Comparison between eye movement latency and REM sleep parameters in major depression.
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| Title: | Comparison between eye movement latency and REM sleep parameters in major depression. |
|---|---|
| Authors: | Wichniak, A., Riemann, D., Kiemen, A., Voderholzer, U., Jernajczyk, W. |
| Source: | European Archives of Psychiatry & Clinical Neuroscience. 2000, Vol. 250 Issue 1, p48. 5p. |
| Subjects: | Depressed persons, Sleep, Eye movements, Bipolar disorder |
| Abstract: | Abstract Alterations of sleep can be observed polysomnographically in approximately 90 percent of depressed patients. Most of the registered sleep abnormalities in depression also occur in other psychiatric disorders. Only some types of REM sleep alterations - short REM latency, increase of REM density and shortening of mean latency of eye movements - were reported as more specific for affective disorders. In the present study polysomnograms of 21 medication free patients with major depressive disorder (assessed with a structured interview for DSM-III-R and Hamilton Scale) and 21 healthy controls were analysed. REM latency (LREM), REM density (RD), latencies of eye movements (LEM) and mean latency of eye movements (M-LEM) were calculated for both groups. Depressed patients (compared with healthy controls) showed increased RD (38.2% vs. 28.2%, p < 0.0001), shortened M-LEM (35.7 s vs. 48.3 s, p < 0.04) and shortening of LEM in the 1st (28.9 s vs. 48.9 s, p < 0.007) and 4th (27.0 s vs. 59.1 s, p < 0.043) REM sleep periods. LREM was not shortened significantly in depressives (78.5 min vs. 91.3 min, ns). In healthy subjects a negative correlation between M-LEM and RD was found (rho = - 0.47, p < 0.03). Since in the current study depressed patients differed from healthy controls, especially concerning phasic activity during REM sleep, presented data support the essential role of REM density for the assessment of sleep in depression. As a quick and easy manner to compute measurement, M-LEM is suggested as additional parameter for the assessment of phasic activity during REM sleep. [ABSTRACT FROM AUTHOR] |
| Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 4678547 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Comparison between eye movement latency and REM sleep parameters in major depression. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Wichniak%2C+A%2E%22">Wichniak, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Riemann%2C+D%2E%22">Riemann, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Kiemen%2C+A%2E%22">Kiemen, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Voderholzer%2C+U%2E%22">Voderholzer, U.</searchLink><br /><searchLink fieldCode="AR" term="%22Jernajczyk%2C+W%2E%22">Jernajczyk, W.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Archives+of+Psychiatry+%26+Clinical+Neuroscience%22">European Archives of Psychiatry & Clinical Neuroscience</searchLink>. 2000, Vol. 250 Issue 1, p48. 5p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Depressed+persons%22">Depressed persons</searchLink><br /><searchLink fieldCode="DE" term="%22Sleep%22">Sleep</searchLink><br /><searchLink fieldCode="DE" term="%22Eye+movements%22">Eye movements</searchLink><br /><searchLink fieldCode="DE" term="%22Bipolar+disorder%22">Bipolar disorder</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Abstract Alterations of sleep can be observed polysomnographically in approximately 90 percent of depressed patients. Most of the registered sleep abnormalities in depression also occur in other psychiatric disorders. Only some types of REM sleep alterations - short REM latency, increase of REM density and shortening of mean latency of eye movements - were reported as more specific for affective disorders. In the present study polysomnograms of 21 medication free patients with major depressive disorder (assessed with a structured interview for DSM-III-R and Hamilton Scale) and 21 healthy controls were analysed. REM latency (LREM), REM density (RD), latencies of eye movements (LEM) and mean latency of eye movements (M-LEM) were calculated for both groups. Depressed patients (compared with healthy controls) showed increased RD (38.2% vs. 28.2%, p < 0.0001), shortened M-LEM (35.7 s vs. 48.3 s, p < 0.04) and shortening of LEM in the 1st (28.9 s vs. 48.9 s, p < 0.007) and 4th (27.0 s vs. 59.1 s, p < 0.043) REM sleep periods. LREM was not shortened significantly in depressives (78.5 min vs. 91.3 min, ns). In healthy subjects a negative correlation between M-LEM and RD was found (rho = - 0.47, p < 0.03). Since in the current study depressed patients differed from healthy controls, especially concerning phasic activity during REM sleep, presented data support the essential role of REM density for the assessment of sleep in depression. As a quick and easy manner to compute measurement, M-LEM is suggested as additional parameter for the assessment of phasic activity during REM sleep. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s004060050009 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 48 Subjects: – SubjectFull: Depressed persons Type: general – SubjectFull: Sleep Type: general – SubjectFull: Eye movements Type: general – SubjectFull: Bipolar disorder Type: general Titles: – TitleFull: Comparison between eye movement latency and REM sleep parameters in major depression. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wichniak, A. – PersonEntity: Name: NameFull: Riemann, D. – PersonEntity: Name: NameFull: Kiemen, A. – PersonEntity: Name: NameFull: Voderholzer, U. – PersonEntity: Name: NameFull: Jernajczyk, W. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2000 Type: published Y: 2000 Identifiers: – Type: issn-print Value: 09401334 Numbering: – Type: volume Value: 250 – Type: issue Value: 1 Titles: – TitleFull: European Archives of Psychiatry & Clinical Neuroscience Type: main |
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