Semantic Fluency Performance of Patients with Cortical and SubcorticalNeurodegenerative Diseases.
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| Title: | Semantic Fluency Performance of Patients with Cortical and SubcorticalNeurodegenerative Diseases. |
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| Authors: | Testa, Julie A., Tröster, Alexander I., Fields, Julie A., Gleason, Angela C., Salmon, David P., Beatty, William W. |
| Source: | Aging, Neuropsychology & Cognition. Sep98, Vol. 5 Issue 3, p203. 12p. |
| Subjects: | Neurodegeneration, Dementia patients |
| Abstract: | Previous studies using the Animals Fluency Test have shown that dementia patients with Alzheimer's disease (AD), Huntington's disease (HD), or Parkinson's disease (PD) produce fewer correct words and have smaller semantic cluster sizes than controls or PD patients without dementia (PDND). Although the number of correct words generated by the patients with AD was positively correlated with mental status, cluster size, surprisingly, was not. To increase word output and increase the reliability of estimates of cluster size, semantic fluency was reexamined using the Supermarket Fluency Task. Overall, patients with HD or PD with dementia (PDD) exhibited reduced cluster sizes compared to older controls or PDND patients, but cluster sizes were only marginally reduced for patients with AD. These effects were evident only for female participants, because the cluster sizes for elderly control men were substantially smaller than those of elderly women. For the female patients with AD, cluster size was correlated with mental status, but the relationship was nonlinear. Cluster size was normal for mildly demented patients with AD, but much reduced for moderately or severely demented participants. In contrast to a previous report, in the present study the proportion of category labels generated was increased for patients with HD with dementia but not for patients with AD. This finding questions one line of evidence that semantic memory stores undergo "bottom-up" degradation in AD. Together with previous results, these findings indicate that semantic cluster size reflects efficiency of access to semantic knowledge which is similarly compromised in subcortical and cortical diseases. [ABSTRACT FROM AUTHOR] |
| Copyright of Aging, Neuropsychology & Cognition is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 4556998 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Semantic Fluency Performance of Patients with Cortical and SubcorticalNeurodegenerative Diseases. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Testa%2C+Julie+A%2E%22">Testa, Julie A.</searchLink><br /><searchLink fieldCode="AR" term="%22Tröster%2C+Alexander+I%2E%22">Tröster, Alexander I.</searchLink><br /><searchLink fieldCode="AR" term="%22Fields%2C+Julie+A%2E%22">Fields, Julie A.</searchLink><br /><searchLink fieldCode="AR" term="%22Gleason%2C+Angela+C%2E%22">Gleason, Angela C.</searchLink><br /><searchLink fieldCode="AR" term="%22Salmon%2C+David+P%2E%22">Salmon, David P.</searchLink><br /><searchLink fieldCode="AR" term="%22Beatty%2C+William+W%2E%22">Beatty, William W.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Aging%2C+Neuropsychology+%26+Cognition%22">Aging, Neuropsychology & Cognition</searchLink>. Sep98, Vol. 5 Issue 3, p203. 12p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Neurodegeneration%22">Neurodegeneration</searchLink><br /><searchLink fieldCode="DE" term="%22Dementia+patients%22">Dementia patients</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Previous studies using the Animals Fluency Test have shown that dementia patients with Alzheimer's disease (AD), Huntington's disease (HD), or Parkinson's disease (PD) produce fewer correct words and have smaller semantic cluster sizes than controls or PD patients without dementia (PDND). Although the number of correct words generated by the patients with AD was positively correlated with mental status, cluster size, surprisingly, was not. To increase word output and increase the reliability of estimates of cluster size, semantic fluency was reexamined using the Supermarket Fluency Task. Overall, patients with HD or PD with dementia (PDD) exhibited reduced cluster sizes compared to older controls or PDND patients, but cluster sizes were only marginally reduced for patients with AD. These effects were evident only for female participants, because the cluster sizes for elderly control men were substantially smaller than those of elderly women. For the female patients with AD, cluster size was correlated with mental status, but the relationship was nonlinear. Cluster size was normal for mildly demented patients with AD, but much reduced for moderately or severely demented participants. In contrast to a previous report, in the present study the proportion of category labels generated was increased for patients with HD with dementia but not for patients with AD. This finding questions one line of evidence that semantic memory stores undergo "bottom-up" degradation in AD. Together with previous results, these findings indicate that semantic cluster size reflects efficiency of access to semantic knowledge which is similarly compromised in subcortical and cortical diseases. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Aging, Neuropsychology & Cognition is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1076/anec.5.3.203.612 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 12 StartPage: 203 Subjects: – SubjectFull: Neurodegeneration Type: general – SubjectFull: Dementia patients Type: general Titles: – TitleFull: Semantic Fluency Performance of Patients with Cortical and SubcorticalNeurodegenerative Diseases. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Testa, Julie A. – PersonEntity: Name: NameFull: Tröster, Alexander I. – PersonEntity: Name: NameFull: Fields, Julie A. – PersonEntity: Name: NameFull: Gleason, Angela C. – PersonEntity: Name: NameFull: Salmon, David P. – PersonEntity: Name: NameFull: Beatty, William W. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: Sep98 Type: published Y: 1998 Identifiers: – Type: issn-print Value: 13825585 Numbering: – Type: volume Value: 5 – Type: issue Value: 3 Titles: – TitleFull: Aging, Neuropsychology & Cognition Type: main |
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