Leptin-regulated endocannabinoids are involved in maintaining food intake.
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| Title: | Leptin-regulated endocannabinoids are involved in maintaining food intake. |
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| Authors: | Di Marzo, Vincenzo, Goparaju, Sraven K., Wang, Lei, Liu, Jie, Batkai, Sandor, Jarai, Zoltan, Fezza, Filomena, Miura, Grant I., Palmiter, Richard D., Sugiura, Takayuki, Kunos, George |
| Source: | Nature. 4/12/2001, Vol. 410 Issue 6830, p822. 4p. 9 Graphs. |
| Subjects: | Leptin, Hypothalamic hormones, Cannabinoids, Hypothalamus |
| Abstract: | Presents a study which investigates whether leptin may similarly regulate hypothalamic endocannabinoids in mice. Experiment where mice were injected with leptin; Indication from findings that endocannabinoids in the hypothalamus may tonically activate CB1 receptors to maintain food intake and form part of the neural circuitry regulated by leptin. |
| Database: | Psychology and Behavioral Sciences Collection |
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