Semi-quantitative evaluation of endolymphatic hydrops by bilateral intratympanic gadolinium-based contrast agent (GBCA) administration with MRI for Meniere's disease.
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| Title: | Semi-quantitative evaluation of endolymphatic hydrops by bilateral intratympanic gadolinium-based contrast agent (GBCA) administration with MRI for Meniere's disease. |
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| Authors: | Fukuoka, Hisakuni (AUTHOR), Tsukada, Keita (AUTHOR), Miyagawa, Maiko (AUTHOR), Oguchi, Tomohiro (AUTHOR), Takumi, Yutaka (AUTHOR), Sugiura, Makoto (AUTHOR), Ueda, Hitoshi (AUTHOR), Kadoya, Masumi (AUTHOR), Usami, Shin-Ichi (AUTHOR) |
| Source: | Acta Oto-Laryngologica. Jan2010, Vol. 130 Issue 1, p10-16. 7p. 2 Black and White Photographs, 2 Charts, 2 Graphs. |
| Subjects: | Ménière's disease, Inner ear diseases, Gadolinium, Contrast-enhanced magnetic resonance imaging, Deafness prevention, Diagnosis, Therapeutics |
| Abstract: | Conclusion: Bilateral intratympanic administration of a gadolinium-based contrast agent (GBCA) in MRI was successfully performed and proved to be beneficial in the semi-quantitative evaluation of endolymphatic hydrops. Such image-based diagnosis will lead to re-revaluation and reclassification of the diagnostic criteria for Meniere's disease (MD). Objective: To visualize endolymphatic hydrops semi-quantitatively in patients with MD, by using bilateral intratympanic GBCA administration with MRI. Patients and methods: A total of 13 patients were evaluated, including 12 with MD and one with acute low-tone sensorineural hearing loss. Diluted gadodiamide (a kind of GBCA) was administered to the bilateral tympanic cavity by injection through the tympanic membrane. After 24 h, the endolymphatic hydrops was evaluated with a 3.0 T MR scanner. The areas enhanced by gadodiamide were measured semi-quantitatively. Results: Three-dimensional, fluid-attenuated inversion recovery (3D-FLAIR) MRI showed that the gadodiamide successfully penetrated the round window membrane, entering the perilymphatic space and delineating the gadodiamide-enhanced perilymphatic and gadodiamide-negative endolymphatic spaces of the inner ear. All the patients with MD showed a reduced gadodiamide-enhanced area representing the perilymphatic space, and the quantitative ratio was 0.15 to 0.85. Furthermore, endolymphatic hydrops was also demonstrated in the patient with atypical MD who had fluctuating low frequency sensorineural hearing loss without vertigo. [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 47585928 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Semi-quantitative evaluation of endolymphatic hydrops by bilateral intratympanic gadolinium-based contrast agent (GBCA) administration with MRI for Meniere's disease. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Fukuoka%2C+Hisakuni%22">Fukuoka, Hisakuni</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tsukada%2C+Keita%22">Tsukada, Keita</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Miyagawa%2C+Maiko%22">Miyagawa, Maiko</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Oguchi%2C+Tomohiro%22">Oguchi, Tomohiro</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Takumi%2C+Yutaka%22">Takumi, Yutaka</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sugiura%2C+Makoto%22">Sugiura, Makoto</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ueda%2C+Hitoshi%22">Ueda, Hitoshi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kadoya%2C+Masumi%22">Kadoya, Masumi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Usami%2C+Shin-Ichi%22">Usami, Shin-Ichi</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Acta+Oto-Laryngologica%22">Acta Oto-Laryngologica</searchLink>. Jan2010, Vol. 130 Issue 1, p10-16. 7p. 2 Black and White Photographs, 2 Charts, 2 Graphs. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Ménière's+disease%22">Ménière's disease</searchLink><br /><searchLink fieldCode="DE" term="%22Inner+ear+diseases%22">Inner ear diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Gadolinium%22">Gadolinium</searchLink><br /><searchLink fieldCode="DE" term="%22Contrast-enhanced+magnetic+resonance+imaging%22">Contrast-enhanced magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Deafness+prevention%22">Deafness prevention</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnosis%22">Diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Conclusion: Bilateral intratympanic administration of a gadolinium-based contrast agent (GBCA) in MRI was successfully performed and proved to be beneficial in the semi-quantitative evaluation of endolymphatic hydrops. Such image-based diagnosis will lead to re-revaluation and reclassification of the diagnostic criteria for Meniere's disease (MD). Objective: To visualize endolymphatic hydrops semi-quantitatively in patients with MD, by using bilateral intratympanic GBCA administration with MRI. Patients and methods: A total of 13 patients were evaluated, including 12 with MD and one with acute low-tone sensorineural hearing loss. Diluted gadodiamide (a kind of GBCA) was administered to the bilateral tympanic cavity by injection through the tympanic membrane. After 24 h, the endolymphatic hydrops was evaluated with a 3.0 T MR scanner. The areas enhanced by gadodiamide were measured semi-quantitatively. Results: Three-dimensional, fluid-attenuated inversion recovery (3D-FLAIR) MRI showed that the gadodiamide successfully penetrated the round window membrane, entering the perilymphatic space and delineating the gadodiamide-enhanced perilymphatic and gadodiamide-negative endolymphatic spaces of the inner ear. All the patients with MD showed a reduced gadodiamide-enhanced area representing the perilymphatic space, and the quantitative ratio was 0.15 to 0.85. Furthermore, endolymphatic hydrops was also demonstrated in the patient with atypical MD who had fluctuating low frequency sensorineural hearing loss without vertigo. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3109/00016480902858881 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 10 Subjects: – SubjectFull: Ménière's disease Type: general – SubjectFull: Inner ear diseases Type: general – SubjectFull: Gadolinium Type: general – SubjectFull: Contrast-enhanced magnetic resonance imaging Type: general – SubjectFull: Deafness prevention Type: general – SubjectFull: Diagnosis Type: general – SubjectFull: Therapeutics Type: general Titles: – TitleFull: Semi-quantitative evaluation of endolymphatic hydrops by bilateral intratympanic gadolinium-based contrast agent (GBCA) administration with MRI for Meniere's disease. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fukuoka, Hisakuni – PersonEntity: Name: NameFull: Tsukada, Keita – PersonEntity: Name: NameFull: Miyagawa, Maiko – PersonEntity: Name: NameFull: Oguchi, Tomohiro – PersonEntity: Name: NameFull: Takumi, Yutaka – PersonEntity: Name: NameFull: Sugiura, Makoto – PersonEntity: Name: NameFull: Ueda, Hitoshi – PersonEntity: Name: NameFull: Kadoya, Masumi – PersonEntity: Name: NameFull: Usami, Shin-Ichi IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan2010 Type: published Y: 2010 Identifiers: – Type: issn-print Value: 00016489 Numbering: – Type: volume Value: 130 – Type: issue Value: 1 Titles: – TitleFull: Acta Oto-Laryngologica Type: main |
| ResultId | 1 |
