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Perspectives on recent advances in the understanding and treatment of Parkinson’s disease.

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Title: Perspectives on recent advances in the understanding and treatment of Parkinson’s disease.
Authors: Schapira, A. H., Agid, Y., Barone, P., Jenner, P., Lemke, M. R., Poewe, W., Rascol, O., Reichmann, H., Tolosa, E.
Source: European Journal of Neurology. Oct2009, Vol. 16 Issue 10, p1090-1099. 10p. 3 Charts, 1 Graph.
Subjects: Parkinson's disease treatment, Mental depression, Dopamine agonists, Mitochondria, Dopa
Abstract: There have been numerous important recent advances in our understanding of the causes of Parkinson’s disease (PD), the treatments available and how these are best applied for the long-term management of patients. Novel genes causing familial PD have been discovered and mechanisms leading to cell dysfunction and death identified. The PD prodrome is now a subject of great interest and clinical markers are being defined that may in future, together with biochemical markers, support an early, pre-motor diagnosis of PD. This will become important as new therapies are developed to modify disease progression. In the interim, the optimization of existing therapies remains an important priority. The value of existing and novel continuous drug delivery systems in PD is seen as providing simplified regimens, maintenance of motor control, reduction in motor complications and improved patient adherence to drug use. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Perspectives on recent advances in the understanding and treatment of Parkinson’s disease.
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  Data: <searchLink fieldCode="AR" term="%22Schapira%2C+A%2E+H%2E%22">Schapira, A. H.</searchLink><br /><searchLink fieldCode="AR" term="%22Agid%2C+Y%2E%22">Agid, Y.</searchLink><br /><searchLink fieldCode="AR" term="%22Barone%2C+P%2E%22">Barone, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Jenner%2C+P%2E%22">Jenner, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Lemke%2C+M%2E+R%2E%22">Lemke, M. R.</searchLink><br /><searchLink fieldCode="AR" term="%22Poewe%2C+W%2E%22">Poewe, W.</searchLink><br /><searchLink fieldCode="AR" term="%22Rascol%2C+O%2E%22">Rascol, O.</searchLink><br /><searchLink fieldCode="AR" term="%22Reichmann%2C+H%2E%22">Reichmann, H.</searchLink><br /><searchLink fieldCode="AR" term="%22Tolosa%2C+E%2E%22">Tolosa, E.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neurology%22">European Journal of Neurology</searchLink>. Oct2009, Vol. 16 Issue 10, p1090-1099. 10p. 3 Charts, 1 Graph.
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  Data: <searchLink fieldCode="DE" term="%22Parkinson's+disease+treatment%22">Parkinson's disease treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Dopamine+agonists%22">Dopamine agonists</searchLink><br /><searchLink fieldCode="DE" term="%22Mitochondria%22">Mitochondria</searchLink><br /><searchLink fieldCode="DE" term="%22Dopa%22">Dopa</searchLink>
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  Data: There have been numerous important recent advances in our understanding of the causes of Parkinson’s disease (PD), the treatments available and how these are best applied for the long-term management of patients. Novel genes causing familial PD have been discovered and mechanisms leading to cell dysfunction and death identified. The PD prodrome is now a subject of great interest and clinical markers are being defined that may in future, together with biochemical markers, support an early, pre-motor diagnosis of PD. This will become important as new therapies are developed to modify disease progression. In the interim, the optimization of existing therapies remains an important priority. The value of existing and novel continuous drug delivery systems in PD is seen as providing simplified regimens, maintenance of motor control, reduction in motor complications and improved patient adherence to drug use. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=44183578
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