View in EDS PDF Full Text

Induction of the mammalian node requires Arkadia function in the extraembryonic lineages.

Saved in:
Bibliographic Details
Title: Induction of the mammalian node requires Arkadia function in the extraembryonic lineages.
Authors: Episkopou, Vasso, Arkell, Ruth, Timmons, Paula M., Walsh, James J., Andrew, Rebecca L., Swan, Daniel
Source: Nature. 4/12/2001, Vol. 410 Issue 6830, p825. 6p. 27 Color Photographs, 1 Black and White Photograph, 2 Diagrams.
Subjects: Embryonic stem cells, Genetic mutation, Mutagenesis, Transforming growth factors
Abstract: Presents a study of arkadia, a recessive lethal mutation generated using gene-trap mutagenesis in embryonic stem cells. Analysis with chimaeras, which shows that Arkadia functions within extraembryonic tissues; Results which show that Arkadia interacts genetically with the transforming growth factor beta-like factor Nodal; Implication that Nodal mediates the function of Arkadia in node induction.
Database: Psychology and Behavioral Sciences Collection
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 4345425
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Induction of the mammalian node requires Arkadia function in the extraembryonic lineages.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Episkopou%2C+Vasso%22">Episkopou, Vasso</searchLink><br /><searchLink fieldCode="AR" term="%22Arkell%2C+Ruth%22">Arkell, Ruth</searchLink><br /><searchLink fieldCode="AR" term="%22Timmons%2C+Paula+M%2E%22">Timmons, Paula M.</searchLink><br /><searchLink fieldCode="AR" term="%22Walsh%2C+James+J%2E%22">Walsh, James J.</searchLink><br /><searchLink fieldCode="AR" term="%22Andrew%2C+Rebecca+L%2E%22">Andrew, Rebecca L.</searchLink><br /><searchLink fieldCode="AR" term="%22Swan%2C+Daniel%22">Swan, Daniel</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Nature%22">Nature</searchLink>. 4/12/2001, Vol. 410 Issue 6830, p825. 6p. 27 Color Photographs, 1 Black and White Photograph, 2 Diagrams.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Embryonic+stem+cells%22">Embryonic stem cells</searchLink><br /><searchLink fieldCode="DE" term="%22Genetic+mutation%22">Genetic mutation</searchLink><br /><searchLink fieldCode="DE" term="%22Mutagenesis%22">Mutagenesis</searchLink><br /><searchLink fieldCode="DE" term="%22Transforming+growth+factors%22">Transforming growth factors</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Presents a study of arkadia, a recessive lethal mutation generated using gene-trap mutagenesis in embryonic stem cells. Analysis with chimaeras, which shows that Arkadia functions within extraembryonic tissues; Results which show that Arkadia interacts genetically with the transforming growth factor beta-like factor Nodal; Implication that Nodal mediates the function of Arkadia in node induction.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=4345425
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/35071095
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 6
        StartPage: 825
    Subjects:
      – SubjectFull: Embryonic stem cells
        Type: general
      – SubjectFull: Genetic mutation
        Type: general
      – SubjectFull: Mutagenesis
        Type: general
      – SubjectFull: Transforming growth factors
        Type: general
    Titles:
      – TitleFull: Induction of the mammalian node requires Arkadia function in the extraembryonic lineages.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Episkopou, Vasso
      – PersonEntity:
          Name:
            NameFull: Arkell, Ruth
      – PersonEntity:
          Name:
            NameFull: Timmons, Paula M.
      – PersonEntity:
          Name:
            NameFull: Walsh, James J.
      – PersonEntity:
          Name:
            NameFull: Andrew, Rebecca L.
      – PersonEntity:
          Name:
            NameFull: Swan, Daniel
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 12
              M: 04
              Text: 4/12/2001
              Type: published
              Y: 2001
          Identifiers:
            – Type: issn-print
              Value: 00280836
          Numbering:
            – Type: volume
              Value: 410
            – Type: issue
              Value: 6830
          Titles:
            – TitleFull: Nature
              Type: main
ResultId 1