How to preserve the antidepressive effect of sleep deprivation: A comparison of sleep phase advance and sleep phase delay.
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| Title: | How to preserve the antidepressive effect of sleep deprivation: A comparison of sleep phase advance and sleep phase delay. |
|---|---|
| Authors: | Riemann, D., König, A., Hohagen, F., Kiemen, A., Voderholzer, U., Backhaus, J., Bunz, J., Wesiack, B., Hermle, L., Berger, M. |
| Source: | European Archives of Psychiatry & Clinical Neuroscience. 1999, Vol. 249 Issue 5, p231. 7p. |
| Subjects: | Mental depression, Sleep deprivation |
| Abstract: | Abstract Total sleep deprivation (TSD) leads to an immediate amelioration of depressed mood in approximately 70 % of patients with the melancholic subtype of depression. The clinical utility of this procedure is limited, as the improvement usually subsides after the next night of sleep. In the present study, 40 depressed inpatients, being free of psychoactive medication for at least 7 days and who had responded to a TSD were then distributed (according to a matched-pair design) to a sleep phase advance (SPA = time in bed scheduled from 1700-2400 hrs) or a sleep phase delay (SPD = time in bed from 0200-0700 hfs) with a succeeding shift back (for one hour in the SPA group per day) respectively shift forward (for 30 minutes in the SPD group per day), until the initial sleep phase (2300-0600 hfs) was reached after seven days again. Based on previous observations it was hypothesized that a phase advance of the sleep period should prevent responders to TSD from relapsing. Whereas 75% of the TSD responders were stabilized by the phase advanced condition and did not relapse over a period of seven days, only 40% of the patients in the phase delayed condition did not relapse. Polysomnography during the course of the study gave no evidence that the unusual sleep schedules caused prolonged sleep deprivation. Abnormalities of REM sleep persisted both in the clinical responders and non-responders after the sleep wake manipulation. It is concluded that the clinical effectiveness of TSD can be significantly improved by combining TSD with a following phase advance of the sleep period. [ABSTRACT FROM AUTHOR] |
| Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 4678628 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: How to preserve the antidepressive effect of sleep deprivation: A comparison of sleep phase advance and sleep phase delay. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Riemann%2C+D%2E%22">Riemann, D.</searchLink><br /><searchLink fieldCode="AR" term="%22König%2C+A%2E%22">König, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Hohagen%2C+F%2E%22">Hohagen, F.</searchLink><br /><searchLink fieldCode="AR" term="%22Kiemen%2C+A%2E%22">Kiemen, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Voderholzer%2C+U%2E%22">Voderholzer, U.</searchLink><br /><searchLink fieldCode="AR" term="%22Backhaus%2C+J%2E%22">Backhaus, J.</searchLink><br /><searchLink fieldCode="AR" term="%22Bunz%2C+J%2E%22">Bunz, J.</searchLink><br /><searchLink fieldCode="AR" term="%22Wesiack%2C+B%2E%22">Wesiack, B.</searchLink><br /><searchLink fieldCode="AR" term="%22Hermle%2C+L%2E%22">Hermle, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Berger%2C+M%2E%22">Berger, M.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Archives+of+Psychiatry+%26+Clinical+Neuroscience%22">European Archives of Psychiatry & Clinical Neuroscience</searchLink>. 1999, Vol. 249 Issue 5, p231. 7p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Sleep+deprivation%22">Sleep deprivation</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Abstract Total sleep deprivation (TSD) leads to an immediate amelioration of depressed mood in approximately 70 % of patients with the melancholic subtype of depression. The clinical utility of this procedure is limited, as the improvement usually subsides after the next night of sleep. In the present study, 40 depressed inpatients, being free of psychoactive medication for at least 7 days and who had responded to a TSD were then distributed (according to a matched-pair design) to a sleep phase advance (SPA = time in bed scheduled from 1700-2400 hrs) or a sleep phase delay (SPD = time in bed from 0200-0700 hfs) with a succeeding shift back (for one hour in the SPA group per day) respectively shift forward (for 30 minutes in the SPD group per day), until the initial sleep phase (2300-0600 hfs) was reached after seven days again. Based on previous observations it was hypothesized that a phase advance of the sleep period should prevent responders to TSD from relapsing. Whereas 75% of the TSD responders were stabilized by the phase advanced condition and did not relapse over a period of seven days, only 40% of the patients in the phase delayed condition did not relapse. Polysomnography during the course of the study gave no evidence that the unusual sleep schedules caused prolonged sleep deprivation. Abnormalities of REM sleep persisted both in the clinical responders and non-responders after the sleep wake manipulation. It is concluded that the clinical effectiveness of TSD can be significantly improved by combining TSD with a following phase advance of the sleep period. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s004060050092 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 231 Subjects: – SubjectFull: Mental depression Type: general – SubjectFull: Sleep deprivation Type: general Titles: – TitleFull: How to preserve the antidepressive effect of sleep deprivation: A comparison of sleep phase advance and sleep phase delay. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Riemann, D. – PersonEntity: Name: NameFull: König, A. – PersonEntity: Name: NameFull: Hohagen, F. – PersonEntity: Name: NameFull: Kiemen, A. – PersonEntity: Name: NameFull: Voderholzer, U. – PersonEntity: Name: NameFull: Backhaus, J. – PersonEntity: Name: NameFull: Bunz, J. – PersonEntity: Name: NameFull: Wesiack, B. – PersonEntity: Name: NameFull: Hermle, L. – PersonEntity: Name: NameFull: Berger, M. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 1999 Type: published Y: 1999 Identifiers: – Type: issn-print Value: 09401334 Numbering: – Type: volume Value: 249 – Type: issue Value: 5 Titles: – TitleFull: European Archives of Psychiatry & Clinical Neuroscience Type: main |
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