Basilar artery atherosclerotic disease is related to subacute lesion volume increase in pontine base infarction.
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| Title: | Basilar artery atherosclerotic disease is related to subacute lesion volume increase in pontine base infarction. |
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| Authors: | Kim, J. S., Cho, K.-H., Kang, D.-W., Kwon, S. U., Suh, D. C. |
| Source: | Acta Neurologica Scandinavica. Aug2009, Vol. 120 Issue 2, p88-93. 6p. 1 Black and White Photograph, 1 Chart. |
| Subjects: | Atherosclerosis, Vertebrobasilar insufficiency, Magnetic resonance imaging, Neurological errors, Infarction |
| Abstract: | Background – Although basilar artery atherosclerotic disease (BAD) is frequent in patients with pontine base infarction, it remains unknown whether BAD is related to the lesion size or clinical outcome. Methods – We studied 56 patients with unilateral pontine base infarction who underwent (i) diffusion-weighted MRI within 48 h after stroke onset and (ii) follow-up MRI and MR angiography in the subacute stage. Neurologic progression was defined as increased National Institutes of Health Stroke Scale score by ≥ 2 during admission. Clinical outcome was dichotomized as good and poor (≥ 3) according to the modified Rankin Scale at 1 month after stroke onset. Results – Twenty-two patients (39%) had BAD and 15 patients (27%) had neurologic progression. Follow-up MRI performed at median 3.5 ± 1.1 days after the initial MRI showed the lesion volume significantly increased ( P < 0.001). The BAD was not significantly related to demographic characteristics, risk factors, initial and follow-up lesion volume, neurologic progression and clinical outcome, but was closely related to the subacute increase in lesion volume ( P = 0.004 for 20% increase, P = 0.029 for 50% increase). Conclusions – BAD is related to subacute increase in lesion volume, but not to ultimate poor clinical outcome in patients with pontine base infarction. [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 43112776 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Basilar artery atherosclerotic disease is related to subacute lesion volume increase in pontine base infarction. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Kim%2C+J%2E+S%2E%22">Kim, J. S.</searchLink><br /><searchLink fieldCode="AR" term="%22Cho%2C+K%2E-H%2E%22">Cho, K.-H.</searchLink><br /><searchLink fieldCode="AR" term="%22Kang%2C+D%2E-W%2E%22">Kang, D.-W.</searchLink><br /><searchLink fieldCode="AR" term="%22Kwon%2C+S%2E+U%2E%22">Kwon, S. U.</searchLink><br /><searchLink fieldCode="AR" term="%22Suh%2C+D%2E+C%2E%22">Suh, D. C.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Acta+Neurologica+Scandinavica%22">Acta Neurologica Scandinavica</searchLink>. Aug2009, Vol. 120 Issue 2, p88-93. 6p. 1 Black and White Photograph, 1 Chart. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Atherosclerosis%22">Atherosclerosis</searchLink><br /><searchLink fieldCode="DE" term="%22Vertebrobasilar+insufficiency%22">Vertebrobasilar insufficiency</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Neurological+errors%22">Neurological errors</searchLink><br /><searchLink fieldCode="DE" term="%22Infarction%22">Infarction</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Background – Although basilar artery atherosclerotic disease (BAD) is frequent in patients with pontine base infarction, it remains unknown whether BAD is related to the lesion size or clinical outcome. Methods – We studied 56 patients with unilateral pontine base infarction who underwent (i) diffusion-weighted MRI within 48 h after stroke onset and (ii) follow-up MRI and MR angiography in the subacute stage. Neurologic progression was defined as increased National Institutes of Health Stroke Scale score by ≥ 2 during admission. Clinical outcome was dichotomized as good and poor (≥ 3) according to the modified Rankin Scale at 1 month after stroke onset. Results – Twenty-two patients (39%) had BAD and 15 patients (27%) had neurologic progression. Follow-up MRI performed at median 3.5 ± 1.1 days after the initial MRI showed the lesion volume significantly increased ( P < 0.001). The BAD was not significantly related to demographic characteristics, risk factors, initial and follow-up lesion volume, neurologic progression and clinical outcome, but was closely related to the subacute increase in lesion volume ( P = 0.004 for 20% increase, P = 0.029 for 50% increase). Conclusions – BAD is related to subacute increase in lesion volume, but not to ultimate poor clinical outcome in patients with pontine base infarction. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/j.1600-0404.2008.01124.x Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 6 StartPage: 88 Subjects: – SubjectFull: Atherosclerosis Type: general – SubjectFull: Vertebrobasilar insufficiency Type: general – SubjectFull: Magnetic resonance imaging Type: general – SubjectFull: Neurological errors Type: general – SubjectFull: Infarction Type: general Titles: – TitleFull: Basilar artery atherosclerotic disease is related to subacute lesion volume increase in pontine base infarction. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kim, J. S. – PersonEntity: Name: NameFull: Cho, K.-H. – PersonEntity: Name: NameFull: Kang, D.-W. – PersonEntity: Name: NameFull: Kwon, S. U. – PersonEntity: Name: NameFull: Suh, D. C. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: Aug2009 Type: published Y: 2009 Identifiers: – Type: issn-print Value: 00016314 Numbering: – Type: volume Value: 120 – Type: issue Value: 2 Titles: – TitleFull: Acta Neurologica Scandinavica Type: main |
| ResultId | 1 |
