Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial.
Saved in:
| Title: | Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial. |
|---|---|
| Authors: | DeMatteo, Ronald P., Ballman, Karla V., Antonescu, Cristina R., Maki, Robert G., Pisters, Peter W. T., Demetri, George D., Blackstein, Martin E., Blanke, Charles D., von Mehren, Margaret, Brennan, Murray F., Patel, Shreyaskumar, McCarter, Martin D., Polikoff, Jonathan A., Tan, Benjamin R., Owzar, Kouros |
| Source: | Lancet. 3/28/2009, Vol. 373 Issue 9669, p1097-1104. 8p. 3 Graphs. |
| Subjects: | Imatinib, Gastrointestinal stromal tumors, Immunological adjuvants, Gastrointestinal tumors, Prevention of surgical complications, Protein-tyrosine kinase inhibitors, Gastrointestinal system, Randomized controlled trials, Tumor treatment |
| Abstract: | The article presents a study seeking to determine if an adjuvant treatment with imatinib mesylate would improve recurrence-free survival following resection of localized gastrointestinal stromal tumor. The methods of the randomized controlled trial involving patients who had complete resection of a primary gastrointestinal stromal tumor at least 3 cm in size is described. Researchers found imatinib significantly improved recurrence-free survival in patients compared to the placebo group. The findings indicate adjuvant imatinib therapy is safe and effective in improving survival after resection of primary gastrointestinal stromal tumor. |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 37260588 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22DeMatteo%2C+Ronald+P%2E%22">DeMatteo, Ronald P.</searchLink><br /><searchLink fieldCode="AR" term="%22Ballman%2C+Karla+V%2E%22">Ballman, Karla V.</searchLink><br /><searchLink fieldCode="AR" term="%22Antonescu%2C+Cristina+R%2E%22">Antonescu, Cristina R.</searchLink><br /><searchLink fieldCode="AR" term="%22Maki%2C+Robert+G%2E%22">Maki, Robert G.</searchLink><br /><searchLink fieldCode="AR" term="%22Pisters%2C+Peter+W%2E+T%2E%22">Pisters, Peter W. T.</searchLink><br /><searchLink fieldCode="AR" term="%22Demetri%2C+George+D%2E%22">Demetri, George D.</searchLink><br /><searchLink fieldCode="AR" term="%22Blackstein%2C+Martin+E%2E%22">Blackstein, Martin E.</searchLink><br /><searchLink fieldCode="AR" term="%22Blanke%2C+Charles+D%2E%22">Blanke, Charles D.</searchLink><br /><searchLink fieldCode="AR" term="%22von+Mehren%2C+Margaret%22">von Mehren, Margaret</searchLink><br /><searchLink fieldCode="AR" term="%22Brennan%2C+Murray+F%2E%22">Brennan, Murray F.</searchLink><br /><searchLink fieldCode="AR" term="%22Patel%2C+Shreyaskumar%22">Patel, Shreyaskumar</searchLink><br /><searchLink fieldCode="AR" term="%22McCarter%2C+Martin+D%2E%22">McCarter, Martin D.</searchLink><br /><searchLink fieldCode="AR" term="%22Polikoff%2C+Jonathan+A%2E%22">Polikoff, Jonathan A.</searchLink><br /><searchLink fieldCode="AR" term="%22Tan%2C+Benjamin+R%2E%22">Tan, Benjamin R.</searchLink><br /><searchLink fieldCode="AR" term="%22Owzar%2C+Kouros%22">Owzar, Kouros</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 3/28/2009, Vol. 373 Issue 9669, p1097-1104. 8p. 3 Graphs. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Imatinib%22">Imatinib</searchLink><br /><searchLink fieldCode="DE" term="%22Gastrointestinal+stromal+tumors%22">Gastrointestinal stromal tumors</searchLink><br /><searchLink fieldCode="DE" term="%22Immunological+adjuvants%22">Immunological adjuvants</searchLink><br /><searchLink fieldCode="DE" term="%22Gastrointestinal+tumors%22">Gastrointestinal tumors</searchLink><br /><searchLink fieldCode="DE" term="%22Prevention+of+surgical+complications%22">Prevention of surgical complications</searchLink><br /><searchLink fieldCode="DE" term="%22Protein-tyrosine+kinase+inhibitors%22">Protein-tyrosine kinase inhibitors</searchLink><br /><searchLink fieldCode="DE" term="%22Gastrointestinal+system%22">Gastrointestinal system</searchLink><br /><searchLink fieldCode="DE" term="%22Randomized+controlled+trials%22">Randomized controlled trials</searchLink><br /><searchLink fieldCode="DE" term="%22Tumor+treatment%22">Tumor treatment</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: The article presents a study seeking to determine if an adjuvant treatment with imatinib mesylate would improve recurrence-free survival following resection of localized gastrointestinal stromal tumor. The methods of the randomized controlled trial involving patients who had complete resection of a primary gastrointestinal stromal tumor at least 3 cm in size is described. Researchers found imatinib significantly improved recurrence-free survival in patients compared to the placebo group. The findings indicate adjuvant imatinib therapy is safe and effective in improving survival after resection of primary gastrointestinal stromal tumor. |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=37260588 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/S0140-6736(09)60500-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 1097 Subjects: – SubjectFull: Imatinib Type: general – SubjectFull: Gastrointestinal stromal tumors Type: general – SubjectFull: Immunological adjuvants Type: general – SubjectFull: Gastrointestinal tumors Type: general – SubjectFull: Prevention of surgical complications Type: general – SubjectFull: Protein-tyrosine kinase inhibitors Type: general – SubjectFull: Gastrointestinal system Type: general – SubjectFull: Randomized controlled trials Type: general – SubjectFull: Tumor treatment Type: general Titles: – TitleFull: Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: DeMatteo, Ronald P. – PersonEntity: Name: NameFull: Ballman, Karla V. – PersonEntity: Name: NameFull: Antonescu, Cristina R. – PersonEntity: Name: NameFull: Maki, Robert G. – PersonEntity: Name: NameFull: Pisters, Peter W. T. – PersonEntity: Name: NameFull: Demetri, George D. – PersonEntity: Name: NameFull: Blackstein, Martin E. – PersonEntity: Name: NameFull: Blanke, Charles D. – PersonEntity: Name: NameFull: von Mehren, Margaret – PersonEntity: Name: NameFull: Brennan, Murray F. – PersonEntity: Name: NameFull: Patel, Shreyaskumar – PersonEntity: Name: NameFull: McCarter, Martin D. – PersonEntity: Name: NameFull: Polikoff, Jonathan A. – PersonEntity: Name: NameFull: Tan, Benjamin R. – PersonEntity: Name: NameFull: Owzar, Kouros IsPartOfRelationships: – BibEntity: Dates: – D: 28 M: 03 Text: 3/28/2009 Type: published Y: 2009 Identifiers: – Type: issn-print Value: 01406736 Numbering: – Type: volume Value: 373 – Type: issue Value: 9669 Titles: – TitleFull: Lancet Type: main |
| ResultId | 1 |
