Nitrous oxide for applying local anesthesia in nasal operations: a randomized placebo-controlled single-blinded study.
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| Title: | Nitrous oxide for applying local anesthesia in nasal operations: a randomized placebo-controlled single-blinded study. |
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| Authors: | Starck, Marit (AUTHOR), Tarkkila, Pekka (AUTHOR), Mäkitie, Antti A. (AUTHOR), Ylikoski, Jukka S. (AUTHOR), Bäck, >Leif J.J. (AUTHOR) |
| Source: | Acta Oto-Laryngologica. Jul2008, Vol. 128 Issue 7, p772-777. 6p. 1 Color Photograph, 1 Chart, 4 Graphs. |
| Subjects: | Nitrous oxide, Paranasal sinus surgery, Local anesthesia, Inhalation anesthesia, Paranasal sinuses |
| Abstract: | Conclusions. In our study setting nitrous oxide (N2O) did not show any clinical benefit in discomfort experienced when applying local anesthesia for nasal operations. Further studies with longer inhalation times are needed to elucidate the role of N2O in application of local anesthesia in nasal surgery. Objectives. N2O inhalation reduces the discomfort experienced in various medical procedures. The objective of this study was to assess the suitability of N2O inhalation before application of local anesthesia for nasal procedures in outpatient surgery. Patients and methods. This was a prospective, randomized, single-blinded, placebo-controlled study at the Helsinki University Central Hospital, Finland. Ninety patients were randomly divided into three groups. Group A inhaled 10 breaths of 50% N2O/50% O2 through a nasal mask with a Porter 2000 MXR scavenging system before application of local nasal anesthesia, group B inhaled room air through the same mask and group C received only local anesthesia. A visual analog scale was used to assess pain, nausea, and discomfort related to the application of nasal anesthesia. Results. The N2O inhalation was easy to perform and well tolerated. The N2O inhalation before applying local anesthesia for nasal operations did not show any significant additional benefit in reducing pain or discomfort. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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