Gram-Negative Cerebrospinal Fluid Shunt-Association Infections.
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| Title: | Gram-Negative Cerebrospinal Fluid Shunt-Association Infections. |
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| Authors: | Sells, Clifford J., Shurtleff, David B., Loeser, John D. |
| Source: | Pediatrics. Apr77, Vol. 59 Issue 4, p614. 5p. |
| Subjects: | Nervous system, Cerebrospinal fluid shunts, Hydrocephalus in children, Infection |
| Abstract: | Abstract. Twenty hydrocephalic children with cerebrospinal fluid (CSF) shunts over an 11-year period were seen with Grain-negative central nervous system (CNS) infections. Seventeen infections were with single organisms and three were mixed. Sixteen of 20 (80%) of the infections occurred within five months of shunt surgery. Complete shunt removal or replacement m a new site plus systemic and intraventricular antibiotics resulted in a 100% (9/9) cure rate. Systemic and intraventricular antibiotics alone or in combination with incomplete shunt removal generally were unsuccessful. Significant morbidity and mortality were associated with these infections. Of the 18 patients with follow-up data, seven (39%) died with the infection, four (22%) sustained definite CNS damage, three (17%) were retarded after infection but their preinfection status was unknown, and only four (22%) patients escaped without definite sequelae. Early recognition and appropriate therapy, hopefully, will improve the current bleak prognosis. [ABSTRACT FROM AUTHOR] |
| Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 4763924 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Gram-Negative Cerebrospinal Fluid Shunt-Association Infections. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Sells%2C+Clifford+J%2E%22">Sells, Clifford J.</searchLink><br /><searchLink fieldCode="AR" term="%22Shurtleff%2C+David+B%2E%22">Shurtleff, David B.</searchLink><br /><searchLink fieldCode="AR" term="%22Loeser%2C+John+D%2E%22">Loeser, John D.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Pediatrics%22">Pediatrics</searchLink>. Apr77, Vol. 59 Issue 4, p614. 5p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Nervous+system%22">Nervous system</searchLink><br /><searchLink fieldCode="DE" term="%22Cerebrospinal+fluid+shunts%22">Cerebrospinal fluid shunts</searchLink><br /><searchLink fieldCode="DE" term="%22Hydrocephalus+in+children%22">Hydrocephalus in children</searchLink><br /><searchLink fieldCode="DE" term="%22Infection%22">Infection</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Abstract. Twenty hydrocephalic children with cerebrospinal fluid (CSF) shunts over an 11-year period were seen with Grain-negative central nervous system (CNS) infections. Seventeen infections were with single organisms and three were mixed. Sixteen of 20 (80%) of the infections occurred within five months of shunt surgery. Complete shunt removal or replacement m a new site plus systemic and intraventricular antibiotics resulted in a 100% (9/9) cure rate. Systemic and intraventricular antibiotics alone or in combination with incomplete shunt removal generally were unsuccessful. Significant morbidity and mortality were associated with these infections. Of the 18 patients with follow-up data, seven (39%) died with the infection, four (22%) sustained definite CNS damage, three (17%) were retarded after infection but their preinfection status was unknown, and only four (22%) patients escaped without definite sequelae. Early recognition and appropriate therapy, hopefully, will improve the current bleak prognosis. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1542/peds.59.4.614 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 614 Subjects: – SubjectFull: Nervous system Type: general – SubjectFull: Cerebrospinal fluid shunts Type: general – SubjectFull: Hydrocephalus in children Type: general – SubjectFull: Infection Type: general Titles: – TitleFull: Gram-Negative Cerebrospinal Fluid Shunt-Association Infections. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sells, Clifford J. – PersonEntity: Name: NameFull: Shurtleff, David B. – PersonEntity: Name: NameFull: Loeser, John D. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: Apr77 Type: published Y: 1977 Identifiers: – Type: issn-print Value: 00314005 Numbering: – Type: volume Value: 59 – Type: issue Value: 4 Titles: – TitleFull: Pediatrics Type: main |
| ResultId | 1 |
