Prevalence of CT-detected cerebral abnormalities in an elderly Swedish population sample.
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| Title: | Prevalence of CT-detected cerebral abnormalities in an elderly Swedish population sample. |
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| Authors: | Simoni, M., Pantoni, L., Pracucci, G., Palmertz, B., Guo, X., Gustafson, D., Skoog, I. |
| Source: | Acta Neurologica Scandinavica. Oct2008, Vol. 118 Issue 4, p260-267. 8p. 1 Diagram, 5 Charts. |
| Subjects: | Tomography, Biomineralization, Calcium in the body, Extrapyramidal tracts |
| Geographic Terms: | Sweden |
| Abstract: | Objective – To measure the prevalence of computed tomography (CT)-detected cerebral lesions in a population-based sample of elderly persons living in Göteborg, Sweden. Methods – Cerebral CT-scans were performed in the case of 466 women (mean age 74.3 ± 5.1 years) and 191 70-year-old men. A single rater assessed white matter lesions (WML) using four different scales, lacunar lesions, large infarcts, cortical atrophy, and basal ganglia calcifications. Results – White matter lesions frequency assessed by different scales ranged between 54.5% and 68.5%. Lacunar lesions were detected in 46.7% (30.1% had lacunes >5 mm) and cerebral infarcts in 3.0% of participants. Overall, 72.8% of participants evidenced cerebral vascular abnormalities. Severe cortical atrophy was more common in temporal (6.4%) and frontal (6.7%) lobes, than in parietal (1.7%) and occipital (1.1%) lobes. Basal ganglia calcifications were found in 38.7% of participants. WML, lacunar lesions, large infarcts, and degree of cortical atrophy correlated positively with age. More lacunes, basal ganglia calcifications, and occipital lobe atrophy were associated with male gender. Conclusions – Vascular and other brain lesions are very common on CT-scan in an elderly population, but large vascular lesions are rare. This study provides the first reference for the prevalence of CT-detected abnormalities in an elderly Swedish population. [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 34169013 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Prevalence of CT-detected cerebral abnormalities in an elderly Swedish population sample. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Simoni%2C+M%2E%22">Simoni, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Pantoni%2C+L%2E%22">Pantoni, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Pracucci%2C+G%2E%22">Pracucci, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Palmertz%2C+B%2E%22">Palmertz, B.</searchLink><br /><searchLink fieldCode="AR" term="%22Guo%2C+X%2E%22">Guo, X.</searchLink><br /><searchLink fieldCode="AR" term="%22Gustafson%2C+D%2E%22">Gustafson, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Skoog%2C+I%2E%22">Skoog, I.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Acta+Neurologica+Scandinavica%22">Acta Neurologica Scandinavica</searchLink>. Oct2008, Vol. 118 Issue 4, p260-267. 8p. 1 Diagram, 5 Charts. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Tomography%22">Tomography</searchLink><br /><searchLink fieldCode="DE" term="%22Biomineralization%22">Biomineralization</searchLink><br /><searchLink fieldCode="DE" term="%22Calcium+in+the+body%22">Calcium in the body</searchLink><br /><searchLink fieldCode="DE" term="%22Extrapyramidal+tracts%22">Extrapyramidal tracts</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Sweden%22">Sweden</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Objective – To measure the prevalence of computed tomography (CT)-detected cerebral lesions in a population-based sample of elderly persons living in Göteborg, Sweden. Methods – Cerebral CT-scans were performed in the case of 466 women (mean age 74.3 ± 5.1 years) and 191 70-year-old men. A single rater assessed white matter lesions (WML) using four different scales, lacunar lesions, large infarcts, cortical atrophy, and basal ganglia calcifications. Results – White matter lesions frequency assessed by different scales ranged between 54.5% and 68.5%. Lacunar lesions were detected in 46.7% (30.1% had lacunes >5 mm) and cerebral infarcts in 3.0% of participants. Overall, 72.8% of participants evidenced cerebral vascular abnormalities. Severe cortical atrophy was more common in temporal (6.4%) and frontal (6.7%) lobes, than in parietal (1.7%) and occipital (1.1%) lobes. Basal ganglia calcifications were found in 38.7% of participants. WML, lacunar lesions, large infarcts, and degree of cortical atrophy correlated positively with age. More lacunes, basal ganglia calcifications, and occipital lobe atrophy were associated with male gender. Conclusions – Vascular and other brain lesions are very common on CT-scan in an elderly population, but large vascular lesions are rare. This study provides the first reference for the prevalence of CT-detected abnormalities in an elderly Swedish population. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/j.1600-0404.2008.01010.x Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 260 Subjects: – SubjectFull: Tomography Type: general – SubjectFull: Biomineralization Type: general – SubjectFull: Calcium in the body Type: general – SubjectFull: Extrapyramidal tracts Type: general – SubjectFull: Sweden Type: general Titles: – TitleFull: Prevalence of CT-detected cerebral abnormalities in an elderly Swedish population sample. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Simoni, M. – PersonEntity: Name: NameFull: Pantoni, L. – PersonEntity: Name: NameFull: Pracucci, G. – PersonEntity: Name: NameFull: Palmertz, B. – PersonEntity: Name: NameFull: Guo, X. – PersonEntity: Name: NameFull: Gustafson, D. – PersonEntity: Name: NameFull: Skoog, I. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2008 Type: published Y: 2008 Identifiers: – Type: issn-print Value: 00016314 Numbering: – Type: volume Value: 118 – Type: issue Value: 4 Titles: – TitleFull: Acta Neurologica Scandinavica Type: main |
| ResultId | 1 |
