Prevalence of and Risk Factors Associated with Abnormal Vertebral Artery Flow. The Tromsø Study.
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| Title: | Prevalence of and Risk Factors Associated with Abnormal Vertebral Artery Flow. The Tromsø Study. |
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| Authors: | Mathiesen*†, Ellisiv B., Joakimsen†, Oddmund, Bønaa, Kaare H. |
| Source: | Acta Neurologica Scandinavica. May2001, Vol. 103 Issue 5, p327. 7p. |
| Subjects: | Vertebral artery, Arterial stenosis, Blood flow measurement, Diseases |
| Abstract: | Purpose: To assess the prevalence and risk factors of abnormal vertebral artery flow in subjects with carotid stenosis and controls. Methods: Flow in the vertebral arteries was assessed by Duplex scanning and color-Doppler in 225 subjects with carotid artery stenosis and 221 controls matched by age and sex who participate in a population-based study on carotid stenosis. Flow was categorized as orthograde (=normal), retrograde or absent (not detectable), and association to risk factors and clinical events was analyzed. Results: Abnormal vertebral flow (absent/retrograde) was seen in 45 of the 446 subjects. It was more common in men than in women (14.0% vs. 4.4%, p=0.001), and in individuals with carotid stenosis compared to controls (13.3% vs. 6.7%, p=0.02). In univariate analysis, abnormal vertebral flow was associated with male gender, presence of carotid stenosis, diabetes, treated hypertension, HDL cholesterol (inverse), and body mass index, but not with age, smoking, total cholesterol, triglycerides, or fibrinogen. In multivariate analysis, abnormal vertebral flow was independently associated with male gender (p=0.002), hypertension (p=0.0002), and diabetes (p=0.02), and in controls only also with HDL cholesterol (inverse). Absence of vertebral flow was associated with previous stroke in the vertebro-basilar territory (p=0.0007). There was no significant association between retrograde flow and clinical events in the vertebro-basilar territory. Conclusion: The prevalence of abnormal flow in the vertebral artery was 13.3% in subjects with carotid stenosis and 6.7% in subjects without carotid artery stenosis, although the association observed in univariate analysis between body mass index and no detectable flow indicates that some misclassification occurred. Abnormal flow in the vertebral artery was associated with male gender, hypertension, diabetes and HDL cholesterol. Absence of vertebral flow was associated with previous stroke in the vertebro-basilar... [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 4592363 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Prevalence of and Risk Factors Associated with Abnormal Vertebral Artery Flow. The Tromsø Study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Mathiesen*†%2C+Ellisiv+B%2E%22">Mathiesen*†, Ellisiv B.</searchLink><br /><searchLink fieldCode="AR" term="%22Joakimsen†%2C+Oddmund%22">Joakimsen†, Oddmund</searchLink><br /><searchLink fieldCode="AR" term="%22Bønaa%2C+Kaare+H%2E%22">Bønaa, Kaare H.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Acta+Neurologica+Scandinavica%22">Acta Neurologica Scandinavica</searchLink>. May2001, Vol. 103 Issue 5, p327. 7p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Vertebral+artery%22">Vertebral artery</searchLink><br /><searchLink fieldCode="DE" term="%22Arterial+stenosis%22">Arterial stenosis</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+flow+measurement%22">Blood flow measurement</searchLink><br /><searchLink fieldCode="DE" term="%22Diseases%22">Diseases</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Purpose: To assess the prevalence and risk factors of abnormal vertebral artery flow in subjects with carotid stenosis and controls. Methods: Flow in the vertebral arteries was assessed by Duplex scanning and color-Doppler in 225 subjects with carotid artery stenosis and 221 controls matched by age and sex who participate in a population-based study on carotid stenosis. Flow was categorized as orthograde (=normal), retrograde or absent (not detectable), and association to risk factors and clinical events was analyzed. Results: Abnormal vertebral flow (absent/retrograde) was seen in 45 of the 446 subjects. It was more common in men than in women (14.0% vs. 4.4%, p=0.001), and in individuals with carotid stenosis compared to controls (13.3% vs. 6.7%, p=0.02). In univariate analysis, abnormal vertebral flow was associated with male gender, presence of carotid stenosis, diabetes, treated hypertension, HDL cholesterol (inverse), and body mass index, but not with age, smoking, total cholesterol, triglycerides, or fibrinogen. In multivariate analysis, abnormal vertebral flow was independently associated with male gender (p=0.002), hypertension (p=0.0002), and diabetes (p=0.02), and in controls only also with HDL cholesterol (inverse). Absence of vertebral flow was associated with previous stroke in the vertebro-basilar territory (p=0.0007). There was no significant association between retrograde flow and clinical events in the vertebro-basilar territory. Conclusion: The prevalence of abnormal flow in the vertebral artery was 13.3% in subjects with carotid stenosis and 6.7% in subjects without carotid artery stenosis, although the association observed in univariate analysis between body mass index and no detectable flow indicates that some misclassification occurred. Abnormal flow in the vertebral artery was associated with male gender, hypertension, diabetes and HDL cholesterol. Absence of vertebral flow was associated with previous stroke in the vertebro-basilar... [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 327 Subjects: – SubjectFull: Vertebral artery Type: general – SubjectFull: Arterial stenosis Type: general – SubjectFull: Blood flow measurement Type: general – SubjectFull: Diseases Type: general Titles: – TitleFull: Prevalence of and Risk Factors Associated with Abnormal Vertebral Artery Flow. The Tromsø Study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Mathiesen*†, Ellisiv B. – PersonEntity: Name: NameFull: Joakimsen†, Oddmund – PersonEntity: Name: NameFull: Bønaa, Kaare H. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May2001 Type: published Y: 2001 Identifiers: – Type: issn-print Value: 00016314 Numbering: – Type: volume Value: 103 – Type: issue Value: 5 Titles: – TitleFull: Acta Neurologica Scandinavica Type: main |
| ResultId | 1 |
