Antiretroviral treatments used among adults with HIV infection in Europe.

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Title: Antiretroviral treatments used among adults with HIV infection in Europe.
Authors: Colebunders, R., Schrooten, W., Dreezen, C., Baratta, C., Florence, E., Finazzi, R., Wilkins, E., Hemmer, R., Fleerackers, Y., Andragetti, R., Borchert, M.
Source: AIDS Care. Feb2001, Vol. 13 Issue 1, p5-14. 10p. 5 Charts, 1 Graph.
Subjects: HIV infections, Therapeutics, Medical centers
Geographic Terms: Europe
Abstract: International guidelines for the treatment of human immunodeficiency virus (HIV) infection change rapidly. They are mainly based on results from large-scale randomized clinical trials, but also on hypotheses. The objective of the study was to look at the use of antiretrovirals (ARVs) in different HIV treatment centres in Europe. Between August 1996 and September 1997 self-administered anonymous questionnaires were distributed to persons with HIV infection at inpatient and outpatient departments in 11 European countries; 1,366 people completed the questionnaire. Important differences in use of ARVs were noted between different centres. Zidovudine was the drug that was used predominantly in all countries and by 77% of all patients; the use of didanosine, zalcitabine and stavudine differed widely. Use of ARVs was found to be lower for people who reported intravenous drug use (compared to homosexual transmission), people with a low education level, and those with a monthly income lower than 992 Euro. The use of a protease inhibitor containing ARV treatment regimen was significantly lower in the centres in the south of Europe. Between 1996 and 1997, many persons with HIV infection in Europe received a suboptimal ARV treatment regimen. Use of ARVs should be improved for intravenous drug users, persons with lower educational level and lower income. [ABSTRACT FROM AUTHOR]
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  Data: Antiretroviral treatments used among adults with HIV infection in Europe.
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  Data: <searchLink fieldCode="AR" term="%22Colebunders%2C+R%2E%22">Colebunders, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Schrooten%2C+W%2E%22">Schrooten, W.</searchLink><br /><searchLink fieldCode="AR" term="%22Dreezen%2C+C%2E%22">Dreezen, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Baratta%2C+C%2E%22">Baratta, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Florence%2C+E%2E%22">Florence, E.</searchLink><br /><searchLink fieldCode="AR" term="%22Finazzi%2C+R%2E%22">Finazzi, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Wilkins%2C+E%2E%22">Wilkins, E.</searchLink><br /><searchLink fieldCode="AR" term="%22Hemmer%2C+R%2E%22">Hemmer, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Fleerackers%2C+Y%2E%22">Fleerackers, Y.</searchLink><br /><searchLink fieldCode="AR" term="%22Andragetti%2C+R%2E%22">Andragetti, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Borchert%2C+M%2E%22">Borchert, M.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Feb2001, Vol. 13 Issue 1, p5-14. 10p. 5 Charts, 1 Graph.
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  Data: <searchLink fieldCode="DE" term="%22HIV+infections%22">HIV infections</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+centers%22">Medical centers</searchLink>
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  Data: International guidelines for the treatment of human immunodeficiency virus (HIV) infection change rapidly. They are mainly based on results from large-scale randomized clinical trials, but also on hypotheses. The objective of the study was to look at the use of antiretrovirals (ARVs) in different HIV treatment centres in Europe. Between August 1996 and September 1997 self-administered anonymous questionnaires were distributed to persons with HIV infection at inpatient and outpatient departments in 11 European countries; 1,366 people completed the questionnaire. Important differences in use of ARVs were noted between different centres. Zidovudine was the drug that was used predominantly in all countries and by 77% of all patients; the use of didanosine, zalcitabine and stavudine differed widely. Use of ARVs was found to be lower for people who reported intravenous drug use (compared to homosexual transmission), people with a low education level, and those with a monthly income lower than 992 Euro. The use of a protease inhibitor containing ARV treatment regimen was significantly lower in the centres in the south of Europe. Between 1996 and 1997, many persons with HIV infection in Europe received a suboptimal ARV treatment regimen. Use of ARVs should be improved for intravenous drug users, persons with lower educational level and lower income. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: Feb2001
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