Endolymphatic hydrops and therapeutic effects are visualized in ‘atypical’ Meniere's disease.
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| Title: | Endolymphatic hydrops and therapeutic effects are visualized in ‘atypical’ Meniere's disease. |
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| Authors: | Miyagawa, Maiko (AUTHOR), Fukuoka, Hisakuni (AUTHOR), Tsukada, Keita (AUTHOR), Oguchi, Tomohiro (AUTHOR), Takumi, Yutaka (AUTHOR), Sugiura, Makoto (AUTHOR), Ueda, Hitoshi (AUTHOR), Kadoya, Masumi (AUTHOR), Usami, Shin-Ichi (AUTHOR) |
| Source: | Acta Oto-Laryngologica. Nov2009, Vol. 129 Issue 11, p1326-1329. 4p. 3 Graphs. |
| Subjects: | Ménière's disease, Isosorbide dinitrate (Drug), Diagnostic imaging, Ear, Magnetic resonance imaging, Diagnosis |
| Abstract: | A 53-year-old male with fluctuating low frequency sensorineural hearing loss and tinnitus, but without vertigo, was evaluated by MRI obtained by intratympanic injection of a gadolinium-based contrast agent (GBCA) before and after the administration of isosorbide. The endolymphatic hydrops was semi-quantitatively evaluated by a 3.0-T MR scanner. For quantification, the affected side/contralateral side ratios were calculated. A gadodiamide (a kind of GBCA)-enhanced space surrounding the endolymph in the affected side with a 0.50 ratio (which may have represented endolymphatic hydrops) improved after isosorbide therapy to a 0.98 ratio. Thus, endolymphatic hydrops was demonstrated in a patient with ‘atypical’ Meniere's disease (MD), suggesting that at least some atypical MD may share similar etiology with, and therefore be a continuum of, MD. Also, therapeutic effects could be visualized by using MRI. Therefore, MRI-based diagnosis of MD-related disease will be a powerful tool not only because of its precision but also its usefulness for therapeutic evaluation. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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