was a prospective, randomized, single-blinded, placebo-controlled study at the Helsinki University Central Hospital, Finland. Ninety patients were randomly divided into three groups. Group A inhaled 10 breaths of 50% N2O/50% O2 through a nasal mask with a Porter 2000 MXR scavenging system before application of local nasal anesthesia, group B inhaled room air through the same mask and group C received only local anesthesia. A visual analog scale was used to assess pain, nausea, and discomfort related to the application of nasal anesthesia. Results. The N2O inhalation was easy to perform and well tolerated. The N2O inhalation before applying local anesthesia for nasal operations did not show any significant additional benefit in reducing pain or discomfort. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1080/00016480701714319
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      – Code: eng
        Text: English
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        PageCount: 6
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      – SubjectFull: Nitrous oxide
        Type: general
      – SubjectFull: Paranasal sinus surgery
        Type: general
      – SubjectFull: Local anesthesia
        Type: general
      – SubjectFull: Inhalation anesthesia
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      – SubjectFull: Paranasal sinuses
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              Text: Jul2008
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              Y: 2008
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