Bibliographic Details
| Title: |
Leptin-regulated endocannabinoids are involved in maintaining food intake. |
| Authors: |
Di Marzo, Vincenzo, Goparaju, Sraven K., Wang, Lei, Liu, Jie, Batkai, Sandor, Jarai, Zoltan, Fezza, Filomena, Miura, Grant I., Palmiter, Richard D., Sugiura, Takayuki, Kunos, George |
| Source: |
Nature. 4/12/2001, Vol. 410 Issue 6830, p822. 4p. 9 Graphs. |
| Subjects: |
Leptin, Hypothalamic hormones, Cannabinoids, Hypothalamus |
| Abstract: |
Presents a study which investigates whether leptin may similarly regulate hypothalamic endocannabinoids in mice. Experiment where mice were injected with leptin; Indication from findings that endocannabinoids in the hypothalamus may tonically activate CB1 receptors to maintain food intake and form part of the neural circuitry regulated by leptin. |
| Database: |
Psychology and Behavioral Sciences Collection |