Bibliographic Details
| Title: |
Ambulatory Blood Pressure Patterns in Children and Adolescents: Influence of Renin-Sodium Profiles. |
| Authors: |
Harshfield, Gregory A., Pulliam, Derrick A., Alpert, Bruce S., Stapleton, F. Bruder, Willey, Elaine S., Somes, Grant W. |
| Source: |
Pediatrics. Jan91, Vol. 87 Issue 1, p94. 7p. |
| Subjects: |
Ambulatory blood pressure monitoring, Renin, Physiological effects of sodium, Chemical inhibitors |
| Abstract: |
Abstract. A renin-sodium nomogram for normotensive children and adolescents was developed at our institution. The ambulatory blood pressure patterns of subjects classified by the nomogram were then compared. A biracial sample of 159 children and adolescents were classified as having a low, intermediate, or high renin-sodium profile based on the relationship between their plasma renin activity and 24-hour urinary sodium excretion. Casual (106/58 vs 107/61 vs 106/62 mm Hg) and awake (116/69 vs 117/69 vs 116/70 mm Hg) blood pressure values were comparable among subjects with low, intermediate, and high renin-sodium profiles. Subjects with high renin-sodium profiles, however, had a smaller decline in systolic blood pressure with sleep than did subjects with low renin-sodium profiles (7 vs 11 mm Hg; P < .04), and higher diastolic blood pressure readings during sleep than subjects with intermediate renin-sodium profiles (65 vs 62 mm Hg; P < .05). Subjects with high renin-sodium profiles also had greater variance of diastolic blood pressure readings during sleep than either subjects with low renin-sodium profiles (P < .01) or those with intermediate renin-sodium profiles (P < .02). The blunted nocturnal decline and increased nocturnal variance of blood pressure among subjects with high renin-sodium profiles may be a marker or mechanism for the future development of essential hypertension. Pediatrics 1991;87:94-100; ambulatory blood pressure, renin-sodium profile, adolescent blood pressure, hypertension. [ABSTRACT FROM AUTHOR] |
|
Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Psychology and Behavioral Sciences Collection |
