The Wisconsin Card Sorting Test and the assessment of frontal function in obsessive-compulsive patients: An event-related potential study.
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| Title: | The Wisconsin Card Sorting Test and the assessment of frontal function in obsessive-compulsive patients: An event-related potential study. |
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| Authors: | Sanz, Marta, Molina, Vicente, Calcedo, Alfredo, Martin-Loeches, Manuel, Rubia, Francisco J. |
| Source: | Cognitive Neuropsychiatry. May2001, Vol. 6 Issue 2, p109-129. 21p. |
| Subjects: | Obsessive-compulsive disorder, Wisconsin Card Sorting Test, Ability testing, Patients |
| Abstract: | The most consistent finding across the studies in obsessive-compulsive disorder (OCD) is the deficit in tasks involving shifting in cognitive set. The cognitive operations needed to perform the Wisconsin Card Sorting Test (WCST), searching for a new category and the consolidation of the correct classification category, are closely related to shifting cognitive set. This work aimed to study whether patients with OCD present difficulties in shifting cognitive set and to examine the topographical distribution of brain electrical changes and their temporal dynamics during the performance of the WCST. For this purpose, we selected 18 nondepressed OCD patients. The effects of clomipramine treatment on these variables were also assessed. Both behavioural and neuroelectric data supported the idea that OCD patients have an impaired capacity for shifting cognitive set. This deficit was interpreted as being due to problems in inhibitory control, as a consequence of a dysfunction in an inhibitory pathway in the prefrontal cortex. This would explain the poor performance of OCD patients in the WCST in terms of their inability to inhibit or suppress previous incorrect responses. Nevertheless, it is not clear whether shifting cognitive set is an enduring "trait" marker or a finding that fluctuates with changes in the clinical state. [ABSTRACT FROM AUTHOR] |
| Copyright of Cognitive Neuropsychiatry is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 4437919 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The Wisconsin Card Sorting Test and the assessment of frontal function in obsessive-compulsive patients: An event-related potential study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Sanz%2C+Marta%22">Sanz, Marta</searchLink><br /><searchLink fieldCode="AR" term="%22Molina%2C+Vicente%22">Molina, Vicente</searchLink><br /><searchLink fieldCode="AR" term="%22Calcedo%2C+Alfredo%22">Calcedo, Alfredo</searchLink><br /><searchLink fieldCode="AR" term="%22Martin-Loeches%2C+Manuel%22">Martin-Loeches, Manuel</searchLink><br /><searchLink fieldCode="AR" term="%22Rubia%2C+Francisco+J%2E%22">Rubia, Francisco J.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Cognitive+Neuropsychiatry%22">Cognitive Neuropsychiatry</searchLink>. May2001, Vol. 6 Issue 2, p109-129. 21p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Obsessive-compulsive+disorder%22">Obsessive-compulsive disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Wisconsin+Card+Sorting+Test%22">Wisconsin Card Sorting Test</searchLink><br /><searchLink fieldCode="DE" term="%22Ability+testing%22">Ability testing</searchLink><br /><searchLink fieldCode="DE" term="%22Patients%22">Patients</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: The most consistent finding across the studies in obsessive-compulsive disorder (OCD) is the deficit in tasks involving shifting in cognitive set. The cognitive operations needed to perform the Wisconsin Card Sorting Test (WCST), searching for a new category and the consolidation of the correct classification category, are closely related to shifting cognitive set. This work aimed to study whether patients with OCD present difficulties in shifting cognitive set and to examine the topographical distribution of brain electrical changes and their temporal dynamics during the performance of the WCST. For this purpose, we selected 18 nondepressed OCD patients. The effects of clomipramine treatment on these variables were also assessed. Both behavioural and neuroelectric data supported the idea that OCD patients have an impaired capacity for shifting cognitive set. This deficit was interpreted as being due to problems in inhibitory control, as a consequence of a dysfunction in an inhibitory pathway in the prefrontal cortex. This would explain the poor performance of OCD patients in the WCST in terms of their inability to inhibit or suppress previous incorrect responses. Nevertheless, it is not clear whether shifting cognitive set is an enduring "trait" marker or a finding that fluctuates with changes in the clinical state. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Cognitive Neuropsychiatry is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=4437919 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1080/13546800042000089 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 21 StartPage: 109 Subjects: – SubjectFull: Obsessive-compulsive disorder Type: general – SubjectFull: Wisconsin Card Sorting Test Type: general – SubjectFull: Ability testing Type: general – SubjectFull: Patients Type: general Titles: – TitleFull: The Wisconsin Card Sorting Test and the assessment of frontal function in obsessive-compulsive patients: An event-related potential study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sanz, Marta – PersonEntity: Name: NameFull: Molina, Vicente – PersonEntity: Name: NameFull: Calcedo, Alfredo – PersonEntity: Name: NameFull: Martin-Loeches, Manuel – PersonEntity: Name: NameFull: Rubia, Francisco J. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May2001 Type: published Y: 2001 Identifiers: – Type: issn-print Value: 13546805 Numbering: – Type: volume Value: 6 – Type: issue Value: 2 Titles: – TitleFull: Cognitive Neuropsychiatry Type: main |
| ResultId | 1 |
